Abstract: Multiple, separately administrated computer systems storing slices of the cipher text of a Personally Identifiable Information (PII) data item that is represented by a token. The token is used as a substitute of the data item. The data item is encrypted using a public key. To recover the data item, a complete set of the slices is retrieved from the separate computer systems and decrypted using the private key corresponding to the public key. Instances and circumstances of the usages of the data item can be recorded under the token in a blockchain ledger in connection with the retrieval and/or decryption of the cipher text. A data item owner may use the data item and the public key to recreate the cipher text, retrieve the token stored with the cipher text in the separate computer systems, and then query the ledger for a usage history of the data item.

Abstract: A package retention system and method to secure one or more packages to a fixture such as a door handle are provided. When packages are delivered while home owner is away, the delivered packages can be securely and safely retained using the package retention system. The package retention system includes a bag to accommodate packages, a pull string configured to wrap around an opening of the bag, and an enclosure that includes first and second locking mechanisms. The first locking mechanism locks or unlocks the pull string, and the second locking mechanism locks or unlocks a coupling member that is configured to be coupled to a fixture such as a door handle to secure the bag to the fixture.

Abstract: Multiple, separately administrated computer systems storing slices of the cipher text of a Personally Identifiable Information (PII) data item that is represented by a token. The token is used as a substitute of the data item. The data item is encrypted using a public key. To recover the data item, a complete set of the slices is retrieved from the separate computer systems and decrypted using the private key corresponding to the public key. Instances and circumstances of the usages of the data item can be recorded under the token in a blockchain ledger in connection with the retrieval and/or decryption of the cipher text. A data item owner may use the data item and the public key to recreate the cipher text, retrieve the token stored with the cipher text in the separate computer systems, and then query the ledger for a usage history of the data item.

Abstract: Multiple, separately administrated computer systems storing slices of the cipher text of a Personally Identifiable Information (PII) data item that is represented by a token. The token is used as a substitute of the data item. The data item is encrypted using a public key. To recover the data item, a complete set of the slices is retrieved from the separate computer systems and decrypted using the private key corresponding to the public key. Instances and circumstances of the usages of the data item can be recorded under the token in a blockchain ledger in connection with the retrieval and/or decryption of the cipher text. A data item owner may use the data item and the public key to recreate the cipher text, retrieve the token stored with the cipher text in the separate computer systems, and then query the ledger for a usage history of the data item.

Abstract: A package retention system and method to secure one or more packages to a fixture such as a door handle are provided. When packages are delivered while home owner is away, the delivered packages can be securely and safely retained using the package retention system. The package retention system includes a bag to accommodate packages, a pull string configured to wrap around an opening of the bag, and an enclosure that includes first and second locking mechanisms. The first locking mechanism locks or unlocks the pull string, and the second locking mechanism locks or unlocks a coupling member that is configured to be coupled to a fixture such as a door handle to secure the bag to the fixture.

Abstract: Multiple, separately administrated computer systems storing slices of the cipher text of a Personally Identifiable Information (PII) data item that is represented by a token. The token is used as a substitute of the data item. The data item is encrypted using a public key. To recover the data item, a complete set of the slices is retrieved from the separate computer systems and decrypted using the private key corresponding to the public key. Instances and circumstances of the usages of the data item can be recorded under the token in a blockchain ledger in connection with the retrieval and/or decryption of the cipher text. A data item owner may use the data item and the public key to recreate the cipher text, retrieve the token stored with the cipher text in the separate computer systems, and then query the ledger for a usage history of the data item.

Abstract: Systems and methods to store, exchange, and aggregate data in association tokens representative of personally identifiable information (PII) without revealing the PII to users of the data. The PII is secured in a centralized location for association with the tokens but without the associated data. Data records are stored in data sources in association with tokens representing the PII but without the PII. Before providing a set of data records from the data sources to a user, a master token is identified based on the data stored in the centralized location to represent a plurality of tokens used in the data records to represent a same person/entity; and the plurality of tokens are replaced with the master token for the data records to link together the data records of the same person/entity.

Abstract: A lighted workbag or backpack having a positionable light source configured so as to provide significant illumination into the interior portion of the workbag or an external work area or the path in front of the backpack. The light source having a gooseneck configuration is mounted in a column or pouch positioned in the back of the backpack that allows the light to extend over the shoulder of a user wearing the backpack so as to illuminate the area in front of the user.

Abstract: A lighted workbag or backpack having a positionable light source configured so as to provide significant illumination into the interior portion of the workbag or an external work area or the path in front of the backpack. The light source having a gooseneck configuration is mounted in a column or pouch positioned in the back of the backpack that allows the light to extend over the shoulder of a user wearing the backpack so as to illuminate the area in front of the user.

Abstract: The present invention is a bag holder/transport apparatus for plastic trash bags for use outdoors and indoors. A rim means is provided with a frame, a foot peg for pushing the end of the rim into the ground and an adjustable clamp assembly for attaching a trash bag positioned in the rim. An elongated strip of rigid material such as metal or plastic attached from the rim to the wheel base so as to support the trash bag is also provided so that the device can be used to wheel a filled bag to a disposal point after filling.

Abstract: A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Abstract: A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Abstract: A bone implant device comprising a plurality of interconnected plate members, at least one plate member defining a plurality of apertures therein adapted for permitting bone growth there through from an interior portion of the bone in which the device is implanted for aiding in securing the device within the interior portion, and wherein the device is configured and adapted to minimize contact with an interior surface of the bone. The device is useful in applications including, but not limited to, repairing bone fractures, modeling bone in growing subjects, service as artificial joints and anchoring prostheses, such as an artificial limb, to a bone stub in the body of a subject.

Abstract: C-terminal amidated human parathyroid hormone analogs PTH 1-32-NH2 and PTH 1-33-NH2 are biologically active and can be used for the treatment of various bone related diseases and conditions.

Abstract: Conversion in vitro of X-Gly to X-alpha-hydroxy-Gly or X—NH2 (X being a peptide or any other compound having a carbonyl group capable of forming a covalent bond with glycine) is accomplished enzymatically in the presence of keto acids, or salts or esters thereof, to provide a good yield without the necessity of catalase or similar enzymatic reaction enhancers. Peptidylglycine ?-amidating monooxygenase (PAM) is a preferred enzyme for catalyzing the conversion. Alternatively, peptidylglycine ?-hydroxylating monooxygenase (PHM) is utilized to convert X-Gly to X-alpha-hydroxy-Gly which may be recovered, or optionally may be simultaneously or sequentially converted to an amide by either a Lewis base or action of the enzyme peptidyl ?-hydroxyglycine ?-amidating lyase (PAL). Both PHM and PAL are functional domains of PAM.

Abstract: A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Abstract: Bioavailability of peptide active agents to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine by combining the composition with an absorption enhancer. Bioavailability is further significantly increased by administering the composition in an acid-resistant protective vehicle which transports components of the invention through the stomach. The composition may optionally further include a sufficient amount of a pH-lowering agent to lower local intestinal pH. All components are released together into the intestine with the peptide.

Abstract: A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Abstract: C-terminal amidated human parathyroid hormone analogs PTH 1-32-NH2 and PTH 1-33-NH2 are biologically active and can be used for the treatment of various bone related diseases and conditions.

Abstract: A kit for changing a tire having a portable carrying case with a first compartment and a second compartment which are movable between an open position and a closed position. The first compartment is used for housing an air compressor motor and a tank for holding compressed air and the second compartment includes a plurality of preformed depressions for containing an impact wrench, a tire jack and a plurality of hoses therein. The compressed air holding tank includes a plurality of air connector ports for attaching the hoses to the air connector ports and to the impact wrench and to the tire jack.