Patents by Inventor James Hurley

James Hurley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12378608
    Abstract: The present disclosure relates to methods for detecting and treating bladder cancer in a subject using the gene expression level measurements from exosomes derived from the subject.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: August 5, 2025
    Assignee: Exosome Diagnostics, Inc.
    Inventors: Robert Kitchen, Elena Castellanos-Rizaldos, Mia Sher, James Hurley, Dalin Chan, Georg Stoll, Wei Yu, Johan Skog
  • Patent number: 12317000
    Abstract: Described are systems and methods for providing a publisher-subscriber architecture for audio and/or video conferencing. Embodiments of the present disclosure can utilize one edge computing resources associated with each client device participating in the audio and/or video conference. One or more client devices can publish streams to the associated edge computing resources. The streams can then be pushed via a data network to the edge computing resources associated with the subscribing client devices. The subscribing client devices can access and fetch the streams from the edge computing resources, which can be presented on the client devices as part of a conferencing session experience.
    Type: Grant
    Filed: December 20, 2023
    Date of Patent: May 27, 2025
    Assignee: Amazon Technologies, Inc.
    Inventors: Sean Patrick DuBois, Christopher LaFata, James Hurley, Raymond Kung Hsien Lin, Alex Converse, Adam Lupinacci, Maxwell Stoller, James Yamat
  • Publication number: 20250163510
    Abstract: The present disclosure relates to methods of identifying and treating kidney rejection in a subject comprising analyzing RNA, including microvesicular RNA.
    Type: Application
    Filed: February 21, 2023
    Publication date: May 22, 2025
    Inventors: Johan Karl Olov SKOG, Brian C. HAYNES, Elliot HALLMARK, James HURLEY, Jamil AZZI
  • Patent number: 12286579
    Abstract: A two-part flame-retardant, a flame-retardant oriented strand (OSB) and method for forming a flame-retardant OSB is provided. The two-part flame-retardant composition includes an aqueous solution containing a water-soluble flame-retardant and a flame-retardant powder that is incorporated into an oriented strand board without substantially affecting the mechanical properties of the oriented strand board. The method includes applying the aqueous solution containing a water-soluble flame-retardant to an oriented strand board furnish and applying a flame-retardant powder to the wetted furnish, without requiring an additional drying step.
    Type: Grant
    Filed: July 7, 2022
    Date of Patent: April 29, 2025
    Assignee: ARXADA, LLC
    Inventors: Lehong Jin, David Humphrey, Ghonche Rassam, Olivera Zivkovic, Adegoke Adekunle, James Hurley, Susan Thomason
  • Patent number: 12054661
    Abstract: A two-part flame-retardant, a flame-retardant oriented strand (OSB) and method for forming a flame-retardant OSB is provided. The two-part flame-retardant composition includes an aqueous solution containing a water-soluble flame-retardant and a flame-retardant powder that is incorporated into an oriented strand board without substantially affecting the mechanical properties of the oriented strand board. The method includes applying the aqueous solution containing a water-soluble flame-retardant to an oriented strand board furnish and applying a flame-retardant powder to the wetted furnish, without requiring an additional drying step.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: August 6, 2024
    Assignee: Arxada, LLC
    Inventors: Lehong Jin, David Humphrey, Ghonche Rassam, Olivera Zivkovic, Adegoke Adekunle, James Hurley, Susan Thomason
  • Patent number: 11910131
    Abstract: Described are systems and methods for providing a publisher-subscriber architecture for audio and/or video conferencing. Embodiments of the present disclosure can utilize one edge computing resource associated with each client device participating in the audio and/or video conference. One or more client devices can publish streams to the associated edge computing resources. The streams can then be pushed, via a data network, to the edge computing resources associated with the subscribing client devices. The subscribing client devices can access and fetch the streams from the edge computing resources, which can be presented on the client devices as part of a conferencing session experience.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: February 20, 2024
    Assignee: Amazon Technologies, Inc.
    Inventors: Sean Patrick DuBois, Christopher LaFata, James Hurley, Raymond Kung Hsien Lin, Alex Converse, Adam Lupinacci, Maxwell Stoller, James Yamat
  • Patent number: 11891664
    Abstract: The invention relates generally to the use of microvesicle biomarkers such as nucleic acids, including nucleic acid signatures, and/or proteins for assessing a kidney transplant rejection in a patient. The invention further relates to assessing, and/or to monitoring kidney transplant rejection in patients who have received a renal transplant.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: February 6, 2024
    Assignees: Exosome Diagnostics, Inc., The Brigham and Women's Hospital
    Inventors: James Hurley, Christine Coticchia, Robert Kitchen, Vasisht Tadigotla, Johan Karl Olov Skog, Jamil Azzi
  • Publication number: 20230203587
    Abstract: The present disclosure relates to methods of identifying and treating kidney rejection in a subject comprising analyzing microvesicular RNA, cell-free DNA or the combination of microvesicular and cell-free DNA.
    Type: Application
    Filed: May 28, 2021
    Publication date: June 29, 2023
    Inventors: Johan SKOG, Vasisht TADIGOTLA, James HURLEY, Jamil AZZI
  • Publication number: 20220340816
    Abstract: A two-part flame-retardant, a flame-retardant oriented strand (OSB) and method for forming a flame-retardant OSB is provided. The two-part flame-retardant composition includes an aqueous solution containing a water-soluble flame-retardant and a flame-retardant powder that is incorporated into an oriented strand board without substantially affecting the mechanical properties of the oriented strand board. The method includes applying the aqueous solution containing a water-soluble flame-retardant to an oriented strand board furnish and applying a flame-retardant powder to the wetted furnish, without requiring an additional drying step.
    Type: Application
    Filed: July 7, 2022
    Publication date: October 27, 2022
    Inventors: Lehong Jin, David Humphrey, Ghonche Rassam, Olivera Zivkovic, Adegoke Adekunle, James Hurley, Susan Thomason
  • Patent number: 11414602
    Abstract: A two-part flame-retardant, a flame-retardant oriented strand (OSB) and method for forming a flame-retardant OSB is provided. The two-part flame-retardant composition includes an aqueous solution containing a water-soluble flame-retardant and a flame-retardant powder that is incorporated into an oriented strand board without substantially affecting the mechanical properties of the oriented strand board. The method includes applying the aqueous solution containing a water-soluble flame-retardant to an oriented strand board furnish and applying a flame-retardant powder to the wetted furnish, without requiring an additional drying step.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: August 16, 2022
    Assignee: ARXADA, LLC
    Inventors: Lehong Jin, David Humphrey, Ghonche Rassam, Olivera Zivkovic, Adegoke Adekunle, James Hurley, Susan Thomason
  • Publication number: 20220204781
    Abstract: A two-part flame-retardant, a flame-retardant oriented strand (OSB) and method for forming a flame-retardant OSB is provided. The two-part flame-retardant composition includes an aqueous solution containing a water-soluble flame-retardant and a flame-retardant powder that is incorporated into an oriented strand board without substantially affecting the mechanical properties of the oriented strand board. The method includes applying the aqueous solution containing a water-soluble flame-retardant to an oriented strand board furnish and applying a flame-retardant powder to the wetted furnish, without requiring an additional drying step.
    Type: Application
    Filed: June 15, 2020
    Publication date: June 30, 2022
    Inventors: Lehong JIN, David HUMPHREY, Ghonche RASSAM, Olivera ZIVKOVIC, Adegoke ADEKUNLE, James HURLEY, Susan THOMASON
  • Patent number: 11345957
    Abstract: The present disclosure relates to methods for treating glioblastoma in a subject in need thereof using gene signatures in exosomal RNA derived from the subject. The gene signatures comprise: at least one of FAM229B, ZNF35, CTD-2647L4.4, CABP5, CYP20A1, CEP126, DTX2P1-UPK3BP1-PMS2P11, RP11-507K12.1, KRBA2, CALD1, LRFN1, RP2, SLC2A13, CDKL3, SLC8A3, ANTXR2, TIGD5, AC074289.1 RP11-932O9.7; at least one of tRNA-Lys-CTT-2-2, tRNA-Pro-AGG-2-7, LAMTOR2, RAD51AP1, DENND2A, A1BG, THSD1, CSF1, RP11-332M2.1, ZNF717, ZNF860, ORC6, Clorf50, PSPH, HIST1H4C, CYP2U1, THAP8, TMEM192, NAA20; or at least one of CREBBP, CXCR2 and S100A9. The treatment methods comprise measuring the expression level of at least one of the aforementioned genes in exosomal RNA from a subject and administering to the subject a glioblastoma treatment based on the expression level(s).
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: May 31, 2022
    Assignee: Exosome Diagnostics, Inc.
    Inventors: Robert Kitchen, Michael Valentino, Johan Skog, Vasisht Tadigotla, Dalin Chan, Sudipto Chakrabortty, James Hurley
  • Publication number: 20210230701
    Abstract: The present disclosure relates to methods for detecting and treating bladder cancer in a subject using the gene expression level measurements from exosomes derived from the subject.
    Type: Application
    Filed: June 6, 2019
    Publication date: July 29, 2021
    Inventors: Robert KITCHEN, Elena CASTELLANOS-RIZALDOS, Mia SHER, James HURLEY, Dalin CHAN, Georg STOLL, Wei YU, Johan SKOG
  • Patent number: 10874926
    Abstract: A golf club that is used to practice a golf swing. Specifically, the golf club includes a handle and a head coupled to the handle. The head is formed from a first portion and a second portion that are coupled together. The first portion may be formed of a rigid material and the second portion may be formed of a resilient material. The second portion may comprise bristles or some other soft, pliable, compressible material that will not damage a surface upon contact during swinging the golf club. The golf club head preferably has the same shape as a traditional golf club head of the same type. However, the second portion forms the sole of the head, thereby eliminating the potential for damage to a floor surface during swinging of the golf club.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: December 29, 2020
    Inventor: James Hurley
  • Publication number: 20200392412
    Abstract: A two-part flame-retardant, a flame-retardant oriented strand (OSB) and method for forming a flame-retardant OSB is provided. The two-part flame-retardant composition includes an aqueous solution containing a water-soluble flame-retardant and a flame-retardant powder that is incorporated into an oriented strand board without substantially affecting the mechanical properties of the oriented strand board. The method includes applying the aqueous solution containing a water-soluble flame-retardant to an oriented strand board furnish and applying a flame-retardant powder to the wetted furnish, without requiring an additional drying step.
    Type: Application
    Filed: June 15, 2020
    Publication date: December 17, 2020
    Inventors: Lehong Jin, David Humphrey, Ghonche Rassam, Olivera Zivkovic, Adegoke Adekunle, James Hurley, Susan Thomason
  • Publication number: 20200224245
    Abstract: The present disclosure relates to methods for providing a clinical assessment of a subject in need thereof using the gene expression level measurements from exosomes derived from the subject.
    Type: Application
    Filed: July 18, 2018
    Publication date: July 16, 2020
    Inventors: Robert KITCHEN, Michael VALENTINO, Johan SKOG, Vasisht TADIGOTLA, Dalin CHAN, Sudipto CHAKRABORTTY, James HURLEY
  • Publication number: 20200199675
    Abstract: The invention relates generally to the use of microvesicle biomarkers such as nucleic acids, including nucleic acid signatures, and/or proteins for assessing a kidney transplant rejection in a patient. The invention further relates to assessing, and/or to monitoring kidney transplant rejection in patients who have received a renal transplant.
    Type: Application
    Filed: May 16, 2018
    Publication date: June 25, 2020
    Inventors: James HURLEY, Christine COTICCHIA, Robert KITCHEN, Vasisht TADIGOTLA, Johan Karl Olov SKOG, Jamil AZZI
  • Publication number: 20190321708
    Abstract: A golf club that is used to practice a golf swing. Specifically, the golf club includes a handle and a head coupled to the handle. The head is formed from a first portion and a second portion that are coupled together. The first portion may be formed of a rigid material and the second portion may be formed of a resilient material. The second portion may comprise bristles or some other soft, pliable, compressible material that will not damage a surface upon contact during swinging the golf club. The golf club head preferably has the same shape as a traditional golf club head of the same type. However, the second portion forms the sole of the head, thereby eliminating the potential for damage to a floor surface during swinging of the golf club.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 24, 2019
    Inventor: James Hurley
  • Publication number: 20190222628
    Abstract: A method and system for sharing a user interface of a first device with a second device and enabling a user of the second device to interact with the user interface via gestures received by the second device. The first device (e.g., a smartphone) can host an application and generate a graphical user interface, which it transmits to the second device (e.g., a tablet computer) for display by the second device. The second device can receive input from a user, such as a touch input via a touchscreen of the second device, and transmit a representation of the input to the first device for providing input to the application hosted by the first device.
    Type: Application
    Filed: November 12, 2018
    Publication date: July 18, 2019
    Inventors: Anthony Kelani, David Gonen, James Hurley, Matt Van Veenendaal
  • Publication number: 20190093172
    Abstract: The present invention relates generally to the field of biomarker analysis, particularly determining gene expression signatures from biological samples, including plasma samples.
    Type: Application
    Filed: April 17, 2017
    Publication date: March 28, 2019
    Applicant: Exosome Diagnostics, Inc.
    Inventors: Johan Karl Olov SKOG, Mikkel NOERHOLM, James HURLEY, Elena CASTELLANOS-RIZALDOS, Kay BRINKMAN