Patents by Inventor James E. Stephan
James E. Stephan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9969971Abstract: The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.Type: GrantFiled: March 4, 2013Date of Patent: May 15, 2018Assignee: CAP Biotechnology, Inc.Inventors: L. Brian Starling, James E. Stephan
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Publication number: 20130243737Abstract: The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.Type: ApplicationFiled: March 4, 2013Publication date: September 19, 2013Applicant: CAP BIOTECHNOLOGY INCInventors: L. Brian Starling, James E. Stephan
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Patent number: 8389017Abstract: The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.Type: GrantFiled: July 7, 2000Date of Patent: March 5, 2013Assignee: Cap Biotechnology, Inc.Inventors: L. Brian Starling, James E. Stephan
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Patent number: 6358532Abstract: The present invention provides calcium phosphate-based (CaP) microcarriers and their use, for example, in cell culturing systems, chromatography, and implantable biomedical materials.Type: GrantFiled: February 15, 2001Date of Patent: March 19, 2002Assignee: CaP Biotechnology, Inc.Inventors: L. Brian Starling, James E. Stephan
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Patent number: 6346317Abstract: The present invention relates to electronic components and in particular relates to ceramic-based electronic components wherein a portion of the component comprises a metal-infiltrated ceramic. In a preferred embodiment, the metal-infiltrated ceramic comprises copper metal.Type: GrantFiled: March 19, 1997Date of Patent: February 12, 2002Assignee: CoorsTek, Inc.Inventors: Marcus A. Ritland, Dennis W. Readey, Jack D. Sibold, James E. Stephan
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Publication number: 20010021389Abstract: The present invention provides calcium phosphate-based (CaP) microcarriers and their use, for example, in cell culturing systems, chromatography, and implantable biomedical materials.Type: ApplicationFiled: February 15, 2001Publication date: September 13, 2001Applicant: CaP BIOTECHNOLOGY, INC.Inventors: L. Brian Starling, James E. Stephan
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Patent number: 6210715Abstract: The present invention provides calcium phosphate-based (CAP) microcarriers and microspheres and their use in cell culturing systems, chromatography and implantable biomedical materials.Type: GrantFiled: February 2, 2000Date of Patent: April 3, 2001Assignee: CaP Biotechnology, Inc.Inventors: L. Brian Starling, James E. Stephan
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Patent number: 6143421Abstract: The present invention relates to electronic components and in particular relates to ceramic-based electronic components wherein a portion of the component comprises a metal-infiltrated ceramic. In a preferred embodiment, the metal-infiltrated ceramic comprises copper metal.Type: GrantFiled: October 13, 1997Date of Patent: November 7, 2000Assignee: Coorstek, Inc.Inventors: Marcus A. Ritland, Dennis W. Readey, James E. Stephan, Dean A. Rulis, Jack D. Sibold
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Patent number: 5676907Abstract: A process for fabricating ceramic-metal composites having continuous ceramic and metallic phases. The process includes the steps of contacting a porous ceramic matrix material having the general shape of an article of manufacture with molten metal whereby capillary action pulls the metal into the open porosity of the ceramic matrix to substantially fill the open void space. The present invention also provides a ceramic-metal composite having continuous metal and ceramic phases.Type: GrantFiled: March 31, 1994Date of Patent: October 14, 1997Assignee: Coors Ceramics CompanyInventors: Marcus A. Ritland, Dennis W. Readey, James E. Stephan, Dean A. Rulis, Jack D. Sibold
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Patent number: 5614043Abstract: The present invention relates to electronic components and in particular relates to ceramic-based electronic components wherein a portion of the component comprises a metal-infiltrated ceramic. In a preferred embodiment, the metal-infiltrated ceramic comprises copper metal.Type: GrantFiled: March 31, 1994Date of Patent: March 25, 1997Assignee: Coors Ceramics CompanyInventors: Marcus A. Ritland, Dennis W. Readey, Jack D. Sibold, James E. Stephan
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Patent number: 4839215Abstract: Biocompatible particles and an article incorporating a plurality of such particles is disclosed. The particles can have means for interconnecting such as an aperture for stringing the particles on a filament or interlocking external shape. A plurality of particles, with or without means for interconnecting, can be fashioned into an article by interconnecting the particles with a flexible material. When the particles have a means for interconnecting, the plurality of particles can also be interconnected by a rigid material. The particles or plurality of interconnected particles are useful for medical, dental or veterinary or biotechnical applications, such as bone, tooth or skin implants, including alveolar ridge augmentation, or as a growth substrate material. Any biocompatible material can be used, including ceramics such a hydroxylapatite.Type: GrantFiled: June 9, 1986Date of Patent: June 13, 1989Assignee: Ceramed CorporationInventors: L. Brian Starling, James E. Stephan, William G. Hubbard
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Patent number: 4374076Abstract: A method for making cast precision epoxy resin bodies and an epoxy resin formulation for use therein, the epoxy resin formulation having Component A consisting essentially of from 40 to 70% by weight epoxy novolac polymer, from 30 to 50% by weight vinyl -3-cyclohexene diepoxide and from 0 to 20% by weight 3,4 epoxy cyclohexylmethyl -3,4-epoxy cyclohexane carboxylate and Component B consisting essentially of partially hydrolyzed aryl tetracarboxylic acid dianhydride, preferably partially hydrolyzed pyromellitic acid dianhydride. In the preferred embodiments a tertiary amine catalyst is also included. These components are mixed, just before use, in a ratio of from 20 to 50 parts by weight Component B to each 100 parts by weight Component A.Type: GrantFiled: October 9, 1981Date of Patent: February 15, 1983Assignee: Coors Porcelain CompanyInventors: James E. Stephan, Paul A. Boduch, John A. Elverum
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Patent number: 4265669Abstract: The invention provides a hard, strong ceramic body and a ceramic raw batch and method for manufacture whereby the body, after being formed of the raw batch in the shape and size desired, can then be fired to monolithic structure without any shrinkage or distortion during the firing operation. The raw batch contains aluminum oxide, magnesium oxide, glass frit and a silicone resin, these constituents being present in a ratio such that after the firing operation the resulting monolithic body contains from about 70% to 95% by weight crystalline material and the remainder interstitial glass, the crystalline material consisting predominantly of magnesium aluminate spinel and alumina. The ceramic and method have particular utility for making dental crowns and other dental appliances where a precise fit along with high strength and wear resistance are desirable.Type: GrantFiled: December 14, 1979Date of Patent: May 5, 1981Assignees: Coors Porcelain Company, Ralph B. Sozio, Edwin J. RileyInventors: Lynn B. Starling, James E. Stephan, Robert D. Stroud