Patents by Inventor James F. Antaki

James F. Antaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130276615
    Abstract: The present invention provides methods and devices for attenuating sound emanating from a harmonica when played while practicing or performing by a player. The methods and devices include a sound blocking and reflecting means and, optionally, a sound absorbing means.
    Type: Application
    Filed: April 19, 2013
    Publication date: October 24, 2013
    Inventor: James F. Antaki
  • Patent number: 8445192
    Abstract: The present invention provides a method and device for detecting and quantifying the concentration of magnetic-responsive micro-beads dispersed in a liquid sample. Also provided is a method and microfluidic immunoassay pScreen™ device for detecting and quantifying the concentration of an analyte in a sample medium by using antigen-specific antibody-coated magnetic-responsive micro-beads. The methods and devices of the present invention have broad applications for point-of-care diagnostics by allowing quantification of a large variety of analytes, such as proteins, protein fragments, antigens, antibodies, antibody fragments, peptides, RNA, RNA fragments, functionalized magnetic micro-beads specific to CD4+, CD8+ cells, malaria-infected red blood cells, cancer cells, cancer biomarkers such as prostate specific antigen and other cancer biomarkers, viruses, bacteria, and other pathogenic agents, with the sensitivity, specificity and accuracy of bench-top laboratory-based assays.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: May 21, 2013
    Assignee: Carnegie Mellon University
    Inventors: Alberto Gandini, James F. Antaki
  • Publication number: 20130078620
    Abstract: The present invention provides a method and device for detecting and quantifying the concentration of magnetic-responsive micro-beads dispersed in a liquid sample. Also provided is a method and microfluidic immunoassay pScreen™ device for detecting and quantifying the concentration of an analyte in a sample medium by using antigen-specific antibody-coated magnetic-responsive micro-beads. The methods and devices of the present invention have broad applications for point-of-care diagnostics by allowing quantification of a large variety of analytes, such as proteins, protein fragments, antigens, antibodies, antibody fragments, peptides, RNA, RNA fragments, functionalized magnetic micro-beads specific to CD4+, CD8+ cells, malaria-infected red blood cells, cancer cells, cancer biomarkers such as prostate specific antigen and other cancer biomarkers, viruses, bacteria, and other pathogenic agents, with the sensitivity, specificity and accuracy of bench-top laboratory-based assays.
    Type: Application
    Filed: November 26, 2012
    Publication date: March 28, 2013
    Inventors: Alberto Gandini, James F. Antaki
  • Publication number: 20130078615
    Abstract: The present invention provides a method and device for detecting and quantifying the concentration of magnetic-responsive micro-beads dispersed in a liquid sample. Also provided is a method and microfluidic immunoassay pScreen™ device for detecting and quantifying the concentration of an analyte in a sample medium by using antigen-specific antibody-coated magnetic-responsive micro-beads. The methods and devices of the present invention have broad applications for point-of-care diagnostics by allowing quantification of a large variety of analytes, such as proteins, protein fragments, antigens, antibodies, antibody fragments, peptides, RNA, RNA fragments, functionalized magnetic micro-beads specific to CD4+, CD8+cells, malaria-infected red blood cells, cancer cells, cancer biomarkers such as prostate specific antigen and other cancer biomarkers, viruses, bacteria, and other pathogenic agents, with the sensitivity, specificity and accuracy of bench-top laboratory-based assays.
    Type: Application
    Filed: August 21, 2012
    Publication date: March 28, 2013
    Inventors: Alberto Gandini, James F. Antaki
  • Publication number: 20120143141
    Abstract: Cannula assemblies and related methods are provided. In accordance with one embodiment, a cannula assembly includes a tubular structure coupled with a flange assembly. The flange assembly includes a plurality of wireform loops disposed in a circumferential, woven pattern about an end of the tubular structure. The flange assembly is configured to exhibit a first, collapsed state wherein the plurality of wireform loops extend substantially axially from the tubular structure, and a second, expanded state wherein the plurality of wireform loops extend in a direction having a substantial radial component relative to the tubular structure. In another embodiment, a cannula assembly includes a conformal flange coupled with a tubular structure, wherein the tubular structure extends both distally and proximally of the flange.
    Type: Application
    Filed: August 3, 2011
    Publication date: June 7, 2012
    Inventors: Josiah E. Verkaik, James F. Antaki, John Alexander Martin
  • Publication number: 20120130255
    Abstract: Medical device or instrument for diagnosing pressure ulcers using optical reflectance spectroscopy. The device may comprise a tip and a controller. The tip is pressed against the skin of the patient and collects the optical reflectance data. The controller processes the data to determine whether there exists a pressure ulcer and, if there is one, its depth. The tip may also include a pressure sensor for sensing the pressure at which the tip is applied to the patient's skin.
    Type: Application
    Filed: January 30, 2012
    Publication date: May 24, 2012
    Applicants: University of Pittsburgh, Carnegie Mellon University
    Inventors: Sanna Gaspard, Mei Siegel, Todd M. Przybycien, James F. Antaki, David M. Brienza, Mark B. Friedman
  • Publication number: 20120036980
    Abstract: The invention provides an apparatus and method for notating music for a harmonica. The apparatus incorporates a vertical staff in which vertical lines or tracks represent individual notes, the length of which represents duration of the note, and the horizontal location represents the physical location of the corresponding hole in a harmonica. The invention provides a rapid means of learning to play a harmonica and, for experienced players, provides a means for sight reading a new piece of music. The invention further provides ways of representing the dynamics of both pitch and loudness and a convenient way to manually transcribe musical selection for archival purposes.
    Type: Application
    Filed: August 12, 2011
    Publication date: February 16, 2012
    Inventor: James F. Antaki
  • Patent number: 8116838
    Abstract: Medical device or instrument for diagnosing pressure ulcers using optical reflectance spectroscopy. The device may comprise a tip and a controller. The tip is pressed against the skin of the patient and collects the optical reflectance data. The controller processes the data to determine whether there exists a pressure ulcer and, if there is one, its depth. The tip may also include a pressure sensor for sensing the pressure at which the tip is applied to the patient's skin.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: February 14, 2012
    Assignee: Carnegie Mellon University
    Inventors: Sanna Gaspard, Mel Siegel, Todd M. Przybycien, James F. Antaki, David M. Brienza, Mark B. Friedman
  • Publication number: 20110303072
    Abstract: A system for altering the pitch produced by a reed of a reeded instrument. The system comprises a reed having a first portion structured to be coupled to the instrument and a second portion generally free to vibrate and a magnet adjustably disposed adjacent the reed. The reed comprises a magnetic material.
    Type: Application
    Filed: June 15, 2010
    Publication date: December 15, 2011
    Inventor: James F. Antaki
  • Publication number: 20110237863
    Abstract: A magnetically-levitated blood pump with an optimization method that enables miniaturization and supercritical operation. The blood pump includes an optimized annular blood gap that increases blood flow and also provides a reduction in bearing stiffness among the permanent magnet bearings. Sensors are configured and placed optimally to provide space savings for the motor and magnet sections of the blood pump. Rotor mass is increased by providing permanent magnet placement deep within the rotor enabled by a draw rod configuration.
    Type: Application
    Filed: September 24, 2009
    Publication date: September 29, 2011
    Applicant: WORLDHEART, INC.
    Inventors: Michael R. Ricci, James F. Antaki, Josiah E. Verkaik, David B. Paden, Shaun T. Snyder, Bradley E. Paden
  • Publication number: 20090234206
    Abstract: Medical device or instrument for diagnosing pressure ulcers using optical reflectance spectroscopy. The device may comprise a tip and a controller. The tip is pressed against the skin of the patient and collects the optical reflectance data. The controller processes the data to determine whether there exists a pressure ulcer and, if there is one, its depth. The tip may also include a pressure sensor for sensing the pressure at which the tip is applied to the patient's skin.
    Type: Application
    Filed: November 26, 2008
    Publication date: September 17, 2009
    Inventors: Sanna Gaspard, Mei Siegel, Todd M. Prbycien, James F. Antaki, David M. Brienza, Mark B. Friedman
  • Patent number: 7338521
    Abstract: A low profile pump inlet for an implantable blood pump is disclosed. The low profile pump inlet has an inflow diffuser for attachment to a conduit bearing an inflow of a fluid such as blood and an outflow orifice in fluid connection with the diffuser. The outflow orifice is configured to direct the fluid from the diffuser into a pump such as an implantable blood pump. The low profile pump inlet helps to suppress the effects of upstream pipe bends on the blood traveling through the inlet. The inlet thus provides a flow having a substantially uniform velocity profile into the blood pump.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: March 4, 2008
    Assignee: World Heart, Inc.
    Inventors: James F. Antaki, Jed C. Ludlow, Scott D. Miles
  • Publication number: 20030233144
    Abstract: A low profile pump inlet for an implantable blood pump is disclosed. The low profile pump inlet has an inflow diffuser for attachment to a conduit bearing an inflow of a fluid such as blood and an outflow orifice in fluid connection with the diffuser. The outflow orifice is configured to direct the fluid from the diffuser into a pump such as an implantable blood pump. The low profile pump inlet helps to suppress the effects of upstream pipe bends on the blood traveling through the inlet. The inlet thus provides a flow having a substantially uniform velocity profile into the blood pump.
    Type: Application
    Filed: June 13, 2002
    Publication date: December 18, 2003
    Inventors: James F. Antaki, Jed C. Ludlow, Scott D. Miles
  • Patent number: 6635814
    Abstract: Harmonica structures designed for enhancing harmonica play are disclosed. In one aspect, a reed comb is provided with a common bridge having reeds formed integrally therewith. The reed plate has a plurality of reed slots formed therein and is adapted to receive the reeds of the reed comb into corresponding slots formed in the reed plate. A stepped portion formed in the reed plate is adapted to receive a reed of the reed comb therein to permit substantial encasement of the reed within the reed slot. A key benefit of this arrangement is to resist leakage of air between the reed plate and the flanks of the reed during harmonica play. The reed plate can also include a first stepped portion upon which the roots of the reeds are positioned and a second stepped portion positioned adjacent to the tips of the reeds. Other structures are disclosed that include a radiused surface formed on a portion of the reed or on the surface of the reed slot in which the reed is positioned.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: October 21, 2003
    Inventor: James F. Antaki
  • Publication number: 20030078585
    Abstract: An apparatus for holding a first portion of a bone and a second portion of a bone together for the bone to heal. A method for holding a first portion of a bone and a second portion of a bone together for the bone to heal. A suture. A grommet for a bone. A method for securing a suture through a bone.
    Type: Application
    Filed: November 25, 2002
    Publication date: April 24, 2003
    Inventors: Greg A. Johnson, James F. Antaki, James A. Magovern, Matthew R. Frushell, Thomas David Will, John Andrew Holmes
  • Publication number: 20030023131
    Abstract: An apparatus and method for reducing backflow in a heart pump device are disclosed. In one configuration, a ventricular assist device (VAD) has a pump connected to a ventricle of the heart by an inflow cannula and to a blood vessel by an outflow cannula. The VAD is designed in such a manner that the overall reactance of the VAD is comparatively high, thereby reducing the incidence of time-varied flows, such as backflow, through the VAD. Resistance of the VAD to steady state flow may simultaneously be maintained below a threshold level to provide low-power operation. The desired reactance and resistance properties of the VAD may be obtained by adjusting the reactance and resistance of one or both of the cannulae. The reactance of a cannula may be set at the desired level by tuning one or more geometric characteristics of the cannula, including the bore diameter, length, cross sectional bore shape, and compliance of the cannula.
    Type: Application
    Filed: June 5, 2002
    Publication date: January 30, 2003
    Inventor: James F. Antaki
  • Patent number: 6485504
    Abstract: An apparatus for holding a first portion of a bone and a second portion of a bone together for the bone to heal. A method for holding a first portion of a bone and a second portion of a bone together for the bone to heal. A suture. A grommet for a bone. A method for securing a suture through a bone.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: November 26, 2002
    Inventors: Greg A. Johnson, James F. Antaki, James A. Magovern, Matthew R. Frushell, Thomas David Will, John Andrew Holmes
  • Patent number: 6447265
    Abstract: A rotary pump for pumping fluids through a patient having a housing with an internal region, a stator member and an impeller positioned within the housing and having impeller blades, wherein the impeller is magnetically suspended and rotated, and wherein the geometric configuration of the rotary pump is sized and proportioned to minimize stagnant and traumatic fluid flow within the rotary pump. The plurality of magnetic impeller blades are preferably rare earth, high-energy-density magnets selected from the group consisting of samarium cobalt and neodymium-iron-boron alloy.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: September 10, 2002
    Assignees: The University of Pittsburgh, The United States of America as represented by the United States National Aeronautics and Space Administration
    Inventors: James F. Antaki, Bradley Paden, Gregory Burgreen, Nelson Groom
  • Patent number: 6447266
    Abstract: A blood pump preferably has a magnetically suspended rotor that rotates within a housing. The rotor may rotate about a stator disposed within the housing. Radial magnetic bearings may be defined within the stator and the rotor in order to suspend the rotor. The radial magnetic bearings may be passive magnetic bearings that include permanent magnets disposed within the stator and the rotor or active magnetic bearings. The pump may further include an axial magnetic bearing that may be either a passive or an active magnetic bearing. A motor that drives the rotor may be disposed within the housing in order to more easily dissipate heat generated by the motor. A primary flow path is defined between the rotor and the stator, and a secondary flow path is defined between the stator and the rotor. Preferably, a substantial majority of blood passes through the primary flow path.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: September 10, 2002
    Assignees: University of Pittsburgh, The United States of America as represented by the United States National Aeronautics and Space Administration
    Inventors: James F. Antaki, Bradley Paden, Gregory Burgreen, Nelson J. Groom
  • Publication number: 20020069745
    Abstract: Harmonica structures designed for enhancing harmonica play are disclosed. In one aspect, a reed comb is provided with a common bridge having reeds formed integrally therewith. The reed plate has a plurality of reed slots formed therein and is adapted to receive the reeds of the reed comb into corresponding slots formed in the reed plate. A stepped portion formed in the reed plate is adapted to receive a reed of the reed comb therein to permit substantial encasement of the reed within the reed slot. A key benefit of this arrangement is to resist leakage of air between the reed plate and the flanks of the reed during harmonica play. The reed plate can also include a first stepped portion upon which the roots of the reeds are positioned and a second stepped portion positioned adjacent to the tips of the reeds. Other structures are disclosed that include a radiused surface formed on a portion of the reed or on the surface of the reed slot in which the reed is positioned.
    Type: Application
    Filed: January 28, 2002
    Publication date: June 13, 2002
    Inventor: James F. Antaki