Patents by Inventor James Eric Gouaux

James Eric Gouaux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GluR2 receptor modulators
    Publication number: 20090270508
    Abstract: The present invention provides for compositions and methods for modulating the GluR2 receptor. It is based, at least in part, on the discovery, by X-ray crystallography, that a known GluR2 agonist binds to the receptor in two different orientations, thereby diminishing its potency. The present invention provides for structural alternatives in which alternative binding possibilities are substantially eliminated.
    Type: Application
    Filed: January 30, 2009
    Publication date: October 29, 2009
    Inventors: James Eric Gouaux, Langzhou Song, Yuli Xie, Donald W. Landry
  • Vectors And Methods For Identifying Proteins Amenable To Crystallization
    Publication number: 20090104645
    Abstract: The present invention provides for methods, systems and materials that may be used to identify and select proteins that are amenable to crystallization. While previous methods of screening proteins for crystallization required at least microgram quantities of purified protein, the inventive method can be practiced using nanogram quantities of unpurified protein.
    Type: Application
    Filed: August 7, 2008
    Publication date: April 23, 2009
    Applicant: The Trustees Of Columbia University In The City Of New York
    Inventors: James Eric Gouaux, Toshimitsu Kawate