Patents by Inventor James Erdei

James Erdei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amino-5-[4-(difluoromehtoxy)phenyl]-5-phenylimidazolone compounds for the inhibition of beta-secretase
    Publication number: 20070072925
    Abstract: The present invention provides a 2-amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: September 25, 2006
    Publication date: March 29, 2007
    Applicant: Wyeth
    Inventors: Michael Malamas, James Erdei, William Fobare, Dominick Quagliato, Schuyler Antane, Albert Robichaud
  • Cycloalkyl amino-hydantoin compounds and use thereof for beta-secretase modulation
    Publication number: 20070027199
    Abstract: The present invention provides a 2-amino-5-cycloalkyl-hydantoin compound of formula I The present invention also provides methods and compositions for the inhibition of ?-secretase (BACE) and the treatment of ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: July 28, 2006
    Publication date: February 1, 2007
    Applicant: Wyeth
    Inventors: Michael Malamas, Iwan Gunawan, James Erdei, Pawel Nowak, Joseph Stock, Yinfa Yan
  • Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for beta-secretase modulation
    Publication number: 20070004786
    Abstract: The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles
    Type: Application
    Filed: June 29, 2006
    Publication date: January 4, 2007
    Applicant: Wyeth
    Inventors: Michael Malamas, Ping Zhou, William Fobare, William Solvibile, Iwan Gunawan, James Erdei, Yinfa Yan, Patrick Andrae, Dominick Quagliato
  • Amino-imidazolones for the inhibition of beta-secretase
    Publication number: 20060160828
    Abstract: The present invention provides an amino-imidazolone compound of formula I Also provided are compositions and methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: January 13, 2006
    Publication date: July 20, 2006
    Applicant: Wyeth
    Inventors: Michael Malamas, James Erdei, Iwan Gunawan, Pawel Nowak, Boyd Harrison
  • Diphenylimidazopyrimidine and -imidazole amines as inhibitors of beta-secretase
    Publication number: 20050282826
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated ?-amyloid deposits or ?-amyloid levels in a patient.
    Type: Application
    Filed: June 15, 2005
    Publication date: December 22, 2005
    Applicant: Wyeth
    Inventors: Michael Malamas, James Erdei, Iwan Gunawan, Keith Barnes, Matthew Johnson, Yu Hui
  • Amino-5,5-diphenylimidazolone derivatives for the inhibition of beta-secretase
    Publication number: 20050282825
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated ?-amyloid deposits or ?-amyloid levels in a patient.
    Type: Application
    Filed: June 15, 2005
    Publication date: December 22, 2005
    Applicant: Wyeth
    Inventors: Michael Malamas, James Erdei, Iwan Gunawan, Ping Zhou, Yinfa Yan, Dominick Quagliato