Abstract: The present disclosure provides a process for the preparation of developer compositions comprising: a first developer comprised of carrier and toner comprised of resin, pigment, polyolefin, compatibilizer, charge control agent, and metal oxide surface additive, and adding thereto a second developer comprised of carrier, and second compatibilizer, charge control agent, and metal oxide surface additive. The second developer can be directly dispensed into a developer housing.

Abstract: An adapter for connecting a vacuum source to an intraoral device has a plug portion and a connection portion extending proximally from the plug portion. The plug portion is configured for releasable mating engagement with a connection section of an intraoral device which communicates with one or more evacuation channels of the intraoral device. The connection portion has a proximal end configured for connection to one or more vacuum lines of a vacuum source. One or more vacuum lumens extend through the plug and connector portions to communicate with the one or more vacuum lines to remove fluid from a patient's mouth.

Abstract: The present disclosure provides a process for the preparation of developer compositions comprising: a first developer comprised of carrier and toner comprised of resin, pigment, polyolefin, compatibilizer, charge control agent, and metal oxide surface additive, and adding thereto a second developer comprised of carrier, and second compatibilizer, charge control agent, and metal oxide surface additive. The second developer can be directly dispensed into a developer housing.

Abstract: An air water vacuum dental instrument includes a handle; a head; an air control carried by at least one of the handle and the head; a water control carried by at least one of the handle and the head; a vacuum control carried by at least one of the handle and the head; and an air water vacuum tip coupled to the head and configured to provide at least air, water, and vacuum in a mouth of a dental patient at the air water vacuum tip.

Abstract: An air water vacuum dental instrument includes a handle; a head; an air control carried by at least one of the handle and the head; a water control carried by at least one of the handle and the head; a vacuum control carried by at least one of the handle and the head; and an air water vacuum tip coupled to the head and configured to provide at least air, water, and vacuum in a mouth of a dental patient at the air water vacuum tip.

Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.

Abstract: The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a ?-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a ?-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a ?-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a ?-lactmase or instructions for using the components in an assay.

Abstract: An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

Abstract: An air water vacuum dental instrument includes a handle; a head; an air control carried by at least one of the handle and the head; a water control carried by at least one of the handle and the head; a vacuum control carried by at least one of the handle and the head; and an air water vacuum tip coupled to the head and configured to provide at least air, water, and vacuum in a mouth of a dental patient at the air water vacuum tip.

Abstract: An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

Abstract: An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

Abstract: An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

Abstract: An adapter for connecting a vacuum source to an intraoral device has a plug portion and a connection portion extending proximally from the plug portion. The plug portion is configured for releasable mating engagement with a connection section of an intraoral device which communicates with one or more evacuation channels of the intraoral device. The connection portion has a proximal end configured for connection to one or more vacuum lines of a vacuum source. One or more vacuum lumens extend through the plug and connector portions to communicate with the one or more vacuum lines to remove fluid from a patient's mouth.

Abstract: An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

Abstract: An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

Abstract: An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

Abstract: A method of using a heat sink device with an intraoral illumination device includes inserting an intraoral illumination device at least partially in a patient's mouth, connecting a heat sink device to the intraoral illumination device, the heat sink device including an illumination device that emits light and heat when activated and a heat sink member thermally coupled to the illumination device; activating the illumination device so that light is transmitted to the intraoral illumination device and into the patient's mouth, aspirating fluid from the patient's mouth at negative pressure; and causing aspirated fluid to flow past the heat sink member at negative pressure so that heat is removed from the heat sink member, causing the illumination device to be cooled.