Patents by Inventor James Eaglesham

James Eaglesham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CGAS/DNCV-like nucleotidyltransferases and uses thereof
    Patent number: 12545900
    Abstract: The present invention is based, in part, on the discovery and characterization of the CD-NTase family of proteins, as well as compositions comprising CD-NTases, methods of producing nucleotide-based second messengers using such polypeptides, and methods of screening for modulators of the structure, expression, and/or activity of such polypeptides.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: February 10, 2026
    Assignees: Dana-Farber Cancer Institute, Inc., President and Fellows of Harvard College
    Inventors: Aaron Whiteley, Philip J. Kranzusch, John Mekalanos, James Eaglesham
  • CGAS/DNCV-LIKE NUCLEOTIDYLTRANSFERASES AND USES THEREOF
    Publication number: 20220127586
    Abstract: The present invention is based, in part, on the discovery and characterization of the CD-NTase family of proteins, as well as compositions comprising CD-NTases, methods of producing nucleotide-based second messengers using such polypeptides, and methods of screening for modulators of the structure, expression, and/or activity of such polypeptides.
    Type: Application
    Filed: September 4, 2019
    Publication date: April 28, 2022
    Inventors: Aaron Whiteley, Philip J. Kranzusch, John Mekalanos, James Eaglesham