Patents by Inventor James Fells

James Fells has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220144837
    Abstract: The present invention relates to Compounds of Formula I and Ia and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, X, A and B are as defined herein. The present invention also relates to compositions comprising at least one compound of Formula I or Ia, and methods of using the compounds of Formula I or Ia for treating or preventing HIV infection in a subject.
    Type: Application
    Filed: March 16, 2020
    Publication date: May 12, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Wensheng Yu, Joseph A. Kozlowski, Dane James Clausen, Jian Liu, James Fells
  • Publication number: 20220119351
    Abstract: The present disclosure relates to compounds of formula (I) that are useful as modulators of 7? nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation.
    Type: Application
    Filed: April 27, 2020
    Publication date: April 21, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Ian M. Bell, Brian T. Campbell, Brendan M. Crowley, James Fells, Kenneth J. Leavitt, Anthony J. Roecker, Andrew John Harvey, Belinda C. Huff, Dharam Paul, Christophe Morice, Christophe Joseph, Patrick Bazzini, Jean-Marie Contreras, Fabrice Garrido, Aurelie Witzel
  • Publication number: 20180189460
    Abstract: Disclosed is a five-feature pharmacophore model of LPA2 receptor specific agonists. Compounds may be identified as agonists of the LPA2 receptor using the five-feature pharmacophore model.
    Type: Application
    Filed: November 19, 2017
    Publication date: July 5, 2018
    Inventors: Renukadevi Patil, James Fells, Duane Miller, Gabor Tigyi
  • Publication number: 20170216658
    Abstract: The Companion is an exercise mat that lies on the floor beneath the TRX Suspension Training System (TRX), and includes visual and/or tactile markings (such as numeric measurements) to indicate the proper placement of feet when exercising with the TRX. The mat facilitates correct placement of the feet in terms of proximity to the TRX anchor point to ensure safe and effective exercise technique and the proper degree of resistance as it pertains to body weight. Contours or ridges may also be provided on the mat in order to facilitate proper foot positioning.
    Type: Application
    Filed: February 2, 2016
    Publication date: August 3, 2017
    Inventor: Brandon James Fell
  • Patent number: 9056835
    Abstract: Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA2 receptor. Compounds of the invention comprise non-lipid benzoic acid derivatives.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: June 16, 2015
    Assignee: The University of Tennessee Research Foundation
    Inventors: Renukadevi Patil, James Fells, Duane D. Miller, Gabor Tigyi
  • Publication number: 20140206714
    Abstract: Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA2 receptor. Compounds of the invention comprise non-lipid benzoic acid derivatives. Further disclosed is a pharmacophore of LPA2 receptor.
    Type: Application
    Filed: March 21, 2014
    Publication date: July 24, 2014
    Applicant: University of Tennessee Research Foundation
    Inventors: Renukadevi Patil, James Fells, Duane Miller, Gabor Tigyi
  • Publication number: 20140057936
    Abstract: Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA2 receptor. Compounds of the invention comprise non-lipid benzoic acid derivatives.
    Type: Application
    Filed: August 27, 2013
    Publication date: February 27, 2014
    Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Renukadevi Patil, James Fells, Duane D. Miller, Gabor Tigyi
  • Patent number: D765446
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: September 6, 2016
    Inventor: Eric James Fell