Patents by Inventor James Holmes

James Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10072291
    Abstract: The present invention is a biosensor apparatus that includes a substrate, a source on one side of the substrate, a drain spaced from the source, a conducting channel between the source and the drain, an insulator region, and receptors on a gate region for receiving target material. The receptors are contacted for changing current flow between the source and the drain. The source and the drain are relatively wide compared to length between the source and the drain through the conducting channel.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: September 11, 2018
    Assignee: UNIVERSITY OF HAWAII
    Inventor: James Holm-Kennedy
  • Patent number: 9957263
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided. The compounds are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Pharmaceutical compositions comprised of one or more compounds of formula (I) are also provided.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: May 1, 2018
    Assignee: AbbVie Inc.
    Inventors: Yujia Dai, Steven D. Fidanze, Lisa Hasvold, James Holms, Dachun Liu, William McClellan, Keith McDaniel, Jasmina Marjanovic, George Sheppard, Le Wang
  • Publication number: 20170354925
    Abstract: Techniques for distributing a liquid in a liquid-gas system include flowing a liquid into a system of nozzles and basin of the liquid-gas contacting system; and operating the nozzles and basin system with a distribution sub-assembly configured to operate the nozzles under a plurality of liquid flow rates and maintaining a consistent spatial liquid distribution of the liquid within the distribution sub-assembly at the plurality of liquid flow rates.
    Type: Application
    Filed: June 14, 2017
    Publication date: December 14, 2017
    Inventors: Kenton Robert Heidel, Geoffrey James Holmes, David W. Keith
  • Publication number: 20160272630
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided. The compounds are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Pharmaceutical compositions comprised of one or more compounds of formula (I) are also provided.
    Type: Application
    Filed: June 27, 2014
    Publication date: September 22, 2016
    Applicant: AbbVie Inc.
    Inventors: Yujia Dai, Steven D. Fidanze, Lisa Hasvold, James Holms, Dachun Liu, William McClellan, Keith McDaniel, Jasmina Marjanovic, George Sheppard, Le Wang
  • Publication number: 20160185769
    Abstract: The present invention provides for compounds of formula (I). wherein Rx, Ry, Rx1, L1, G1, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
    Type: Application
    Filed: May 13, 2014
    Publication date: June 30, 2016
    Applicant: Abbvie Inc.
    Inventors: Yujia Dai, Steven D. Fidanze, Lisa Hasvold, James Holms, Dachun Liu, William McClellan, Keith McDaniel, Jasmina Marjanovic, George Sheppard, Le Wang
  • Publication number: 20160002707
    Abstract: The present invention is a biosensor apparatus that includes a substrate, a source on one side of the substrate, a drain spaced from the source, a conducting channel between the source and the drain, an insulator region, and receptors on a gate region for receiving target material. The receptors are contacted for changing current flow between the source and the drain. The source and the drain are relatively wide compared to length between the source and the drain through the conducting channel.
    Type: Application
    Filed: July 14, 2015
    Publication date: January 7, 2016
    Inventor: James HOLM-KENNEDY
  • Patent number: 9109251
    Abstract: The present invention is a biosensor apparatus that includes a substrate, a source on one side of the substrate, a drain spaced from the source, a conducting channel between the source and the drain, an insulator region, and receptors on a gate region for receiving target material. The receptors are contacted for changing current flow between the source and the drain. The source and the drain are relatively wide compared to length between the source and the drain through the conducting channel.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: August 18, 2015
    Assignee: University of Hawaii
    Inventor: James Holm-Kennedy
  • Patent number: 9092394
    Abstract: A method or system for selecting or pruning applicable verbal commands associated with speech recognition based on a user's motions detected from a depth camera. Depending on the depth of the user's hand or arm, the context of the verbal command is determined and verbal commands corresponding to the determined context are selected. Speech recognition is then performed on an audio signal using the selected verbal commands. By using an appropriate set of verbal commands, the accuracy of the speech recognition is increased.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: July 28, 2015
    Assignee: Honda Motor Co., Ltd.
    Inventors: Tarek El Dokor, James Holmes, Jordan Cluster, Stuart Yamamoto, Pedram Vaghefinazari
  • Publication number: 20150017706
    Abstract: Enhancing growth of algae in an algaculture facility includes contacting a growth medium with a gas including carbon dioxide, transferring some of the carbon dioxide to the growth medium to yield an enriched growth medium, and providing the enriched growth medium to the algaculture facility. The concentration of dissolved carbon dioxide in the enriched growth medium exceeds the concentration of dissolved carbon dioxide in the growth medium, where dissolved carbon dioxide includes ions formed by the reaction of carbon dioxide with a species in solution. The growth medium may be obtained from the algaculture facility, and may be filtered or otherwise processed before or after contacting the growth medium with the gas. Providing the enriched growth medium to the algaculture facility increases the concentration of dissolved carbon dioxide in the bulk growth medium of the algaculture facility.
    Type: Application
    Filed: February 8, 2013
    Publication date: January 15, 2015
    Inventors: Arvinder Pal Singh Kainth, Kenton Robert Heidel, Matthew Alex Henderson, Geoffrey James Holmes, Jane Anne Ritchie, David William Keith
  • Patent number: 8890522
    Abstract: The present disclosure is intended to describe embodiments for improving image data acquisition and processing in accelerated dynamic magnetic resonance imaging sequences. One embodiment is described where a method includes an acquisition sequence configured to acquire an undersampled set of magnetic resonance data. The undersampled set of magnetic resonance data has a pseudo-random sampling pattern within a data space acquired at a first time, the pseudo-random sampling pattern being influenced by other pseudo-random sampling patterns within the data space arising from the acquisition of additional undersampled sets of magnetic resonance data at respective times. In some embodiments, the pseudo-random sampling patterns of the undersampled sets of magnetic resonance data interleave to yield a desired sampling pattern.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: November 18, 2014
    Assignee: General Electric Company
    Inventors: Reed Frederick Busse, James Holmes, Philip James Beatty, Kang Wang, Frank Korosec
  • Patent number: 8874109
    Abstract: A method and system automatically activates a mobile station in a wireless communications network. The system includes an over the air activation function (OTAF) processor in the network that initiates an activation process in response to receiving a registration message from a mobile switching center serving the mobile station requesting the activation. Each mobile station has a unit of information stored into it at the time of its manufacture to enable it to request over the air activation. That unit of information is either the network routing address of the OTAF processor, or alternately, it is a value that is translatable into that address, either an OTAF ID number that is the same value for every mobile station or it is a sequentially serialized dummy value for the mobile identification number (a dummy MIN).
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: October 28, 2014
    Assignee: AT&T Mobility II LLC
    Inventors: Arun K. Chatterjee, Brian Kevin Daly, David William James Holmes, Ileana A. Leuca
  • Patent number: 8870171
    Abstract: The present application provides an extraction system for removing a retaining pin from a turbine engine. The extraction system may include a pin extraction fixture and a drill such that the pin extraction fixture positions the drill about the retaining pin. The pin extraction fixture may include a collet and one or more expanders positioned thereabout.
    Type: Grant
    Filed: February 14, 2011
    Date of Patent: October 28, 2014
    Assignee: General Electric Company
    Inventors: John Herbold, Paul Kalmar, Randall Corn, James Holmes
  • Patent number: 8653817
    Abstract: The present disclosure is intended to describe embodiments for improving image data acquisition and processing in accelerated dynamic magnetic resonance imaging sequences. One embodiment is described where a method includes an acquisition sequence configured to acquire an undersampled set of magnetic resonance data. The undersampled set of magnetic resonance data has a pseudo-random sampling pattern within a data space acquired at a first time, the pseudo-random sampling pattern being influenced by other pseudo-random sampling patterns within the data space arising from the acquisition of additional undersampled sets of magnetic resonance data at respective times. In some embodiments, the pseudo-random sampling patterns of the undersampled sets of magnetic resonance data interleave to yield a desired sampling pattern.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: February 18, 2014
    Assignee: General Electric Company
    Inventors: Reed Frederick Busse, James Holmes, Philip James Beatty, Kang Wang, Frank Korosec
  • Publication number: 20130339027
    Abstract: A method or system for selecting or pruning applicable verbal commands associated with speech recognition based on a user's motions detected from a depth camera. Depending on the depth of the user's hand or arm, the context of the verbal command is determined and verbal commands corresponding to the determined context are selected. Speech recognition is then performed on an audio signal using the selected verbal commands. By using an appropriate set of verbal commands, the accuracy of the speech recognition is increased.
    Type: Application
    Filed: June 15, 2012
    Publication date: December 19, 2013
    Inventors: Tarek El Dokor, James Holmes, Jordan Cluster, Stuart Yamamoto, Pedram Vaghefinazari
  • Publication number: 20130331102
    Abstract: A method and system automatically activates a mobile station in a wireless communications network. The system includes an over the air activation function (OTAF) processor in the network that initiates an activation process in response to receiving a registration message from a mobile switching center serving the mobile station requesting the activation. Each mobile station has a unit of information stored into it at the time of its manufacture to enable it to request over the air activation. That unit of information is either the network routing address of the OTAF processor, or alternately, it is a value that is translatable into that address, either an OTAF ID number that is the same value for every mobile station or it is a sequentially serialized dummy value for the mobile identification number (a dummy MIN).
    Type: Application
    Filed: August 19, 2013
    Publication date: December 12, 2013
    Applicant: AT&T Mobility II LLC
    Inventors: Arun K. Chatterjee, Brian Kevin Daly, David William James Holmes, Ileana A. Leuca
  • Patent number: 8593051
    Abstract: Apparatus for the production of a charged particle beam, comprising: an ion source plasma chamber (104), having a door (106), and an accelerator (102) mounted on the face of the door remote from the ion source plasma chamber.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: November 26, 2013
    Assignee: Nordiko Technical Services Limited
    Inventors: Timothy Andrew James Holmes, Mervyn Howard Davis
  • Patent number: 8515423
    Abstract: A method and system automatically activates a mobile station in a wireless communications network. The system includes an over the air activation function (OTAF) processor in the network that initiates an activation process in response to receiving a registration message from a mobile switching center serving the mobile station requesting the activation. Each mobile station has a unit of information stored into it at the time of its manufacture to enable it to request over the air activation. That unit of information is either the network routing address of the OTAF processor, or alternately, it is a value that is translatable into that address, either an OTAF ID number that is the same value for every mobile station or it is a sequentially serialized dummy value for the mobile identification number (a dummy MIN).
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 20, 2013
    Assignee: AT&T Mobility II LLC
    Inventors: Arun K. Chatterjee, Brian Kevin Daly, David William James Holmes, Ileana A. Leuca
  • Patent number: 8435980
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, R1c, X, and Y are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: May 7, 2013
    Assignee: AbbVie Inc.
    Inventors: Alan S. Florjancic, Yunsong Tong, Thomas D. Penning, Jane Gong, Magdalena Przytulinska, Douglas Steinman, James Holms, Chunqiu Lai, Gui-Dong Zhu, Keith Woods
  • Patent number: 8301140
    Abstract: A method and system automatically activates a mobile station in a wireless communications network. The system includes an over the air activation function (OTAF) processor in the network that initiates an activation process in response to receiving a registration message from a mobile switching center serving the mobile station requesting the activation. Each mobile station has a unit of information stored into it at the time of its manufacture to enable it to request over the air activation. That unit of information is either the network routing address of the OTAF processor, or alternately, it is a value that is translatable into that address, either an OTAF ID number that is the same value for every mobile station or it is a sequentially serialized dummy value for the mobile identification number (a dummy MIN). When the mobile station is turned on for the first time in the network, it requests activation over the air by transmitting to the local mobile switching center a registration order.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: October 30, 2012
    Assignee: AT&T Mobility II LLC
    Inventors: Arun K. Chatterjee, Brian Kevin Daly, David William James Holmes, Ileana A. Leuca
  • Patent number: 8293085
    Abstract: A cartridge for an ion exchanging electrochemical cell, the cartridge comprising at least one spiral wound, textured, bipolar ion exchange membrane having (i) an anion exchange layer abutting a cation exchange layer with continuous contact between the anion exchange layer and the cation exchange layer; and (ii) an exposed textured surface having a pattern of texture features. A method of manufacturing a cartridge for an ion exchange electrochemical cell comprises winding the textured, bipolar ion exchange membrane into a spiral wound membrane.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: October 23, 2012
    Assignee: Pionetics Corporation
    Inventors: John Hawkins, Eric Nyberg, George Kayser, James Holmes, Paul Schoenstein, Ashok Janah