Abstract: A method of enhancing sperm fertility is described herein. The method includes contacting sperm with hydroxyurea. A composition is disclosed that includes sperm, hydroxyurea, and a buffer. Methods, kits, and compositions for enhancing sperm fertility are also provided.

Abstract: A method of enhancing sperm fertility is described herein. The method includes contacting sperm with hydroxyurea. A composition is disclosed that includes sperm, hydroxyurea, and a buffer. Methods, kits, and compositions for enhancing sperm fertility are also provided.

Abstract: An improvement in a process for the production of ethylbenzene from a dilute ethylene stream wherein an ethylene-containing stream derived from a cracking process is directed to an ethylene fractionator for separation of ethylene and ethane. The improvement includes providing the dilute ethylene stream by liquefying and separating out a portion of the ethylene-containing stream prior to directing the remainder of the ethylene-containing stream to the ethylene fractionator and/or by drawing off a side stream from the ethylene fractionator; and, directing the dilute ethylene stream as a feed to an alkylator for alkylation with benzene to produce ethylbenzene.

Abstract: This invention relates to cholesterol-sequestering agents and methods of using cholesterol-sequestering agents to prevent infection. The compositions of the invention can be used to reduce or prevent maternal to fetal transmission of a microorganism and/or to reduce or eliminate a microorganism present in a blood sample or a blood product.

Abstract: Methods of reducing the risk of transmission of a sexually transmitted pathogen by contacting the pathogen or cells susceptible to infection by the pathogen with a ?-cyclodextrin are provided. Methods for reducing the risk of transmission of a sexually transmitted pathogen to or from a subject by contacting the pathogen or cells susceptible to the pathogen in the subject with a pharmaceutical composition containing a ?-cyclodextrin also are provided. Accordingly, pharmaceutical compositions, which include 1) a ?-cyclodextrin, which is in an amount that blocks passage of the pathogen through lipid rafts in the membrane of a cell susceptible to the pathogen, and 2) a contraceptive, an agent for treating a sexually transmitted disease, a lubricant, or a combination thereof, are provided, as are composition formulated from a solid substrate that contains an amount of ?-cyclodextrin useful for reducing the risk of transmission of a sexually transmitted pathogen.

Abstract: The invention provides enantiomers of ajoene and derivatives of Z(?)-ajoene. The derivative of Z(?)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.

Abstract: The present invention relates to sigma-2 receptor agonists and their use in the treatment of immunodeficiency virus infections, especially human immunodeficiency virus (HIV) infections. The invention particularly relates to sigma-2 agonists, especially CB-184 and its analogues, that decrease cellular production of sphingomyelin when provided to recipient cells, and inhibit HIV replication.

Abstract: Methods of reducing the risk of transmission of a sexually transmitted pathogen by contacting the pathogen or cells susceptible to infection by the pathogen with a ?-cyclodextrin are provided. Methods for reducing the risk of transmission of a sexually transmitted pathogen to or from a subject by contacting the pathogen or cells susceptible to the pathogen in the subject with a pharmaceutical composition containing a ?-cyclodextrin also are provided. Accordingly, pharmaceutical compositions, which include 1) a ?-cyclodextrin, which is in an amount that blocks passage of the pathogen through lipid rafts in the membrane of a cell susceptible to the pathogen, and 2) a contraceptive, an agent for treating a sexually transmitted disease, a lubricant, or a combination thereof, are provided, as are composition formulated from a solid substrate that contains an amount of ?-cyclodextrin useful for reducing the risk of transmission of a sexually transmitted pathogen.

Abstract: Monoclonal antibodies and method for ameliorating an immune response disorder. The monoclonal antibodies are specific for an epitope present on the leukocyte adhesion receptor ?-chain.

Abstract: An improvement in a process for the production of ethylbenzene from a dilute ethylene stream wherein an ethylene-containing stream derived from a cracking process is directed to an ethylene fractionator for separation of ethylene and ethane. The improvement includes providing the dilute ethylene stream by liquefying and separating out a portion of the ethylene-containing stream prior to directing the remainder of the ethylene-containing stream to the ethylene fractionator and/or by drawing off a side stream from the ethylene fractionator; and, directing the dilute ethylene stream as a feed to an alkylator for alkylation with benzene to produce ethylbenzene.

Abstract: This invention relates to cholesterol-sequestering agents and methods of using cholesterol-sequestering agents to prevent infection. The compositions of the invention can be used to decontaminate skin and environmental surfaces that are contacted with microorganisms such as envelope viruses.