Patents by Inventor James H. Werner

James H. Werner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-dimensional imaging at nanometer resolutions
    Patent number: 7675045
    Abstract: An apparatus and method for enabling precise, 3-dimensional, photoactivation localization microscopy (PALM) using selective, two-photon activation of fluorophores in a single z-slice of a sample in cooperation with time-gated imaging for reducing the background radiation from other image planes to levels suitable for single-molecule detection and spatial location, are described.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: March 9, 2010
    Assignee: Los Alamos National Security, LLC
    Inventors: James H. Werner, Peter M. Goodwin, Andrew P. Shreve
  • Apparatus and method for tracking a molecule or particle in three dimensions
    Patent number: 7498551
    Abstract: An apparatus and method were used to track the movement of fluorescent particles in three dimensions. Control software was used with the apparatus to implement a tracking algorithm for tracking the motion of the individual particles in glycerol/water mixtures. Monte Carlo simulations suggest that the tracking algorithms in combination with the apparatus may be used for tracking the motion of single fluorescent or fluorescently labeled biomolecules in three dimensions.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: March 3, 2009
    Assignee: Los Alamos National Security, LLC
    Inventors: James H. Werner, Peter M. Goodwin, Guillaume Lessard
  • Apparatus and method for tracking a molecule or particle in three dimensions
    Publication number: 20080085550
    Abstract: An apparatus and method were used to track the movement of fluorescent particles in three dimensions. Control software was used with the apparatus to implement a tracking algorithm for tracking the motion of the individual particles in glycerol/water mixtures. Monte Carlo simulations suggest that the tracking algorithms in combination with the apparatus may be used for tracking the motion of single fluorescent or fluorescently labeled biomolecules in three dimensions.
    Type: Application
    Filed: October 6, 2006
    Publication date: April 10, 2008
    Inventors: James H. Werner, Peter M. Goodwin, Guillaume Lessard