Patents by Inventor James Huang

James Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200095934
    Abstract: A fluid passage assembly and method for manufacturing a fluid passage assembly for a power generator. The fluid passage assembly includes a manifold body having an inlet conduit for receiving a fluid, and at least one distribution conduit fluidly coupled to the inlet conduit for dispensing the fluid to cool the power generator, wherein a cross-section of the at least one distribution conduit is includes at least one corner.
    Type: Application
    Filed: September 25, 2018
    Publication date: March 26, 2020
    Inventors: Merin Sebastian, Qizhou Matthew Yao, Indira Priyadarsini Rallabandi, Narendra Dev Mahadevaiah, James Patrick Mahle, Hao Huang
  • Publication number: 20200095231
    Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
    Type: Application
    Filed: May 10, 2018
    Publication date: March 26, 2020
    Inventors: James Aaron BALOG, Emily Charlotte CHERNEY, Liping ZHANG, Audris HUANG, Weifang SHAN, David K. WILLIAMS, Xiao ZHU, Weiwei GUO
  • Publication number: 20200095889
    Abstract: A heat-carrying component can include an outer casing bounding an interior, where a conduit can be located within the interior. A support structure can also be located within the interior and support the conduit. In addition, the support structure can include at least two thermally-conductive support members supporting the conduit.
    Type: Application
    Filed: September 26, 2018
    Publication date: March 26, 2020
    Inventors: Merin Sebastian, James Patrick Mahle, Qizhou Matthew Yao, Indira Priyadarsini Rallabandi, Narendra Dev Mahadevaiah, Hao Huang
  • Patent number: 10595668
    Abstract: An apparatus and method for sharing capsule image data and beverage preparation parameters, from one or more beverage preparation machines with a remote computer system via a network, such as the Internet, is disclosed. The remote computer system may process the capsule image data to determine characteristics of the capsule (e.g., a type of capsule, such as a brand, or beverage ingredients in the capsule), thereby relieving the beverage preparation from having to determine information about the capsule. The remote computer may track a user's consumption of capsules, may compare this value to the user's past capsule purchase history, and may determine if the user's supply of capsules is below a threshold value (e.g., below a week's worth of capsules).
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: March 24, 2020
    Assignee: Keurig Green Mountain, Inc.
    Inventors: Ian Tinkler, Jianming Huang, Kevin William Hartley, Cameron McLeod, Samuel Ross Rulli, Nicholas George Ioannidis, James K. Lynch, Brian David Rheaume, Jeffrey Sol Hadden, Philip Hadley, Yvona Hlobilova
  • Publication number: 20200088884
    Abstract: A vehicle, Lidar system and method of detecting an object is disclosed. The Lidar system includes a photonic chip, and a laser integrated into the photonic chip. The laser has a front facet located at a first aperture of the photonic chip to direct a transmitted light beam into free space. A reflected light beam that is a reflection of the transmitted light beam is received at the photonic chip and a parameter of the object is determined from a comparison of the transmitted light beam and the reflected light beam. A navigation system operates the vehicle with respect to the object based on a parameter of the object.
    Type: Application
    Filed: August 28, 2019
    Publication date: March 19, 2020
    Inventors: Keyvan Sayyah, Oleg Efimov, Biqin Huang, Raymond Sarkissian, James H. Schaffner, David Hammon, Richard Kremer, Timothy J. Talty, Michael Mulqueen, Pamela R. Patterson
  • Publication number: 20200088845
    Abstract: A Lidar system, photonic chip and method of detecting an object is disclosed. The Lidar system includes the photonic chip. The photonic chip includes a laser and a local oscillator waveguide. The laser is integrated into the photonic chip and generates a leakage energy at a back facet of the laser for use as a local oscillator beam for the photonic chip. The local oscillator waveguide receives the leakage energy as the local oscillator beam. The laser further generates a transmitted light beam through a front facet of the photonic chip, combining the leakage energy with a reflection of the transmitted light beam form an object, and detects a combination of the reflected light beam and the leakage energy to determine a parameter of the object.
    Type: Application
    Filed: August 29, 2019
    Publication date: March 19, 2020
    Inventors: Timothy J. Talty, Oleg Efimov, Michael Mulqueen, Keyvan Sayyah, Pamela R. Patterson, Raymond Sarkissian, James H. Schaffner, David Hammon, Biqin Huang
  • Patent number: 10594984
    Abstract: Embodiments of the present invention relate to a computer program product, an apparatus and a method for monitoring a target object by multiple cameras by building a surveillance network based on attributes of the multiple cameras, the surveillance network describing reachability between locations of the multiple cameras; and in response to determining that the target object is detected at a first camera among the multiple cameras, monitoring the target object based on the reachability between locations of the multiple cameras.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: March 17, 2020
    Assignee: EMC IP Holding Company LLC
    Inventors: Grissom Tianqing Wang, Roby Qiyan Chen, Bo Huang, Yicang Wu, James Zhongxiang Xiong
  • Publication number: 20200079877
    Abstract: The present disclosure provides anti-CD73 binding molecules, e.g., antibodies and antigen binding fragments thereof. Also provided are pharmaceutical formulations comprising the disclosed compositions, and methods for the diagnosis and treatment of diseases associated with CD73-expression, e.g., cancer. Such diseases can be treated, e.g., by direct therapy with the anti-CD73 binding molecules disclosed herein (e.g., naked antibodies or antibody-drug conjugates that bind CD73), by adjuvant therapy with other antigen-binding anticancer agents such as immune checkpoint inhibitors (e.g., anti-CTLA-4 and anti-PD-1 monoclonal antibodies), and/or by combination therapies where the anti-CD73 molecules are administered before, after, or concurrently with chemotherapy.
    Type: Application
    Filed: November 8, 2019
    Publication date: March 12, 2020
    Inventors: Carl HAY, Kris SACHSENMEIER, Erin SULT, Qihui Huang, Peter PAVLIK, Melissa DAMSCHRODER, Li CHENG, Gundo DIEDRICH, Jonathan RIOS-DORIA, Scott HAMMOND, Ralph MINTER, Steve RUST, Sandrine GUILLARD, Robert HOLLINGSWORTH, Lutz JERMUTUS, Nicholas DURHAM, Ching Ching LEOW, Mary ANTONYSAMY, James GEOGHEGAN, Xiaojun LU, Kim ROSENTHAL
  • Publication number: 20200073438
    Abstract: A dock for a portable electronic device includes a base and an arm movably supported on the base. The arm has a ratchet gear set and a distal end configured to engage the portable electronic device to secure the portable electronic device to the base. The dock further includes a ratchet pawl positioned within the base. The ratchet pawl is movable between a first position, in which the ratchet pawl engages the ratchet gear set to inhibit movement of the arm relative to the base, and a second position, in which the ratchet pawl disengages the ratchet gear set to allow movement of the arm relative to the base. The dock further includes an electronic actuator operable to actuate the ratchet pawl from the first position to the second position.
    Type: Application
    Filed: September 5, 2018
    Publication date: March 5, 2020
    Inventors: Yu-Chia Huang, Alex James Klinkman
  • Publication number: 20200062759
    Abstract: The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.
    Type: Application
    Filed: March 4, 2019
    Publication date: February 27, 2020
    Inventors: Pankaj Pasricha, Yifang Huang, James Barrow
  • Publication number: 20200048744
    Abstract: The disclosure provides an aluminum alloy may include iron (Fe) of at least 0.10 wt %, silicon (Si) of at least 0.35 wt %, and magnesium (Mg) of at least 0.45 wt %, manganese (Mn) in amount of at least 0.005 wt %, and additional elements, the remaining wt % being Al and incidental impurities.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 13, 2020
    Inventors: Brian M. Gable, Herng-Jeng Jou, Weiming Huang, Graeme W. Paul, William A. Counts, Eric W. Hamann, Katie L. Sassaman, Abhijeet Misra, Zechariah D. Feinberg, James A. Yurko, Brian P. Demers, Rafael Yu, Anuj Datta Roy, Susannah P. Calvin
  • Patent number: 10559939
    Abstract: Laser diode technology incorporating etched facet mirror formation and optical coating techniques for reflectivity modification to enable ultra-high catastrophic optical mirror damage thresholds for high power laser diodes.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: February 11, 2020
    Assignee: Soraa Laser Diode, Inc.
    Inventors: James W. Raring, Hua Huang, Phillip Skahan, Sang-Ho Oh, Ben Yonkee, Alexander Sztein, Qiyuan Wei
  • Patent number: 10556968
    Abstract: The present disclosure provides anti-CD73 binding molecules, e.g., antibodies and antigen binding fragments thereof. Also provided are pharmaceutical formulations comprising the disclosed compositions, and methods for the diagnosis and treatment of diseases associated with CD73-expression, e.g., cancer. Such diseases can be treated, e.g., by direct therapy with the anti-CD73 binding molecules disclosed herein (e.g., naked antibodies or antibody-drug conjugates that bind CD73), by adjuvant therapy with other antigen-binding anticancer agents such as immune checkpoint inhibitors (e.g., anti-CTLA-4 and anti-PD-1 monoclonal antibodies), and/or by combination therapies where the anti-CD73 molecules are administered before, after, or concurrently with chemotherapy.
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: February 11, 2020
    Assignee: MEDIMMUNE LIMITED
    Inventors: Carl Hay, Kris Sachsenmeier, Erin Sult, Qihui Huang, Peter Pavlik, Melissa Damschroder, Li Cheng, Gundo Diedrich, Jonathan Rios-Doria, Scott Hammond, Ralph Minter, Steve Rust, Sandrine Guillard, Robert Hollingsworth, Lutz Jermutus, Nicholas Durham, Ching Ching Leow, Mary Antonysamy, James Geoghegan, Xiaojun Lu, Kim Rosenthal
  • Publication number: 20200039914
    Abstract: Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, A, W, L, Ra, and G are defined herein: and by Formula (II) as follows: wherein R1B, WB, LB, , and GB are defined herein.
    Type: Application
    Filed: October 24, 2017
    Publication date: February 6, 2020
    Inventors: Hui Huang, James C. Lanter, Sanath K. Meegalla, Mark R. Player
  • Patent number: 10549255
    Abstract: Methods, compositions, devices and kits having a novel chromatographic material are provided herein for separating and identifying organic molecules and compounds, for example molecules and compounds containing electron rich functional groups such as carbon-carbon double bonds. The methods, compositions, and kits include a metal-thiolate chromatographic medium (MTCM) with a sulfur-containing functional group or a metal-selenolate chromatographic medium (MSCM) comprising a selenium-containing functional group covalently attached to a support medium, such that the sulfur-containing functional group or selenium-containing functional group is bound to at least one metal atom. The MTCM and/or MSCM has affinity and specificity to compounds having one or more carbon-carbon double bonds, and performs a highly efficient and rapid separation of samples yielding non-overlapping peaks of purified materials compared to traditional media.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: February 4, 2020
    Assignee: BROWN UNIVERSITY
    Inventors: Yongsong Huang, Jose C. Aponte, Rafael Tarozo, James Dillon
  • Publication number: 20200031692
    Abstract: An electrode for use in bio-electrochemical systems is described, including: a substantially planar electrode material; a frame comprising a non-conductive substance; and one or more first conductive substances linked or secured to the frame. Bio-electrochemical systems, racks for inserting the electrode, and methods of using the racks are also described.
    Type: Application
    Filed: August 5, 2019
    Publication date: January 30, 2020
    Applicant: Cambrian Innovation, Inc.
    Inventors: Matthew Silver, Justin Buck, Casey Chartier, Mark Barosky, James Ryan Hawkins, Zhen Huang, Quynh Anh Le Tran, Tzipora Wagner
  • Publication number: 20200030325
    Abstract: The present invention relates to novel “reverse amide” compounds comprising a zinc chelator group, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.
    Type: Application
    Filed: August 26, 2019
    Publication date: January 30, 2020
    Inventors: John H. van Duzer, Ralph Mazitschek, Walter Olgier, James E. Bradner, Guoxiang Huang, Dejian Xie, Nan Yu
  • Patent number: 10538815
    Abstract: Provided herein is technology relating to detecting molecular markers relevant to cancer and particularly, but not exclusively, to methods and compositions for quantifying and/or detecting EGFR mRNA and/or EGFRvIII mRNA in biological samples.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: January 21, 2020
    Assignee: ABBOTT MOLECULAR INC.
    Inventors: Jeffrey D. Wuitschick, Kevin S. Nelson, Shihai Huang, Rupinder Kular, Carolyn Mullen, James Rhoads
  • Patent number: 10533014
    Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: January 14, 2020
    Assignee: FLEXUS BIOSCIENCES, INC.
    Inventors: Hilary Plake Beck, Juan Carlos Jaen, Maksim Osipov, Jay Patrick Powers, Maureen Kay Reilly, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky, James Aaron Balog, David K. Williams, Jay A. Markwalder, Emily Charlotte Cherney, Weifang Shan, Audris Huang
  • Patent number: D879967
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: March 31, 2020
    Assignee: Mar Cor Purification, Inc.
    Inventors: Michael L. Verguldi, Garry O. Miller, James Huang Lua, Ryan Robert Berger, Jeffrey R. Burger