Abstract: A multi-lumen catheter includes a primary lumen having a proximal end and a tip and a secondary lumen parallel to the primary lumen. The primary lumen and the secondary lumen share a wall. A port is defined in the wall proximate the tip of the primary lumen and provides fluidic communication between the primary lumen and the secondary lumen.

Abstract: A catheter includes an elongated tube having a distal end and a proximal end. The elongated tube includes porous material having an interior and an exterior face. The interior face defines a lumen along a central axis of the elongated tube. The porous material is configured to flow a fluid between the interior face and the exterior face and to seep the fluid out of the porous material through the exterior face and interior face. A lining covers at least a portion of the exterior face and substantially limits perfusion through the exterior face at the portion of the exterior face covered by the lining. The catheter is impregnated with a material that prevents buildup of material on one of an inner face or an outer face of the catheter or the lining is coated with one or more of an anticoagulant, antibiotic, or antithrombotic.

Abstract: A multi-lumen catheter includes a primary lumen having a proximal end and a tip and a secondary lumen parallel to the primary lumen. The primary lumen and the secondary lumen share a wall. A port is defined in the wall proximate the tip of the primary lumen and provides fluidic communication between the primary lumen and the secondary lumen.

Abstract: A catheter includes an elongated tube having a distal end and a proximal end. The elongated tube includes porous material having an interior and an exterior face. The interior face defines a lumen along a central axis of the elongated tube. The porous material is configured to flow a fluid between the interior face and the exterior face and to seep the fluid out of the porous material through the exterior face and interior face. A lining covers at least a portion of the exterior face and substantially limits perfusion through the exterior face at the portion of the exterior face covered by the lining. The catheter is impregnated with a material that prevents buildup of material on one of an inner face or an outer face of the catheter or the lining is coated with one or more of an anticoagulant, antibiotic, or antithrombotic.

Abstract: The device and methods described herein relate to a seeping flow catheter. The seeping flow catheter includes a porous material. The inner face of the porous material defines the lumen of the catheter. The porous material is configured such that fluid can flow along the length of the catheter, between the inner face and outer face of the porous material. As the fluid flows through the porous material, the fluid can seep into the lumen of the catheter through the inner face or out of the catheter through the outer face of the porous material. Portions of the inner or outer face can include a lining that substantial reduces the perfusion of the fluid through the lined areas.

Abstract: The device and methods described herein relate to a seeping flow catheter. The seeping flow catheter includes a porous material. The inner face of the porous material defines the lumen of the catheter. The porous material is configured such that fluid can flow along the length of the catheter, between the inner face and outer face of the porous material. As the fluid flows through the porous material, the fluid can seep into the lumen of the catheter through the inner face or out of the catheter through the outer face of the porous material. Portions of the inner or outer face can include a lining that substantial reduces the perfusion of the fluid through the lined areas.

Abstract: A scaffold defines a plurality of channels, into which axons of a severed nerve may regenerate, such as after limb amputation. Each channel includes a corresponding electrode. Regenerating axons may make electrical contact with the electrodes. Each channel is at least partially filled with a growth factor selected to selectively stimulate axon regeneration. Adjacent channels may include different growth factors, so as to attract different types of axons, for example efferent axons and afferent axons, to each of the adjacent channels. The growth factors may be distributed in the channels so as to present a gradient across a geometry of each channel. This gradient provides enhanced differentiated geometric guidance to the axons, thereby yielding better specificity, in terms of which axons regenerate into which channels. Topography, such as geometric patterns in walls, ceilings and floors of the channels, may also be used to selectively encourage axon regeneration into the channels.

Abstract: A scaffold defines a plurality of channels, into which axons of a severed nerve may regenerate, such as after limb amputation. Each channel includes a corresponding electrode. Regenerating axons may make electrical contact with the electrodes. Each channel is at least partially filled with a growth factor selected to selectively stimulate axon regeneration. Adjacent channels may include different growth factors, so as to attract different types of axons, for example efferent axons and afferent axons, to each of the adjacent channels. The growth factors may be distributed in the channels so as to present a gradient across a geometry of each channel. This gradient provides enhanced differentiated geometric guidance to the axons, thereby yielding better specificity, in terms of which axons regenerate into which channels. Topography, such as geometric patterns in walls, ceilings and floors of the channels, may also be used to selectively encourage axon regeneration into the channels.

Abstract: A multipurpose ladder accessory assembly for a ladder having a top rung, a penultimate rung and a multiple of lower rungs each extending between a first elongated ladder rail and a second elongated ladder rail defining ladder rails, each ladder rail having an upper end and a lower end, said accessory assembly comprising a first and second pair of ladder accessory arms each defining a first arm connected to the first ladder rail between the upper end of the first ladder rail and the penultimate rung, and a second arm connected to the second ladder rail between the upper end of the second ladder rail and the penultimate rung, such that each of the first arms and the second arms of the first and the second pair of ladder accessory arms are independently moveable from a folded position along the ladder rails to an extended position from the ladder rails.