Abstract: An autonomous surface cleaning apparatus includes a body including a chassis and an outer shell mounted to the chassis, a drive system carried by the body, a cleaning assembly projecting forward beyond a front surface of the outer shell, the cleaning assembly having a generally planar front surface, and a forward bumper mounted to the front surface of the cleaning assembly. The apparatus further includes a plurality of forwardmost contact sensors disposed behind the forward bumper and arranged to detect displacement of the forward bumper relative to the cleaning assembly, a first plurality of shell contact sensors each being arranged to detect longitudinal displacement of the outer shell relative, and a second plurality of shell contact sensors each being arranged to detect lateral displacement of the outer shell relative to both the chassis and the cleaning assembly.

Abstract: The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer.

Abstract: The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer.

Abstract: The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer.

Abstract: The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer.

Abstract: The present invention relates to compositions comprising TWIST signaling inhibitors and optionally one or more anti-cancer agents, and methods of using the compositions for the treatment of cancer.

Abstract: An electrode array (30) which is able to be inserted to a desired depth within the cochlea to provide useful percepts for the recipient which will also preferably not cause damage to the sensitive structures of the cochlea. The electrode array (30) is insertable through an opening in the cochlea and into at least the basal region of the cochlea and comprises an elongate carrier (31) having a proximal end, a distal end, and a plurality of electrodes (32) supported by the carrier at respective spaced locations thereon in a region between the proximal end and the distal end. A stabilizing collar (35) extends outwardly from the elongate carrier (31) at or adjacent a proximal end thereof and has an abutment surface adapted to abut a portion of the cochlea surface around the cochleostomy and at least substantially prevent movement of the carrier (31) following completion of insertion of the array (30) into the cochlea.

Abstract: An electrode array (30) which is able to be inserted to a desired depth within the cochlea to provide useful percepts for the recipient which will also preferably not cause damage to the sensitive structures of the cochlea. The electrode array (30) is insertable through an opening in the cochlea and into at least the basal region of the cochlea and comprises an elongate carrier (31) having a proximal end, a distal end, and a plurality of electrodes (32) supported by the carrier at respective spaced locations thereon in a region between the proximal end and the distal end. A stabilising collar (35) extends outwardly from the elongate carrier (31) at or adjacent a proximal end thereof and has an abutment surface adapted to abut a portion of the cochlea surface around the cochleostomy and at least substantially prevent movement of the carrier (31) following completion of insertion of the array (30) into the cochlea.

Abstract: An embodiment of the present invention takes masking effects into consideration when determining stimulations signals for neural stimulation. These masking effects may be modeled using user-specific models determined by taking measurements for an implant system of an implant recipient. Or, the model may correspond to a group of individuals sharing a common characteristic or the population as a whole. These models may be, for example, psycho-physical or electrophysiological models.

Abstract: An electrode array that is implantable within the inferior colliculus of the midbrain and/or other appropriate regions of the brain of an implantee and adapted to provide electrical stimulation thereto. The electrode array an elongate member having a plurality of electrodes mounted thereon in a longitudinal array. A delivery cannula for delivering the electrode array comprised of two half-pipes is also described.

Abstract: A sphincteric control system for controlling the function of a bodily organ, such as the bladder. The system comprises a first implanted sphincter (12) disposed about a portion of the bodily organ, a second implanted sphincter (13) disposed about a portion of the bodily organ, and a stimulator unit (20) that is adapted to apply electrical stimulation to each of the first and second implanted sphincters. One of the first or second implanted sphincters is made from a smooth muscle and the other of the first or second implanted sphincters is made from a striated muscle.

Abstract: An electrode array (30) which is able to be inserted to a desired depth within the cochlea to provide useful percepts for the recipient which will also preferably not cause damage to the sensitive structures of the cochlea. The electrode array (30) is insertable through an opening in the cochlea and into at least the basal region of the cochlea and comprises an elongate carrier (31) having a proximal end, a distal end, and a plurality of electrodes (32) supported by the carrier at respective spaced locations thereon in a region between the proximal end and the distal end. A stabilising collar (35) extends outwardly from the elongate carrier (31) at or adjacent a proximal end thereof and has an abutment surface adapted to abut a portion of the cochlea surface around the cochleostomy and at least substantially prevent movement of the carrier (31) following completion of insertion of the array (30) into the cochlea.

Abstract: An implanted device such as a cochlear implant system includes a housing containing stimulating pulse generating circuitry, and a plurality of electrodes external of the housing and receiving the pulses. Between the pulses, parasitic voltages may build up between the electrodes. In order to control the inrush current due to these parasitic voltages, multi-position switches are provided which selectively couple the electrodes to resistors selected to dissipate the voltages at a preselected maximum current to protect the body organs.

Abstract: A computerized airline flight reservation system simulator that allows air ravel carriers to simulate changes in flight schedules and predict the impact of those changes on a carrier's revenue. The simulator includes means for the input of host and other airline scheduled flight information which is used to build a global network of flight services offered on existing central reservation systems (CRS). The network is built according to CRS build and edit rules and simulates the screen display of reservation systems according to CRS display and sorting rules. The system simulates the screen presence on existing CRSs allowing the airline to predict the revenues derived from its present flight schedule and provides means to make proposed changes in its schedule and correspondingly see how such changes may impact revenues.

Abstract: A sealing means for permitting continuous passage of a web material through a gap in a wall separating two zones at different pressures whilst minimising the flow of air from one zone to the other, comprising a cylindrical rod passing through the gap, means for feeding the web material on to the rod in helical disposition on one side of the wall, means for removing the web material from the rod after the web material has passed through the gap to the other side of the wall, and sealing means fitted to the circumference of the gap so as to contact the web material as it passes through the gap, and the use of two such sealing means as an entrance to, and exit from, an apparatus the interior of which is to be maintained at a pressure less than atmospheric pressure, and in which apparatus the web material is to be given an appropriate treatment.