Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that modulate (e.g., agonizes or partially agonizes) NLRP3 that are useful, e.g., for treating a condition, disease or disorder in which an increase in NLRP3 signaling may correct a deficiency in innate immune activity (e.g., a condition, disease or disorder associated with an insufficient immune response) that contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.

Abstract: A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment.

Abstract: A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment.

Abstract: A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment.

Abstract: A multiple access wireless communications architecture provides selective, simultaneous communications with wireless devices located in different sections of a spatial area around a communications apparatus referred to as “sectors”. In one embodiment, channel allocation techniques for increasing one or more of throughput and coverage in a wireless communications environment.

Abstract: A remotely controllable computing and multimedia entertainment system includes a personal computer (24) having an entertainment circuit (12) made up of a radio frequency circuit (48), a television circuit (46), and an audio multimedia circuit (18). A remote control circuit (50) provides programmable control of the entertainment circuit (12) to select among computer function operation, television and radio operation, and audio operation. An analog mixing circuit (70) within the audio multimedia circuit (18) provides mixing for a plurality of analog audio signals. A telephone circuit (44) integrates data, fax, and voice telephone signals in the entertainment circuit (12). A volume control circuit (318) within the audio multimedia circuit (18) provides varying volume, bass, and tone levels for each audio signal received by the analog mixing circuit (70). The analog audio signals received by analog mixing circuit (70) may include monaural and stereo audio signals.

Abstract: A multipurpose computerized television system generates a plurality of video images in association with a personal computer. A television circuit associates with the personal computer and is within the personal computer chassis for receiving a plurality of television signals and directing the signals to the monitor for the monitor to display. An audio multimedia circuit associates with the personal computer and the television circuit and is also located within the chassis for receiving and processing audio data from the television circuit. The audio multimedia circuit also communicates the audio multimedia data to the personal computer. Control circuitry associated with the television circuit and the personal computer within the chassis controls the operation of the television circuit through the personal computer. The control circuitry comprises a remote control circuit for remotely and independently controlling the television circuit and the personal computer.