Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.

Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Abstract: The invention provides isolated nucleic acids molecules, designated VELP2 nucleic acid molecules, which are expressed in endothelial cells and which encode proteins which contain LIM domains. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing VELP2 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a VELP2 gene has been introduced or disrupted. The invention still further provides isolated VELP2 proteins, fusion proteins, antigenic peptides and anti-VELP2 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: A DNA sequence encoding a human adenylyl cyclase is described. The amino acid sequence of the adenylyl cyclase is also described.

Abstract: A DNA sequence encoding a human adenylyl cyclase is described. The amino acid sequence of the adenylyl cyclase is also described.

Abstract: A DNA sequence encoding a human adenylyl cyclase is described. The amino acid sequence of the adenylyl cyclase is also described.

Abstract: A DNA sequence encoding a human adenylyl cyclase is described.

Abstract: A DNA sequence encoding a human type V adenylyl cyclase is described. The amino acid sequence of the adenylyl cyclase is also described. This adenylyl cyclase is expressed at increased levels in heart and brain tissue, relative to other tissues.

Abstract: A DNA sequence encoding a human adenylyl cyclase is described. The amino acid sequence of the adenylyl cyclase is also described.

Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.

Abstract: This invention provides antibodies that bind to epitopes of human platelet-derived growth factor receptor (hPDGF-R) fragments, wherein the fragments comprise one or more platelet-derived growth factor (PDGF) ligand binding regions from extracellular domains D1, D2, and D3. Also provided are antibodies specific for domain D3, such as monoclonal antibodies directed to the intra-cysteine portion of domain D3.

Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.

Abstract: The inspection line pan has an opening (11), in its deck plate (10) and a three-piece door (12) located in the opening. The door is formed of three rectangular panels (15, 16, 17) of similar length and width which are disposed transversely of each other. The outer panels (15, 17) are pivotally connected to the center panel (16) and the center panel has transverse grooves (18) which are supported on tongues on central portions of the opening (10) for transverse movement. In use, one or other outer panel can be pivotally raised for inspection below the line pan. If access to the area below the line pan is required, the center panel can be slid transversely into the space created by the raised outer panel and after the center panel is free of the tongues, it can be lifted clear of the opening. If the outer panels are attached to the center panel, they are lifted clear of the opening with the center panel; otherwise they are removed separately.

Abstract: A line pan for an AFC conveyor including a pair of sigma-section sides parallel and transversely spaced, a deck plate between the sides, and a base plate to which the sides are attached. The upper part of each sigma-section side and the deck plate are removably attached to the lower parts of the sigma-section sides and the base plate, and the deck plate has a transversely slidable section which can slide out of the deck plate for inspection of the conveyor components below the deck plate.

Abstract: The drive gearbox comprises an in-line primary box, a right-angled primary box and a nose module which can be coupled to one or both primary boxes. Each primary box has an open-ended interface which exposes gearing and the nose module has two open interfaces which expose gearing when the primary boxes are coupled to the nose modules, the gearings mesh with the gearing.If only one primary box is coupled to the nose module, a cover (not shown) is placed over the open interface.A gearbox formed of nose module and one or both primary boxes are advantageous in several ways, such as adaptability, power capacity, shape and size and design.