Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating images. In one aspect, a method includes: receiving an input text prompt including a sequence of text tokens in a natural language; processing the input text prompt using a text encoder neural network to generate a set of contextual embeddings of the input text prompt; and processing the contextual embeddings through a sequence of generative neural networks to generate a final output image that depicts a scene that is described by the input text prompt.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating images. In one aspect, a method includes: receiving an input text prompt including a sequence of text tokens in a natural language; processing the input text prompt using a text encoder neural network to generate a set of contextual embeddings of the input text prompt; and processing the contextual embeddings through a sequence of generative neural networks to generate a final output image that depicts a scene that is described by the input text prompt.

Abstract: A method includes receiving training data comprising a plurality of pairs of images. Each pair comprises a noisy image and a denoised version of the noisy image. The method also includes training a multi-task diffusion model to perform a plurality of image-to-image translation tasks, wherein the training comprises iteratively generating a forward diffusion process by predicting, at each iteration in a sequence of iterations and based on a current noisy estimate of the denoised version of the noisy image, noise data for a next noisy estimate of the denoised version of the noisy image, updating, at each iteration, the current noisy estimate to the next noisy estimate by combining the current noisy estimate with the predicted noise data, and determining a reverse diffusion process by inverting the forward diffusion process to predict the denoised version of the noisy image. The method additionally includes providing the trained diffusion model.

Abstract: Disclosed herein are systems and methods for efficient 3D structure estimation from images of a transmissive object, including cryo-EM images. The method generally comprises, receiving a set of 2D images of a target specimen from an electron microscope, carrying out a reconstruction technique to determine a likely molecular structure, and outputting the estimated 3D structure of the specimen. The described reconstruction technique comprises: establishing a probabilistic model of the target structure; optimizing using stochastic optimization to determine which structure is most likely; and, optionally utilizing importance sampling to minimize computational burden.

Abstract: Disclosed herein are systems and methods for efficient 3D structure estimation from images of a transmissive object, including cryo-EM images. The method generally comprises, receiving a set of 2D images of a target specimen from an electron microscope, carrying out a reconstruction technique to determine a likely molecular structure, and outputting the estimated 3D structure of the specimen. The described reconstruction technique comprises: establishing a probabilistic model of the target structure; optimizing using stochastic optimization to determine which structure is most likely; and, optionally utilizing importance sampling to minimize computational burden.

Abstract: Disclosed herein are systems and methods for efficient 3D structure estimation from images of a transmissive object, including cryo-EM images. The method generally comprises, receiving a set of 2D images of a target specimen from an electron microscope, carrying out a reconstruction technique to determine a likely molecular structure, and outputting the estimated 3D structure of the specimen. The described reconstruction technique comprises: establishing a probabilistic model of the target structure; optimizing using stochastic optimization to determine which structure is most likely; and, optionally utilizing importance sampling to minimize computational burden.

Abstract: A system and a method for image alignment between at least two images to a three-dimensional model. The method including: determining a lower bound and an upper bound of an acceptable likelihood of mismatch between the at least two images; evaluating the likelihood of mismatch between the at least two images over a set of poses (r), shifts (t), or both poses (r) and shifts (t); and discarding those evaluations resulting beyond the lower bound and upper bound.

Abstract: A system and a method for image alignment between at least two images to a three-dimensional model. The method including: determining a lower bound and an upper bound of an acceptable likelihood of mismatch between the at least two images; evaluating the likelihood of mismatch between the at least two images over a set of poses (r), shifts (t), or both poses (r) and shifts (t); and discarding those evaluations resulting beyond the lower bound and upper bound.

Abstract: A system and a method for image alignment between at least two images to a three-dimensional model. The method including: determining a lower bound and an upper bound of an acceptable likelihood of mismatch between the at least two images; evaluating the likelihood of mismatch between the at least two images over a set of poses (r), shifts (t), or both poses (r) and shifts (t); and discarding those evaluations resulting beyond the lower bound and upper bound.

Abstract: A system and a method for image alignment between at least two images to a three-dimensional model. The method including: determining a lower bound and an upper bound of an acceptable likelihood of mismatch between the at least two images; evaluating the likelihood of mismatch between the at least two images over a set of poses (r), shifts (t), or both poses (r) and shifts (t); and discarding those evaluations resulting beyond the lower bound and upper bound.

Abstract: Disclosed herein are systems and methods for efficient 3D structure estimation from images of a transmissive object, including cryo-EM images. The method generally comprises, receiving a set of 2D images of a target specimen from an electron microscope, carrying out a reconstruction technique to determine a likely molecular structure, and outputting the estimated 3D structure of the specimen. The described reconstruction technique comprises: establishing a probabilistic model of the target structure; optimizing using stochastic optimization to determine which structure is most likely; and, optionally utilizing importance sampling to minimize computational burden.

Abstract: An improved design of interlocking components is disclosed. The components may be used to form arbitrary solid shells with complex curvatures, including, for example, three dimensional puzzle games.

Abstract: A method, computer program product and database management system for recording a change to a database in a log including a plurality of log records. The database management system is capable of concurrently processing and logging multiple database changes. A tracking descriptor is used in conjunction with first and second identifiers for each log record to reduce the amount of logic executed using latching for each log record.