Patents by Inventor James Edinger

James Edinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230142803
    Abstract: Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.
    Type: Application
    Filed: November 16, 2022
    Publication date: May 11, 2023
    Applicant: Celularity Inc.
    Inventors: Xiaokui ZHANG, Ivana DJURETIC, Lin KANG, Vanessa VOSKINARIAN-BERSE, Bhavani STOUT, Robert J. HARIRI, Wolfgang HOFGARTNER, James EDINGER, Eric LAW, Vladimer JANKOVIC
  • Publication number: 20220251104
    Abstract: Disclosed herein are new aromatic compounds, compositions that include one or more aromatic compounds, and methods of synthesizing the same. Also disclosed herein are methods of increasing and/or expanding cells, including stem cells, hematopoietic stem cells, progenitor cells, and placenta or cord blood-derived cells, with one or more compounds or compositions described herein. Also disclosed herein are methods of increasing and/or expanding differentiated hematopoietic cells with one or more compounds or compositions described herein.
    Type: Application
    Filed: November 29, 2019
    Publication date: August 11, 2022
    Applicant: Celularity Inc.
    Inventors: Robert J. HARIRI, Xiaokui ZHANG, James EDINGER
  • Publication number: 20210095258
    Abstract: The present invention provides an induced pluripotent stem (iPS) cell, or population of iPS cells, wherein the cell or cells giving rise to the iPS cell(s) are obtained from human postpartum tissue or cells, wherein the iPS cell(s) have increased levels of one or more factors selected from Group I: an Oct family member, a Sox family member, a Klf family member, a Myc family member, Nanog, Lin28, and combinations thereof. The present invention also provides differentiated cells derived from the cells of the invention and compositions, including pharmaceutical compositions comprising the cells of the invention. The invention further provides uses of the cells of the invention, e.g., in the treatment of a subject suffering from a disease of disorder. The invention additionally provides methods of generating iPS cell(s) from postpartum tissue, such as the cells of the invention.
    Type: Application
    Filed: February 22, 2019
    Publication date: April 1, 2021
    Applicant: Celularity Inc.
    Inventors: James EDINGER, Robert J. HARIRI, Sourav SINHA, Xiaokui ZHANG
  • Patent number: 10383897
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: August 20, 2019
    Assignee: Celularity, Inc.
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert Hariri
  • Publication number: 20180346877
    Abstract: Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.
    Type: Application
    Filed: October 14, 2016
    Publication date: December 6, 2018
    Applicant: CELULARITY, INC.
    Inventors: Xiaokui ZHANG, Ivana DJURETIC, Lin KANG, Vanessa VOSKINARIAN-BERSE, Bhavani STOUT, Robert J. HARIRI, Wolfgang HOFGARTNER, James EDINGER, Eric LAW, Vladimir JANKOVIC
  • Publication number: 20180071343
    Abstract: Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.
    Type: Application
    Filed: November 16, 2017
    Publication date: March 15, 2018
    Applicant: Celularity, Inc.
    Inventors: Stewart Abbot, James Edinger, Aleksander Francki, Robert J. Hariri, Vladimir Jankovic, Aleksandr Kaplunovsky, Kristen Labazzo, Eric Law, Neerav Padliya, Jennifer Paredes, Jia-Lun Wang
  • Publication number: 20160129048
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Application
    Filed: June 10, 2015
    Publication date: May 12, 2016
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert Hariri
  • Patent number: 9078898
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: July 14, 2015
    Assignee: Anthrogenesis Corporation
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Publication number: 20150037316
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Application
    Filed: June 6, 2014
    Publication date: February 5, 2015
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Publication number: 20140377230
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Application
    Filed: February 14, 2014
    Publication date: December 25, 2014
    Applicant: Anthrogenesis Corporation
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Patent number: 8895256
    Abstract: The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: November 25, 2014
    Assignee: Anthrogenesis Corporation
    Inventors: Casper Paludan, James Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri
  • Patent number: 8691217
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Grant
    Filed: May 24, 2012
    Date of Patent: April 8, 2014
    Assignee: Anthrogenesis Corporation
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Patent number: 8591883
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: November 26, 2013
    Assignee: Anthrogenesis Corporation
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Publication number: 20130028871
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Application
    Filed: May 16, 2012
    Publication date: January 31, 2013
    Inventors: James EDINGER, Qian YE, Jai-Lun WANG, Robert J. HARIRI
  • Publication number: 20130022581
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Application
    Filed: May 24, 2012
    Publication date: January 24, 2013
    Inventors: James EDINGER, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Publication number: 20120225096
    Abstract: The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.
    Type: Application
    Filed: May 17, 2012
    Publication date: September 6, 2012
    Inventors: Casper Paludan, James Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri
  • Patent number: 8202703
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: June 19, 2012
    Assignee: Anthrogenesis Corporation
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Publication number: 20120122215
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Application
    Filed: October 18, 2011
    Publication date: May 17, 2012
    Inventors: James Edinger, Qian Ye, Jia-Lun Wang, Robert J. Hariri
  • Publication number: 20100297689
    Abstract: The present invention provides placental stem cells and placental stem cell populations, and methods of culturing, proliferating and expanding the same. The invention also provides methods of differentiating the placental stem cells. The invention further provides methods of using the placental stem cells in assays and for transplanting.
    Type: Application
    Filed: July 30, 2010
    Publication date: November 25, 2010
    Inventors: James Edinger, Qian Ye, Jai-Lun Wang, Robert J. Hariri
  • Publication number: 20100183571
    Abstract: The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.
    Type: Application
    Filed: January 14, 2010
    Publication date: July 22, 2010
    Applicant: ANTHROGENESIS CORPORATION
    Inventors: Casper PALUDAN, James EDINGER, Ryhor HARBACHEUSKI, RoseAnn MURRAY, Robert J. HARIRI