Abstract: An injection device includes a drive spring within the housing, a first drive component that transfers drive from the drive spring to a plunger disposed within a medicament container, and a damper concentrically arranged with respect to the first drive component. The damper is longitudinally fixed relative to the housing. The first drive component moves along the longitudinal axis relative to the damper under the influence of the drive spring. The damper frictionally engages a surface of the first drive component during movement of the drive component relative to the damper. A method of manufacturing the injection device is also described.

Abstract: A microfluidic device may have at least one inlet channel; a microfluidic channel having a first portion fluidly connected to the at least one inlet channel; and at least one outlet channel fluidly connected to a second portion of the microfluidic channel, wherein the microfluidic channel has a plurality of dimples extending away from an axis of the microfluidic channel. The at least one inlet channel includes a first inlet channel and a second inlet channel, and/or the at least one outlet channel includes a first outlet channel and a second outlet channel. In some embodiments, the plurality of dimples may be configured to separate nanoparticles of different sizes to the first outlet channel and the second outlet channel.

Abstract: A drive unit for an injector includes an elastomeric drive member configured to possess a first elastic potential energy in an elastically stretched state that is releasable to convert the elastic energy to a first biasing force. A selectively releasable plunger rod has a locked position maintaining the elastomeric drive member in the elastically stretched state. A trigger member is biased by a second biasing force into an interlocking position. In the interlocking position, an arm of the trigger member interlocks with a notch of the plunger rod, thereby maintaining the plunger rod in the locked position thereof. The trigger member is selectively movable against the second biasing force to an unlocking position spaced from the notch, thereby releasing the first elastic potential energy into the first biasing force to axially advance the plunger rod and thus advance the piston through the reservoir.