Patents by Inventor James H. Ackerman

James H. Ackerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Saccharin derivative proteolytic enzyme inhibitors
    Patent number: 5466701
    Abstract: Compounds having the structural formula ##STR1## which inhibit the enzymatic activity of proteolytic enzymes, and processes for preparation thereof, method of use thereof in treatment of degenerative diseases and pharmaceutical compositions thereof are disclosed.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: November 14, 1995
    Assignee: Sterling Winthrop Inc.
    Inventors: Dennis J. Hlasta, James H. Ackerman, Albert J. Mura, Ranjit C. Desai
  • Saccharin derivative proteolytic enzyme inhibitors
    Patent number: 5378720
    Abstract: Compounds having the structural formula ##STR1## which inhibit the enzymatic activity of proteolytic enzymes, and processes for preparation thereof, method of use thereof in treatment of degenerative diseases and pharmaceutical compositions thereof are disclosed.
    Type: Grant
    Filed: May 25, 1993
    Date of Patent: January 3, 1995
    Assignee: Sterling Winthrop Inc.
    Inventors: Dennis J. Hlasta, James H. Ackerman, Albert J. Mura, Ranjit C. Desai
  • Pyrazolo[3,4-b]quinolines and their use as antiviral agents
    Patent number: 4920128
    Abstract: Pyrazolo[3,4-b]quinolines having the formula ##STR1## where R is hydrogen, hydroxy or alkoxy; R.sub.2 is halogen, cyano, carbamyl, carboxy, lower-alkylcarbonyl, amino or aminomethyl; and R.sub.1 is hydrogen or selected substituents as defined herein, are useful as antiviral agents and/or as vasodilators.
    Type: Grant
    Filed: May 20, 1988
    Date of Patent: April 24, 1990
    Assignee: Sterling Drug Inc.
    Inventors: Malcolm R. Bell, James H. Ackerman
  • Iodinated anilic acids
    Patent number: 4111937
    Abstract: 3-Amino-2,4,6-triiodobenzoic acids optionally substituted in the 5-position by amino or carboxy or a derivative thereof react with dibasic acid anhydrides to give the corresponding cyclic imides (A), which can be hydrolyzed to the corresponding anilic acids (B). The latter can be further alkylated on the anilide nitrogen atom. Compounds A and B are useful as cholecystographic and urographic agents.
    Type: Grant
    Filed: October 18, 1976
    Date of Patent: September 5, 1978
    Assignee: Sterling Drug Inc.
    Inventor: James H. Ackerman
  • Iodinated anilic acids
    Patent number: 4031088
    Abstract: 3-Amino-2,4,6-triiodobenzoic acids optionally substituted in the 5-position by amino or carboxy or a derivative thereof react with dibasic acid anhydrides to give the corresponding cyclic imides (A), which can be hydrolyzed to the corresponding anilic acids (B). The latter can be further alkylated on the anilide nitrogen atom. Compounds A and B are useful as cholecystographic and urographic agents.
    Type: Grant
    Filed: June 10, 1974
    Date of Patent: June 21, 1977
    Assignee: Sterling Drug Inc.
    Inventor: James H. Ackerman
  • Composition and method for treatment of hyperuricemia
    Patent number: 3931409
    Abstract: Trichloroamino(and acylamino)phenylalkanoic acids or esters, useful as uricosuric agents, are prepared by chlorination of the corresponding aminophenylalkanoic acids or esters, followed, if desired, by N-acylation and N-alkylation.
    Type: Grant
    Filed: November 4, 1974
    Date of Patent: January 6, 1976
    Assignee: Sterling Drug Inc.
    Inventors: Ardie R. Nickel, Franklin J. Rosenberg, James H. Ackerman