Patents by Inventor James GIULIANOTTI

James GIULIANOTTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF PRODUCING TWO CHAIN PROTEINS IN BACTERIA
    Publication number: 20220162286
    Abstract: Provided herein are methods of producing a recombinant polypeptide containing two chains, such as an immune mobilizing monoclonal T-cell receptor against cancer (ImmTAC) protein including an alpha chain and a beta chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Application
    Filed: July 6, 2021
    Publication date: May 26, 2022
    Applicant: Genentech, Inc.
    Inventors: James GIULIANOTTI, Dorothea E. REILLY, Kieran AURORI, Laura C. SIMMONS
  • Methods of producing two chain proteins in bacteria
    Patent number: 11299539
    Abstract: Provided herein are methods of producing a polypeptide containing two chains, such as an antibody including a light chain and a heavy chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: April 12, 2022
    Assignee: Genentech, Inc.
    Inventors: James Giulianotti, Dorothea E. Reilly
  • Methods of producing two chain proteins in bacteria
    Patent number: 11091530
    Abstract: Provided herein are methods of producing a recombinant polypeptide containing two chains, such as an immune mobilizing monoclonal T-cell receptor against cancer (ImmTAC) protein including an alpha chain and a beta chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: August 17, 2021
    Assignee: Genentech, Inc.
    Inventors: James Giulianotti, Dorothea E. Reilly, Kieran Aurori, Laura C. Simmons
  • METHODS OF PRODUCING TWO CHAIN PROTEINS IN BACTERIA
    Publication number: 20190112368
    Abstract: Provided herein are methods of producing a polypeptide containing two chains, such as an antibody including a light chain and a heavy chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Application
    Filed: September 21, 2018
    Publication date: April 18, 2019
    Applicant: Genentech, Inc.
    Inventors: James GIULIANOTTI, Dorothea E. REILLY
  • METHODS OF PRODUCING TWO CHAIN PROTEINS IN BACTERIA
    Publication number: 20190085045
    Abstract: Provided herein are methods of producing a recombinant polypeptide containing two chains, such as an immune mobilizing monoclonal T-cell receptor against cancer (ImmTAC) protein including an alpha chain and a beta chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Application
    Filed: July 25, 2018
    Publication date: March 21, 2019
    Applicant: Genentech, Inc.
    Inventors: James GIULIANOTTI, Dorothea E. REILLY, Kieran AURORI, Laura C. SIMMONS
  • Methods of producing two chain proteins in bacteria
    Patent number: 10112994
    Abstract: Provided herein are methods of producing a polypeptide containing two chains, such as an antibody including a light chain and a heavy chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: October 30, 2018
    Assignee: GENENTECH, INC.
    Inventors: James Giulianotti, Dorothea Reilly
  • Methods of producing two chain proteins in bacteria
    Patent number: 10066002
    Abstract: Provided herein are methods of producing a recombinant polypeptide containing two chains, such as an immune mobilizing monoclonal T-cell receptor against cancer (ImmTAC) protein including an alpha chain and a beta chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: September 4, 2018
    Assignee: GENENTECH, INC.
    Inventors: James Giulianotti, Dorothea Reilly, Kieran Aurori, Laura C. Simmons
  • METHODS OF PRODUCING TWO CHAIN PROTEINS IN BACTERIA
    Publication number: 20160159898
    Abstract: Provided herein are methods of producing a polypeptide containing two chains, such as an antibody including a light chain and a heavy chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Application
    Filed: November 5, 2015
    Publication date: June 9, 2016
    Applicant: GENENTECH, INC.
    Inventors: James GIULIANOTTI, Dorothea REILLY
  • METHODS OF PRODUCING TWO CHAIN PROTEINS IN BACTERIA
    Publication number: 20160159880
    Abstract: Provided herein are methods of producing a recombinant polypeptide containing two chains, such as an immune mobilizing monoclonal T-cell receptor against cancer (ImmTAC) protein including an alpha chain and a beta chain. In particular, methods are provided for producing heterologous secretory proteins in bacteria through utilization of optimized expression vectors and culture processes.
    Type: Application
    Filed: November 5, 2015
    Publication date: June 9, 2016
    Applicant: GENENTECH, INC.
    Inventors: James GIULIANOTTI, Dorothea REILLY, Kieran Aurori, Laura C. Simmons