Abstract: The present invention provides compounds of Formula XA-1, XA-2, XA-3, XA-4, XA-5, or XA-6, or metabolites of Compound 1 or metabolites of a compound of Formula I, PA-I, or PA-III, including compositions and salts thereof, which are useful in the prevention and/or treatment of a disease or disorder such as T2DM, obesity, or NASH, as well as analytical methods related to the administration of Compound 1 or a compound of Formula I, PA-1, or PA-III.

Abstract: A joint distraction device that is wearable by a patient and user-friendly and associated methods of joint distraction. Such devices can include first and second anchors that secure portions of the patient's body proximal and distal of the joint, the anchors each being attached to a beam and a distance between first and second anchors being adjustable so as to hold the joint being investigated in distraction. For distraction of a wrist joint, the first anchor can be a finger clamp and the second anchor can be an arm sleeve. The finger clamp can include multiple finger traps. The distance between anchors can be adjusted by an adjuster, by extending the beam or by moving an anchor incrementally along the beam. Advantageously, the device is fully wearable by the patient without being attached to external components, thereby improving patient comfort, portability and ease of use.

Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.

Abstract: In a first aspect, a system for creating fact-based content is presented. The system includes an application service provider operating on a network. The application service provider is configured to receive a user prompt and generate a web query for content based on the user prompt. The system includes a fact-based language model in communication with the application service provider. The fact-based language model is configured to receive the web query from the application service provider and retrieve, from a electronic library, relevant fact-based content based on the web query. The electronic library includes proprietary data. The fact-based language model is configured to provide the relevant fact-based content to the application service provider. The application service provider communicates content to a user based on the user prompt. The content includes at least a portion of the relevant fact-based content from the electronic library.

Abstract: A system for reactivating a catalyst having a predetermined heat content includes a reactor, a regenerator, and an electrically energized heater. The reactor is configured to generate a spent catalyst. The regenerator is configured to receive the spent catalyst from the reactor. The electrically energized heater has a plurality of energy emitting members at least partially immersed in the spent catalyst. The heater is configured to provide a supplemental heat content to obtain the predetermined heat content.

Abstract: A system for processing a selected feedstock using a catalyst includes a reactor, a catalyst recovery system, and a conduit. The reactor receives the catalyst and the selected feedstock. A reaction between the selected feedstock and the catalyst generates a spent catalyst. The catalyst recovery system processes the spent catalyst. The conduit connects the reactor to the catalyst recovery system and has a lateral section. The spent catalyst flows from the reactor through a flow space defined by an inner wall of the lateral section to the catalyst recovery system. The system also includes a fluidizer positioned at the lateral section. The fluidizer includes at least one nozzle. The at least one nozzle is completely inside the flow space. The at least one nozzle forms and directs a jet of a fluidizing agent into the spent catalyst in the lateral section.

Abstract: A system for processing a selected feedstock using a catalyst includes a reactor, a catalyst recovery system, and a conduit. The reactor receives the catalyst and the selected feedstock. A reaction between the selected feedstock and the catalyst generates a spent catalyst. The catalyst recovery system processes the spent catalyst. The conduit connects the reactor to the catalyst recovery system and has a lateral section. The spent catalyst flows from the reactor through a flow space defined by an inner wall of the lateral section to the catalyst recovery system. The system also includes a fluidizer positioned at the lateral section. The fluidizer includes at least one nozzle. The at least one nozzle is completely inside the flow space. The at least one nozzle forms and directs a jet of a fluidizing agent into the spent catalyst in the lateral section.

Abstract: An optical cable includes a main body and a termination segment extending from an end of the main body. The main body includes middle portions of optical fibers. The termination segment includes end portions of the optical fibers and multi-fiber connectors attached to the end portions of the optical fibers. The multi-fiber connectors are staggered along a length of the termination segment.

Abstract: An optical cable includes a main body and a termination segment extending from an end of the main body. The main body includes middle portions of optical fibers. The termination segment includes end portions of the optical fibers and multi-fiber connectors attached to the end portions of the optical fibers. The multi-fiber connectors are staggered along a length of the termination segment.

Abstract: A reactor system and method for catalytic dehydrogenation of saturated C3-C6 hydrocarbons within a reactor placed within a reactor disengager, where the reactor is open at the bottom thereof and open to the disengager, and the exit riser from the reactor is not hard coupled to at least one downstream cyclone. This configuration permits controlling the amount of catalyst within the reactor by varying the level of catalyst in the reactor disengager outside the reactor and permits controlling total catalyst hold-up and/or weight hourly space velocity (WHSV) independently from catalyst flow from the catalyst regenerator.

Abstract: The invention relates to an optical fiber connector and to a related method for changing the polarity thereof. The connector comprises a ferrule, housing a plurality of terminations of optical fibers, and an inner housing arranged around the ferrule and comprising a rear portion and a front portion configured to be inserted into an optical fiber adapter.

Abstract: An optical fibre unit includes one or more optical fibres; an outer jacket surrounding the one or more optical fibres, made of a fibre reinforced polymer comprising inorganic fibres embedded in a polymer matrix in an amount comprised between 5 and 25 wt % with respect to the weight of the fibre reinforced polymer, the inorganic fibres having a median length (d50) comprised between 50 and 250 ?m; and a skin layer surrounding the outer jacket and in direct contact thereto, having a thickness comprised between 0.05 mm and 0.5 mm and being free from fibres.

Abstract: The present disclosure relates to a system, method, and computer program for extracting utterances corresponding to a user problem statement in a conversation between a human agent and a user. The system obtains a set of utterances from a natural language conversation between the human agent and the user. The system uses a problem-statement classifier to obtain machine-generated predictions as to whether each natural language utterance in the set relates to a problem statement. The system selects one or more utterances from the set as corresponding to a problem statement based on the predictions. The system provides the selected utterances to a downstream system for further processing. In certain embodiments, the problem statement classifier includes an encoder that creates an utterance embedding for each utterance and a prediction module that uses the utterance embeddings to predict whether each utterance corresponds to a user problem statement.

Abstract: The invention relates to an optical fiber connector and to a related method for changing the polarity thereof. The connector comprises a ferrule, housing a plurality of terminations of optical fibers, and an inner housing arranged around the ferrule and comprising a rear portion and a front portion configured to be inserted into an optical fiber adapter.

Abstract: An optical cable includes a main body and a termination segment extending from an end of the main body. The main body includes middle portions of optical fibers. The termination segment includes end portions of the optical fibers and multi-fiber connectors attached to the end portions of the optical fibers. The multi-fiber connectors are staggered along a length of the termination segment.

Abstract: There is provided a method for manufacturing graphene, the method comprising: forming graphene on a non-metallic surface of a substrate by CVD in a CVD reaction chamber, wherein the step of forming graphene comprises introducing a precursor in a gas phase and/or suspended in a gas into the CVD reaction chamber; wherein the precursor consists of one or more compounds selected from a C4—C10 organic compound; wherein the organic compound is branched such that the organic compound has at least three methyl groups; and wherein the organic compound consists of carbon and hydrogen and, optionally, oxygen, fluorine, chlorine and/or bromine.

Abstract: Segmentation of bony regions in MRI images of joints is automated using a two-stage process. In a first stage, a machine-learning image-slice categorizer is used to categorize image slices of the MRI image data as belonging to one of a set of image-slice categories, depending on presence or absence of bone and/or tendon in the image slice. In a second stage, a first instance of a machine-learning segmentation classifier is used to segment image slices that contain both bone and tendon into bone and non-bone regions, and a second instance of a machine-learning segmentation classifier is used to segment image slices that contain bone but not tendon into bone regions and non-bone regions. Results from the two segmentation classifiers can be combined across image slices to provide a final segmentation of the bony structures, including inflammatory regions, in the image data.

Abstract: A cable contains a core including a transmissive element and a coating layer made of a coating material. The coating material contains, with respect to the total weight of polymeric materials present in the composition, (i) 70% to 95% by weight of a recycled linear low density polyethylene (r-LLDPE); and (ii) 5 to 30% by weight of an ethylene-vinyl acetate copolymer (EVA). The coating layer shows mechanical properties comparable to those of a virgin polymer composition and better, both before and after ageing, than recycled polymer-based compositions containing recycled LLDPE but free from EVA. The EVA may be added to the r-LLDPE or, alternatively, be already contained in the r-LLDPE as a result of previous LLDPE use. The cable may further contain a skin layer placed around and in direct contact with the coating layer based on r-LLDPE.

Abstract: An optical fibre unit includes one or more optical fibres; an outer jacket surrounding the one or more optical fibres, made of a fibre reinforced polymer comprising inorganic fibres embedded in a polymer matrix in an amount comprised between 5 and 25 wt % with respect to the weight of the fibre reinforced polymer, the inorganic fibres having a median length (d50) comprised between 50 and 250 ?m; and a skin layer surrounding the outer jacket and in direct contact thereto, having a thickness comprised between 0.05 mm and 0.5 mm and being free from fibres.

Abstract: The invention relates to an optical fiber connector and to a related method for changing the polarity thereof. The connector comprises a ferrule, housing a plurality of terminations of optical fibers, and an inner housing arranged around the ferrule and comprising a rear portion and a front portion configured to be inserted into an optical fiber adapter.