Abstract: The present invention relates to solid compositions of pharmaceutically active compounds, aqueous dispersions derived from these compositions and processes for the preparation of these solid compositions and dispersions. The present invention also relates to pharmaceutical compositions derived from these solid compositions and dispersions, and their use in the treatment and/or prophylaxis of helminthic, protozoal, and viral infections.

Abstract: A computer system with a first messaging application communicates a message to another computer system with a second messaging application via a coupling facility storage device. If the message does not exceed a predetermined threshold, the message is put onto the queue in the coupling facility. If the message does exceed a predetermined threshold, the message is put onto a log associated with the first messaging application and readable by the second messaging application. A pointer to the message is put onto the queue in the coupling facility. The pointer can be used to access the message in the log.

Abstract: The present invention provides a composition comprising nanoparticles of prodrugs of certain pharmaceutically active agents, wherein the nanoparticles of prodrugs are dispersed within a carrier material. The present invention further provides processes for the making of the same.

Abstract: Method and system are provided for running a smaller memory-address width program in a larger memory-address width address space. The method includes: dividing a smaller memory-address width program executable code into a set of portions; reserving a first virtual storage area in a part of an address space accessed using a smaller memory-address width address; and reserving a set of second virtual storage areas in a part of the address space accessed using a larger memory-address width address to accommodate the program executable code. The method provides a relocation mechanism to relocate a processor thread by translating using a relocation factor from an address in the reserved first virtual storage area to the one of the reserved second virtual storage areas containing the executable code.

Abstract: A computer system with a first messaging application communicates a message to another computer system with a second messaging application via a coupling facility storage device. If the message does not exceed a predetermined threshold, the message is put onto the queue in the coupling facility. If the message does exceed a predetermined threshold, the message is put onto a log associated with the first messaging application and readable by the second messaging application. A pointer to the message is put onto the queue in the coupling facility. The pointer can be used to access the message in the log.

Abstract: A first aspect of the present invention provides a method of producing a liquid composition comprising stabilised particles of active species in oil by precipitating a solution of the active species in a non-solvent in the presence of one or more stabilisers, mixing the precipitate suspension with an oil and then removing the solvents. Further aspects of the present invention relate to liquid compositions produced by said method and methods of use of such liquid compositions.

Abstract: A computer system with a first messaging application communicates a message to another computer system with a second messaging application via a coupling facility storage device. If the message does not exceed a predetermined threshold, the message is put onto the queue in the coupling facility. If the message does exceed a predetermined threshold, the message is put onto a log associated with the first messaging application and readable by the second messaging application. A pointer to the message is put onto the queue in the coupling facility. The pointer can be used to access the message in the log.

Abstract: The present invention provides a composition comprising nanoparticles of prodrugs of certain pharmaceutically active agents, wherein the nanoparticles of prodrugs are dispersed within a carrier material. The present invention further provides processes for the making of the same.

Abstract: An oil-in-water emulsion comprises an emulsifier which is a non-gelled branched polymer (e.g. a branched vinyl polymer), wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm. This is useful in, for example, facilitating the carrying of hydrophobic materials within aqueous systems, to enhance oral drug delivery. The oil-in-water emulsion may be prepared by mixing an oil phase with an aqueous phase in the presence of an emulsifier, wherein said emulsifier is a non-gelled branched polymer, wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm.

Abstract: The present invention is an alignment device for a bag containing one or more ports. The alignment device is attached to either the one or more ports or to the bag adjacent the one or more ports. The plate has an indicator or a unique outer edge shape that is designed to fit into a corresponding unique opening in a holder to ensure proper alignment of the bag and its port(s) in the holder. The plate is has a series of holes equal to and in alignment with the one or more ports of the bag and the port(s) extend through the holes of the plate.

Abstract: An oil-in-water emulsion comprises an emulsifier which is a non-gelled branched polymer (e.g. a branched vinyl polymer), wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm. This is useful in, for example, facilitating the carrying of hydrophobic materials within aqueous systems, to enhance oral drug delivery. The oil-in-water emulsion may be prepared by mixing an oil phase with an aqueous phase in the presence of an emulsifier, wherein said emulsifier is a non-gelled branched polymer, wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm.

Abstract: An example exercise device includes an arm structure configured to pivot in response to a movement of at least a portion of a head of a user. An example method of exercising includes moving a portion of a head to pivot a weight arm that resists the moving.

Abstract: For processing messages in a messaging system comprising a source and a destination queue manager, an uncommitted message is received from an application at the source queue manager. This is transmitted to the destination queue manager and received thereat. When it is determined that the message is uncommitted, it is stored in memory, rather than placing the message on a receive queue for processing by another application. If it is determined that the uncommitted message has been committed by the application which originated the uncommitted message, then it is placed on the receive queue.

Abstract: An example apparatus for a user in a wheelchair includes an exercise device providing an exercise area configured to receive a wheelchair. A primary handle is moveable by a first user in the wheelchair from a first position to a second position. A resistance assembly opposes movement of the at least one primary handle. A spotter handle is coupled to move together with the at least one primary handle. The spotter handle accessible by a second user from a position outside the exercise area. An example exercise device for a user in a wheelchair includes an automatically adjustable pick.

Abstract: The present invention is an alignment device for a bag containing one or more ports. The alignment device is attached to either the one or more ports or to the bag adjacent the one or more ports. The plate has an indicator or a unique outer edge shape that is designed to fit into a corresponding unique opening in a holder to ensure proper alignment of the bag and its port(s) in the holder. The plate is has a series of holes equal to and in alignment with the one or more ports of the bag and the port(s) extend through the holes of the plate.

Abstract: The present invention is an alignment device for a bag containing one or more ports. The alignment device is attached to either the one or more ports or to the bag adjacent the one or more ports. The plate has an indicator or a unique outer edge shape that is designed to fit into a corresponding unique opening in a holder to ensure proper alignment of the bag and its port(s) in the holder. The plate is has a series of holes equal to and in alignment with the one or more ports of the bag and the port(s) extend through the holes of the plate.

Abstract: The present invention is an alignment device for a bag containing one or more ports. The alignment device is attached to either the one or more ports or to the bag adjacent the one or more ports. The plate has an indicator or a unique outer edge shape that is designed to fit into a corresponding unique opening in a holder to ensure proper alignment of the bag and its port(s) in the holder. The plate is has a series of holes equal to and in alignment with the one or more ports of the bag and the port(s) extend through the holes of the plate.

Abstract: The present invention is an alignment device for a bag containing one or more ports. The alignment device is attached to either the one or more ports or to the bag adjacent the one or more ports. The plate has an indicator or a unique outer edge shape that is designed to fit into a corresponding unique opening in a holder to ensure proper alignment of the bag and its port(s) in the holder. The plate is has a series of holes equal to and in alignment with the one or more ports of the bag and the port(s) extend through the holes of the plate.

Abstract: A method for providing atomicity for a unit of work involving a plurality of participants, the method comprising the steps of: sending a prepare request to at least one participant, wherein the request comprises data required for recovery purposes of the unit of work; and on recovery of the unit of work, recovering the unit of work comprising: obtaining the data from the at least one participant; and using the obtained data to recover and preserve the atomicity of the unit of work.