Patents by Inventor James Gifford
James Gifford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11964008Abstract: The present disclosure relates to methods for inactivating a Zika virus which can be used in vaccines and immunogenic compositions. The present disclosure also relates to a method for determining the completeness of inactivation of an arbovirus preparation.Type: GrantFiled: September 13, 2022Date of Patent: April 23, 2024Assignee: Takeda Vaccines, Inc.Inventors: Jill A. Livengood, Holli Giebler, Hansi Dean, Tatsuki Satou, Raman Rao, Jackie Marks, Mark Lyons, Asae Shintani, James Gifford, Sushma Kommareddy
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Patent number: 11966340Abstract: To automate time series forecasting machine learning pipeline generation, a data allocation size of time series data may be determined based on one or more characteristics of a time series data set. The time series data may be allocated for use by candidate machine learning pipelines based on the data allocation size. Features for the time series data may be determined and cached by the candidate machine learning pipelines. Predictions of each of the candidate machine learning pipelines using at least the one or more features may be evaluated. A ranked list of machine learning pipelines may be automatically generated from the candidate machine learning pipelines for time series forecasting based upon evaluating predictions of each of the one or more candidate machine learning pipelines.Type: GrantFiled: March 15, 2022Date of Patent: April 23, 2024Assignee: International Business Machines CorporationInventors: Long Vu, Bei Chen, Xuan-Hong Dang, Peter Daniel Kirchner, Syed Yousaf Shah, Dhavalkumar C. Patel, Si Er Han, Ji Hui Yang, Jun Wang, Jing James Xu, Dakuo Wang, Gregory Bramble, Horst Cornelius Samulowitz, Saket K. Sathe, Wesley M. Gifford, Petros Zerfos
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Publication number: 20240122179Abstract: At least some aspects of this disclosure include one or more auxinic herbicides with relatively low volatility. Some of these compounds may be especially useful when used in the process of growing commercially important plants. Methods for using these actives to control the growth and spread of unwanted plants and/or to hasten the growth of desirable plants are also disclosed herein.Type: ApplicationFiled: February 4, 2022Publication date: April 18, 2024Applicant: CORTEVA AGRISCIENCE LLCInventors: DAVID SIMPSON, JEREMY KISTER, MEI LI, BIN WEI, JAMES GIFFORD
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Publication number: 20240024454Abstract: The present disclosure relates to methods for inactivating a Zika virus which can be used in vaccines and immunogenic compositions. The present disclosure also relates to a method for determining the completeness of inactivation of an arbovirus preparation and to a method for determining the residual formaldehyde content in a pharmaceutical composition comprising an inactivated virus.Type: ApplicationFiled: June 22, 2023Publication date: January 25, 2024Inventors: Jill A. LIVENGOOD, Holli Giebler, Hansi Dean, Tatsuki Satou, Raman Rao, Jackie Marks, Mark Lyons, Asae Shintani, James Gifford, Nao Ogasawara, Masafumi Misaki, Satoshi Adachi, Sushma Kommareddy
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Publication number: 20230398199Abstract: The present disclosure relates to Zika virus vaccines and immunogenic compositions having one or more antigens from a Zika virus (e.g., a Zika virus clonal isolate, a non-human cell adapted Zika virus, etc.Type: ApplicationFiled: November 30, 2018Publication date: December 14, 2023Inventors: Jill A. LIVENGOOD, Hansi DEAN, Htay Htay HAN, Raman RAO, Jackie MARKS, Gary DUBIN, Laurence DE MOERLOOZE, Hetal PATEL, Asae SHINTANI, Holli GIEBLER, James GIFFORD, Mark LYONS, Sushma KOMMAREDDY, Tatsuki SATOU
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Publication number: 20230204567Abstract: The present disclosure relates to a method for determining the potency of an antigen sample such as a vaccine antigen sample. The present disclosure is also related to a method for monitoring the potency of a vaccine antigen during the production process including purifying, inactivating and formulating the vaccine antigen and to a method for producing a virus vaccine. Further, the present disclosure relates to vaccines obtainable by the methods disclosed. In certain embodiments of the present invention the antigen sample is a zika virus antigen sample.Type: ApplicationFiled: March 19, 2021Publication date: June 29, 2023Applicant: Takeda Vaccines, Inc.Inventors: Jill LIVENGOOD, Michael JOHNSON, James GIFFORD, Tawnya NEAD, Mark LYONS, Jackie MARKS
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Publication number: 20230145065Abstract: The present disclosure relates to methods for inactivating a Zika virus which can be used in vaccines and immunogenic compositions. The present disclosure also relates to a method for determining the completeness of inactivation of an arbovirus preparation.Type: ApplicationFiled: September 13, 2022Publication date: May 11, 2023Applicant: TAKEDA VACCINES, INC.Inventors: Jill A. LIVENGOOD, Holli Giebler, Hansi Dean, Tatsuki Satou, Raman Rao, Jackie Marks, Mark Lyons, Asae Shintani, James Gifford, Sushma Kommareddy
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Publication number: 20220339144Abstract: Provided herein are compounds for the treatment or prevention of AMPK-(5? adenosine monophosphate-activated protein kinase) mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.Type: ApplicationFiled: April 6, 2022Publication date: October 27, 2022Inventors: Jinyue DING, Robert GOMEZ, James Gifford GUTHRIE, David Andrew POWELL, Tao SHENG
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Patent number: 11478541Abstract: The present disclosure relates to methods for inactivating a Zika virus which can be used in vaccines and immunogenic compositions. The present disclosure also relates to a method for determining the completeness of inactivation of an arbovirus preparation.Type: GrantFiled: November 5, 2018Date of Patent: October 25, 2022Assignee: Takeda Vaccines, Inc.Inventors: Jill A. Livengood, Holli Giebler, Hansi Dean, Tatsuki Satou, Raman Rao, Jackie Marks, Mark Lyons, Asae Shintani, James Gifford
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Publication number: 20210401422Abstract: A delicate tissue retraction system for use with a navigation probe having a probe shaft and a probe tip at a distal end of the probe shaft. The delicate tissue retraction system includes a retractor and an introducer that is removably installed within the retractor. The introducer has a wall forming a hollow channel extending from a proximal introducer end to a distal introducer end. A mount is integrally formed with the introducer and extends from the distal introducer end into the channel. The mount is positioned to surround the probe tip when the navigation probe is at a fully inserted position within the introducer with the probe tip at the distal introducer end.Type: ApplicationFiled: September 10, 2021Publication date: December 30, 2021Applicant: Vycor Medical, Inc.Inventors: Aaron James Gifford, Clark Berg Foster, Donald Clevenger
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Publication number: 20210403879Abstract: The present disclosure relates to methods for inactivating a Zika virus which can be used in vaccines and immunogenic compositions. The present disclosure also relates to a method for determining the completeness of inactivation of an arbovirus preparation and to a method for determining the residual formaldehyde content in a pharmaceutical composition comprising an inactivated virus.Type: ApplicationFiled: November 30, 2018Publication date: December 30, 2021Inventors: Jill A LIVENGOOD, Holli GIEBLER, Hansi DEAN, Tatsuki SATOU, Raman RAO, Jackie MARKS, Mark LYONS, Asae SHINTANI, James GIFFORD, Nao OGASAWARA, Masafumi MISAKI, Satoshi ADACHI
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Publication number: 20210378246Abstract: A herbicidal composition containing (a) a compound of formula (I): wherein X represents CH or N, hal represents F, Cl or Br, R is methyl or ethyl, and R? is H, methyl or ethyl, or an agriculturally acceptable salt or ester thereof, (b) a second herbicide comprising at least one organophosphorus herbicide, or an agriculturally acceptable salts, esters, and amides thereof; and/or (c) a third herbicide comprising at least one pyridine herbicide, or an agriculturally acceptable salts, esters, and amides thereof, provides control of undesirable vegetation e.g., in direct-seeded rice, water-seeded rice, transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, vegetables, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crops, vegetables, industrial vegetation management (IVM) and rights of way (ROW).Type: ApplicationFiled: October 31, 2019Publication date: December 9, 2021Applicant: DOW AGROSCIENCES LLCInventors: Andrea McVeigh-Nelson, Christopher John Voglewede, Richard Kevin Mann, Marcos Baez Buchanan, Rafael Frene, Luiz Henrique Zobiole, David Ouse, James Gifford
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Patent number: 11116487Abstract: A delicate tissue retraction system for use with a navigation probe having a probe shaft and a probe tip at a distal end of the probe shaft. The delicate tissue retraction system includes a retractor and an introducer that is removably installed within the retractor. The introducer has a wall forming a hollow channel extending from a proximal introducer end to a distal introducer end. A mount is integrally formed with the introducer and extends from the distal introducer end into the channel. The mount is positioned to surround the probe tip when the navigation probe is at a fully inserted position within the introducer with the probe tip at the distal introducer end.Type: GrantFiled: March 29, 2019Date of Patent: September 14, 2021Assignee: Vycor Medical, Inc.Inventors: Aaron James Gifford, Clark Berg Foster, Donald Clevenger
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Patent number: 10455837Abstract: Safener complexes comprising cloquintocet acid, or a salt thereof, and an amine-containing polymer or oligomer as well as compositions comprising these safener complexes are provided. Also provided are methods of controlling undesirable vegetation in a crop, comprising applying to vegetation or an area adjacent to the vegetation or applying to soil or water to prevent the emergence or growth of the undesirable vegetation in a crop, a safened herbicidal composition comprising a herbicide and a safener complex comprising cloquintocet acid, or a salt thereof, and an amine-containing polymer or oligomer.Type: GrantFiled: August 25, 2016Date of Patent: October 29, 2019Assignee: Dow ArgoSciences LLCInventors: Min Zhao, Lei Liu, David Ouse, James Gifford
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Publication number: 20190223853Abstract: A delicate tissue retraction system for use with a navigation probe having a probe shaft and a probe tip at a distal end of the probe shaft. The delicate tissue retraction system includes a retractor and an introducer that is removably installed within the retractor. The introducer has a wall forming a hollow channel extending from a proximal introducer end to a distal introducer end. A mount is integrally formed with the introducer and extends from the distal introducer end into the channel. The mount is positioned to surround the probe tip when the navigation probe is at a fully inserted position within the introducer with the probe tip at the distal introducer end.Type: ApplicationFiled: March 29, 2019Publication date: July 25, 2019Inventors: Aaron James Gifford, Clark Berg Foster, Donald Clevenger
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Patent number: 10327748Abstract: A delicate tissue retraction system having a retractor, an introducer and a clamp mechanism. The retractor has a hollow retractor passage and the introducer has an introducer channel extending from a proximal introducer end to a distal introducer end. The introducer is configured to be removably installed within the retractor. The clamp mechanism is on the introducer and includes a probe shaft receptacle suspended inwardly from the introducer wall to form one or more open spaces between the introducer wall and the probe shaft receptacle. The probe shaft receptacle has a clamp passage that is axially aligned with the introducer channel and dimensioned to receive the shaft of a navigation probe therethrough. The probe shaft receptacle has a clamp configured to selectively reduce a size of at least a first portion of the clamp passage to selectively hold the probe shaft at a fixed position relative to the introducer.Type: GrantFiled: June 5, 2017Date of Patent: June 25, 2019Assignee: Vycor Medical, Inc.Inventors: Aaron James Gifford, Clark Berg Foster, Donald Clevenger
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Publication number: 20170333017Abstract: A delicate tissue retraction system having a retractor, an introducer and a clamp mechanism. The retractor has a hollow retractor passage and the introducer has an introducer channel extending from a proximal introducer end to a distal introducer end. The introducer is configured to be removably installed within the retractor. The clamp mechanism is on the introducer and includes a probe shaft receptacle suspended inwardly from the introducer wall to form one or more open spaces between the introducer wall and the probe shaft receptacle. The probe shaft receptacle has a clamp passage that is axially aligned with the introducer channel and dimensioned to receive the shaft of a navigation probe therethrough. The probe shaft receptacle has a clamp configured to selectively reduce a size of at least a first portion of the clamp passage to selectively hold the probe shaft at a fixed position relative to the introducer.Type: ApplicationFiled: June 5, 2017Publication date: November 23, 2017Inventors: Aaron James Gifford, Clark Berg Foster, Donald Clevenger
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Patent number: 9737287Abstract: A delicate tissue retraction system having a retractor, an introducer and a clamp mechanism. The retractor has a hollow retractor passage extending along a longitudinal axis from a proximal retractor end to a distal retractor end. The introducer has an introducer channel extending from a proximal introducer end to a distal introducer end. The introducer is configured to be removably installed within the retractor such that the proximal introducer end and distal introducer end are located along the longitudinal axis and the distal introducer end extends beyond the distal retractor end. The clamp mechanism is located on the introducer and includes a clamp axially aligned with the introducer channel, and control member configured to move the clamp between an open position and a closed position. The clamp may be used to hold a navigation probe inside the introducer, and a registration indicator may confirm the proper installation of the probe.Type: GrantFiled: May 13, 2015Date of Patent: August 22, 2017Assignee: Vycor Medical, Inc.Inventors: Aaron James Gifford, Clark Berg Foster, Donald Clevenger
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Publication number: 20170202219Abstract: Disclosed herein is a herbicidal composition comprising a herbicidally effective amount of (a) pyroxsulam or an agriculturally acceptable salt thereof and (b) a cloquintocet salt. Also disclosed herein are methods of controlling undesirable vegetation with the compositions disclosed herein without excessive injury to desirable crops.Type: ApplicationFiled: January 12, 2017Publication date: July 20, 2017Inventors: David G. Ouse, Mei Li, James Gifford, Franklin Nelson Keeney, Hong Zhang
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Publication number: 20170151339Abstract: Particles, including nanoparticles and microparticles, and pharmaceutical formulations thereof, comprising conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety via a linker have been designed which can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or infectious diseases.Type: ApplicationFiled: June 30, 2015Publication date: June 1, 2017Inventors: Brian H. White, Rossitza G. Alargova, Patrick Rosaire Bazinet, Craig A. Dunbar, Patrick Lim Soo, Rajesh R. Shinde, Mark T. Bilodeau, Sudhakar Kadiyala, Richard Wooster, Timothy Barder, Kerry Whalen, James Gifford