Patents by Inventor James Folmer

James Folmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxadiazole derivatives and their use as metabotropic glutamate receptor potentiators 842
    Patent number: 8377939
    Abstract: Compounds of Formula I: wherein R1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: February 19, 2013
    Assignee: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Oxadiazole derivatives and their use as metabotropic glutamate receptor potentiators—842
    Patent number: 8377940
    Abstract: Compounds of Formula (I) wherein R1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: February 19, 2013
    Assignee: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators—286
    Patent number: 8148372
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: April 3, 2012
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators
    Patent number: 7888353
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: February 15, 2011
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • METABOTROPIC GLUTAMATE RECEPTOR ISOXAZOLE LIGANDS AND THEIR USE AS POTENTIATORS
    Publication number: 20100324044
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 26, 2010
    Publication date: December 23, 2010
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators - 286
    Publication number: 20100317662
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Metabotropic Glutamate Receptor Oxadiazole Ligands and Their Use as Potentiators
    Publication number: 20100280082
    Abstract: Compounds of Formula (I) wherein R1, R2, R3 R4 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 5, 2008
    Publication date: November 4, 2010
    Applicant: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Oxadiazole Derivatives and Their Use as Metabotropic Glutamate Receptor Potentiators - 842
    Publication number: 20100267740
    Abstract: Compounds of Formula (I) wherein R1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 5, 2008
    Publication date: October 21, 2010
    Applicant: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Metabotropic glutamate receptor oxadiazole ligands and their use as potentiators 841
    Patent number: 7799792
    Abstract: Compounds of Formula I: wherein R1, R2, R3, R4 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: September 21, 2010
    Assignee: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators 286
    Patent number: 7790760
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: September 7, 2010
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Metabotropic glutamate receptor isoxazole ligands and their use as potentiators—286
    Patent number: 7781434
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: August 24, 2010
    Assignee: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M Hunter, Scott Throner
  • Spirocyclopropyl Piperidine Derivatives
    Publication number: 20100168105
    Abstract: Disclosed herein is at least one piperidine derivative, at least one pharmaceutical composition comprising at least one piperidine derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith
    Type: Application
    Filed: May 23, 2008
    Publication date: July 1, 2010
    Inventors: Peter Bernstein, Dean Brown, Joseph Cacciola, Phil Edwards, James Folmer, Thierry Groblewski, Mark Sylvester, Steven Wesolowski
  • Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators - 286
    Publication number: 20100022545
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: October 8, 2009
    Publication date: January 28, 2010
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators 286
    Publication number: 20090306158
    Abstract: Compounds in accord with Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 3, 2009
    Publication date: December 10, 2009
    Applicant: AstraZeneca AB
    Inventors: Joseph Cacciola, James Empfield, James Folmer, Angela M. Hunter, Scott Throner
  • Oxadiazole Derivatives and Their Use as Metabotropic Glutamate Receptor Potentiators 842
    Publication number: 20080306077
    Abstract: Compounds of Formula I: wherein R1 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 6, 2008
    Publication date: December 11, 2008
    Applicant: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Metabotropic Glutamate Receptor Oxadiazole Ligands and Their Use as Potentiators 841
    Publication number: 20080306088
    Abstract: Compounds of Formula I: wherein R1, R2, R3, R4 and Q are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: June 6, 2008
    Publication date: December 11, 2008
    Applicant: AstraZeneca AB
    Inventors: Joshua Clayton, Ian Egle, James Empfield, James Folmer, Methvin Isaac, Fupeng Ma, Abdelmalik Slassi
  • Piperidine Derivatives as Histamine H3 Receptor Ligands
    Publication number: 20080064706
    Abstract: Compounds of formula: wherein Ar1 and Q are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the treatment of depression.
    Type: Application
    Filed: July 27, 2005
    Publication date: March 13, 2008
    Applicant: AstraZeneca AB
    Inventors: James Folmer, Simon Hunt, Peter Hamley, Steven Wesolowski
  • Novel Piperidine Derivatives as Histamine H3 Receptor Ligands for Treatment of Depression
    Publication number: 20070249618
    Abstract: Compounds of formula (I) wherein Ar1 and Q are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the treatment of depression.
    Type: Application
    Filed: July 27, 2005
    Publication date: October 25, 2007
    Applicant: AstraZeneca AB
    Inventors: James Folmer, Simon Hunt, Peter Hamley, Steven Wesolowski
  • Novel piperidine derivative for the treatment of depression
    Publication number: 20070191358
    Abstract: Compounds of formula: (chemical formula to be inserted here—please see paper copy) wherein Arl is as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the treatment of depression.
    Type: Application
    Filed: July 27, 2005
    Publication date: August 16, 2007
    Applicant: AstraZeneca AB
    Inventors: James Folmer, Simon Hunt, Peter Hamley, Steven Wesolowski
  • Estrogen Receptor-beta ligands
    Publication number: 20050043350
    Abstract: A method for treating a disease associated with the estrogen receptor-?, comprising the step of administiering a therapeutically-effective amount of a compound that satifies the equation: Ki?A/Ki?A>25, optionally having general structure (I).
    Type: Application
    Filed: October 10, 2001
    Publication date: February 24, 2005
    Inventors: Bernard Barlaam, James Folmer, Timothy Piser