Patents by Inventor James F. Kerwin, Jr.

James F. Kerwin, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazoles and related compounds as &agr;1A agonists
    Patent number: 6503935
    Abstract: Compounds having formula I: are useful in treating diseases prevented by or ameliorated with &agr;1A agonists. Also disclosed are &agr;1A agonist compositions and a method of activating &agr;1 adrenoceptors in a mammal.
    Type: Grant
    Filed: July 29, 1999
    Date of Patent: January 7, 2003
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Michael D. Meyer, James F. Kerwin, Jr., Mark W. Holladay, Albert Khilevich, Teodozyj Kolasa, Jeffrey Rohde, William A. Carroll
  • Benzopyranopyrrole and benzopyranopyridine .alpha.-1 adrenergic compounds
    Patent number: 6046207
    Abstract: The present invention relates to a compound of the formula and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are .alpha.-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 adrenoreceptors and treating BPH.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: April 4, 2000
    Inventors: Michael D. Meyer, Robert J. Altenbach, Fatima Z. Basha, William A. Carroll, Irene Drizin, James F. Kerwin, Jr., Michael D. Wendt, Anthony R. Haight, Weijiang Zhang
  • Benzopyranopyrrole and benzopyranopyridine .alpha.-1 adenergic compounds
    Patent number: 5891882
    Abstract: The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are .alpha.-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.
    Type: Grant
    Filed: November 21, 1997
    Date of Patent: April 6, 1999
    Assignee: Abbott Laboratories
    Inventors: Michael D. Meyer, Robert J. Altenbach, Fatima Z. Basha, William A. Carroll, Irene Drizin, James F. Kerwin, Jr., Michael D. Wendt
  • Adenosine kinase polypeptides
    Patent number: 5861294
    Abstract: The present invention provides an adenosine kinase protein having an identified structural formula. The identified protein or similar adenosine kinase proteins having residues as claimed and recited herein may be isolated and purified from natural sources or produced by recombinant DNA technology.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 19, 1999
    Assignee: Abbott Laboratories
    Inventors: Marlon Daniel Cowart, Donald N. Halbert, James F. Kerwin, Jr., Teresa McNally
  • Bicyclic substituted hexahydrobenz ?e! isoindole alpha-1 adrenergic antagonists
    Patent number: 5792767
    Abstract: The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are .alpha.-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: August 11, 1998
    Assignee: Abbott Laboratories
    Inventors: Michael D. Meyer, Robert J. Altenbach, Fatima Z. Basha, William A. Carroll, Irene Drizin, James F. Kerwin, Jr., Suzanne A. Lebold, Edmund L. Lee, John K. Pratt, Kevin B. Sippy, Karin R. Tietje, Diane M. Yamamoto
  • Tricyclic substituted hexahydrobenz [e]isoindole alpha-1 adrenergic antagonists
    Patent number: 5597823
    Abstract: The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an .alpha.-1 adrenergic antagonist and is useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 28, 1997
    Assignee: Abbott Laboratories
    Inventors: Michael D. Meyer, Robert J. Altenbach, Fatima Z. Basha, William A. Carroll, Irene Drizin, Steven W. Elmore, James F. Kerwin, Jr., Suzanne A. Lebold, Edmund L. Lee, Kevin B. Sippy, Karin R. Tietje, Michael D. Wendt
  • Bicyclic substituted hexahydrobenz[e]isoindole .alpha.-1 adrenergic antagonists
    Patent number: 5521181
    Abstract: The present invention relates to a compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are .alpha.-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: May 28, 1996
    Assignee: Abbott Laboratories
    Inventors: Michael D. Meyer, Robert J. Altenbach, William A. Carroll, Irene Drizin, Suzanne A. Lebold, Edmund L. Lee, Kevin B. Sippy, Karin R. Tietje, Diane M. Yamamoto, James F. Kerwin, Jr.
  • Amino acid analog CCK antagonists
    Patent number: 5346907
    Abstract: Analogs of CCK-tetrapeptides, which analogs have the formula ##STR1## wherein A, B, D, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are specifically defined, having activity as CCK antagonists, useful in the treatment or prevention of disorders of the gastrointestinal, central nervous, appetite regulating or pain regulating systems.
    Type: Grant
    Filed: February 16, 1993
    Date of Patent: September 13, 1994
    Assignee: Abbott Laboratories
    Inventors: James F. Kerwin, Jr., Mark W. Holladay, Michael J. Bennett