Patents by Inventor James Edward Dowling

James Edward Dowling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical Compounds 251
    Publication number: 20150051185
    Abstract: The invention relates to chemical compounds of formula I, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.
    Type: Application
    Filed: July 24, 2014
    Publication date: February 19, 2015
    Applicant: AstraZeneca AB
    Inventors: Leslie DAKIN, James Edward DOWLING, Michelle Laurae LAMB, Jon READ, Qibin SU, XiaoLan ZHENG
  • Chemical compounds 251
    Patent number: 8901307
    Abstract: The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: December 2, 2014
    Assignee: AstraZeneca AB
    Inventors: Leslie Dakin, James Edward Dowling, Michelle Lamb, Jon Read, Xiaolan Zheng
  • CHEMICAL COMPOUNDS 251
    Publication number: 20110218182
    Abstract: The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.
    Type: Application
    Filed: July 2, 2009
    Publication date: September 8, 2011
    Applicant: ASTRAZENECA AB
    Inventors: Leslie Dakin, James Edward Dowling, Michelle Lamb, Jon Read, Qibin Su, Xiaolan Zheng