Patents by Inventor James Edinger
James Edinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230142803Abstract: Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.Type: ApplicationFiled: November 16, 2022Publication date: May 11, 2023Applicant: Celularity Inc.Inventors: Xiaokui ZHANG, Ivana DJURETIC, Lin KANG, Vanessa VOSKINARIAN-BERSE, Bhavani STOUT, Robert J. HARIRI, Wolfgang HOFGARTNER, James EDINGER, Eric LAW, Vladimer JANKOVIC
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Publication number: 20220251104Abstract: Disclosed herein are new aromatic compounds, compositions that include one or more aromatic compounds, and methods of synthesizing the same. Also disclosed herein are methods of increasing and/or expanding cells, including stem cells, hematopoietic stem cells, progenitor cells, and placenta or cord blood-derived cells, with one or more compounds or compositions described herein. Also disclosed herein are methods of increasing and/or expanding differentiated hematopoietic cells with one or more compounds or compositions described herein.Type: ApplicationFiled: November 29, 2019Publication date: August 11, 2022Applicant: Celularity Inc.Inventors: Robert J. HARIRI, Xiaokui ZHANG, James EDINGER
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Publication number: 20210095258Abstract: The present invention provides an induced pluripotent stem (iPS) cell, or population of iPS cells, wherein the cell or cells giving rise to the iPS cell(s) are obtained from human postpartum tissue or cells, wherein the iPS cell(s) have increased levels of one or more factors selected from Group I: an Oct family member, a Sox family member, a Klf family member, a Myc family member, Nanog, Lin28, and combinations thereof. The present invention also provides differentiated cells derived from the cells of the invention and compositions, including pharmaceutical compositions comprising the cells of the invention. The invention further provides uses of the cells of the invention, e.g., in the treatment of a subject suffering from a disease of disorder. The invention additionally provides methods of generating iPS cell(s) from postpartum tissue, such as the cells of the invention.Type: ApplicationFiled: February 22, 2019Publication date: April 1, 2021Applicant: Celularity Inc.Inventors: James EDINGER, Robert J. HARIRI, Sourav SINHA, Xiaokui ZHANG
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Patent number: 10383897Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: GrantFiled: June 10, 2015Date of Patent: August 20, 2019Assignee: Celularity, Inc.Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert Hariri
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Publication number: 20180346877Abstract: Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.Type: ApplicationFiled: October 14, 2016Publication date: December 6, 2018Applicant: CELULARITY, INC.Inventors: Xiaokui ZHANG, Ivana DJURETIC, Lin KANG, Vanessa VOSKINARIAN-BERSE, Bhavani STOUT, Robert J. HARIRI, Wolfgang HOFGARTNER, James EDINGER, Eric LAW, Vladimir JANKOVIC
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Publication number: 20180071343Abstract: Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.Type: ApplicationFiled: November 16, 2017Publication date: March 15, 2018Applicant: Celularity, Inc.Inventors: Stewart Abbot, James Edinger, Aleksander Francki, Robert J. Hariri, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Neerav Padliya, Jennifer Paredes, Jia-Lun Wang
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Publication number: 20160129048Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: ApplicationFiled: June 10, 2015Publication date: May 12, 2016Applicant: ANTHROGENESIS CORPORATIONInventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert Hariri
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Patent number: 9078898Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: GrantFiled: February 14, 2014Date of Patent: July 14, 2015Assignee: Anthrogenesis CorporationInventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Publication number: 20150037316Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: ApplicationFiled: June 6, 2014Publication date: February 5, 2015Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Publication number: 20140377230Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: ApplicationFiled: February 14, 2014Publication date: December 25, 2014Applicant: Anthrogenesis CorporationInventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Patent number: 8895256Abstract: The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.Type: GrantFiled: May 17, 2012Date of Patent: November 25, 2014Assignee: Anthrogenesis CorporationInventors: Casper Paludan, James Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri
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Patent number: 8691217Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: GrantFiled: May 24, 2012Date of Patent: April 8, 2014Assignee: Anthrogenesis CorporationInventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Patent number: 8591883Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: GrantFiled: May 16, 2012Date of Patent: November 26, 2013Assignee: Anthrogenesis CorporationInventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Publication number: 20130028871Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: ApplicationFiled: May 16, 2012Publication date: January 31, 2013Inventors: James EDINGER, Qian YE, Jai-Lun WANG, Robert J. HARIRI
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Publication number: 20130022581Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: ApplicationFiled: May 24, 2012Publication date: January 24, 2013Inventors: James EDINGER, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Publication number: 20120225096Abstract: The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.Type: ApplicationFiled: May 17, 2012Publication date: September 6, 2012Inventors: Casper Paludan, James Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri
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Patent number: 8202703Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: GrantFiled: July 30, 2010Date of Patent: June 19, 2012Assignee: Anthrogenesis CorporationInventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Publication number: 20120122215Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: ApplicationFiled: October 18, 2011Publication date: May 17, 2012Inventors: James Edinger, Qian Ye, Jia-Lun Wang, Robert J. Hariri
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Publication number: 20100297689Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.Type: ApplicationFiled: July 30, 2010Publication date: November 25, 2010Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
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Publication number: 20100183571Abstract: The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.Type: ApplicationFiled: January 14, 2010Publication date: July 22, 2010Applicant: ANTHROGENESIS CORPORATIONInventors: Casper PALUDAN, James EDINGER, Ryhor HARBACHEUSKI, RoseAnn MURRAY, Robert J. HARIRI