Abstract: Methods for determining the effect of a Clostridial neurotoxin on muscle are disclosed. In particular, methods for determining a potency and/or diffusion of a neurotoxin based on a nuclear index and/or an amount of muscle atrophy are disclosed. The methods may be used to distinguish two different Clostridial neurotoxins. In certain embodiments, the neurotoxins are obtained from Clostridium botulinum.

Abstract: This invention relates to the enzymatic synthesis of oligophenols on solid support by sequential enzymatic addition of reaction solutions containing phenols. The oligomers are then selectively built up on the solid surface. When used in a specific format, the oligomers can be generated in a spatially addressable array, which can then be screened for some type of biological interaction. The synthetic compounds of the present invention are synthesized in a combinatorial manner on solid support using peroxidase or other related enzymatic catalysis, and the products are generated in spatially addressable microarrays. Oligophenols of the present invention have shown significance as potential inhibitors of NADPH oxidase assembly, an enzyme that has been implicated in a wide range of diseases stemming from vascular hyperpermeability.

Abstract: A system for cooling electronic equipment, especially modular electronic units mounted in racks, each having a casing with an air inlet, an air outlet and a fan for cooling the contents of the unit. The system uses a chiller unit, between adjacent racks for returning cooled air to ambient, each of which can be a piping array connected to a supply of chilled water. A baffle backing the piping array improves heat exchange and provides a more uniform transfer of heat to each array, thereby enabling optimum temperature differences to be achieved across each rack. A slidable framework supports the piping array and defines an air space on the cooled air side of the array. An auxiliary piping array extends rearwardly of racks so as to communicate with rear air spaces behind the racks and thereby cool heated air flowing in the rear air spaces.

Abstract: A bow string release device comprises a rod shaped into a ring with a curved tail. The ring portion is placed upon the archer's middle finger and positioned near the finger's first joint. The tail is placed to the front of the bowstring and hooked or grasped by the index finger. The bowstring is then pulled back and released by the index finger letting go of the tail.

Abstract: The present invention relates to materials and methods for diagnosing breast cancer in humans. It is based, at least in part, on the discovery that a substantial percentage of human breast cancer tissue samples contained nucleic acid sequences corresponding to a portion of the mouse mammary tumor virus env gene. In contrast, such sequences were absent in almost all other human tissues tested.

Abstract: An amphibious water bomber float plane, wherein the water bomber plane is equipped with a pair of floats for landing and taking off on water, with wheels for use on land, and having pair of floats secured for supporting the plane on water, water tanks within the floats for accumulating water for water bombing, scoops mounted in each float for lowering and raising between lowered and raised positions, and, when in the lowered position, the scoops entering the surface of the water causing water to flow upwardly into the tanks, dump doors mounted in each float, in communication with the tanks, the dump doors being swingable between an open dumping position and a closed sealed position, and controls by which the dump doors may be operated from the plane. Also disclosed is a method of water bombing from an amphibious float plane.

Abstract: The present invention relates to materials and methods for diagnosing breast cancer in humans. It is based, at least in part, on the discovery that a substantial percentage of human breast cancer tissue samples contained nucleic acid sequences corresponding to a portion of the mouse mammary tumor env gene. In contrast, such sequences were absent in almost all other human tissues tested.