Abstract: Disclosed herein are methods and compositions for prognosing or diagnosing an obstructive renal dysfunction or ureteropelvic junction obstruction (UPJO) in a subject, involving detecting in a urine sample from a subject one or more proteins selected from the group consisting of Immunoglobulin superfamily containing leucine-rich repeat protein (ISLR); Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT); Prostaglandin reductase 1 (PTGR1); Vascular cell adhesion protein 1 (VCAM1); and Ficolin-2 (FCN2), or detectable portions thereof to identify the subject as at risk of or having an obstructive renal dysfunction or UPJO.

Abstract: A self-heading stud and screw rivet fastener with an elongated shank having a socket at one end, a threaded portion adjacent the socket end, an enlarged head secured to or formed on its other end, and a central reduced diameter portion. A tubular sleeve and a washer providing a radial flange at one end of the sleeve are positioned around the reduced diameter portion of the shank. Preferably, the washer and sleeve are a one-piece annulus. The diameter of the sleeve through bore is less than either the enlarged head or the threaded portion of the shank so that the annulus is centrally entrapped on the shank. By inserting the fastener into a hole in a workpiece, using the socket to hold the shank from rotation, and tightening a nut engaging the threaded portion of the shank, the enlarged head is drawn toward and into the annulus to deform it and secure the fastener to the workpiece.