Patents by Inventor James Ihle

James Ihle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Jak kinases and regulation of cytokine signal transduction
    Patent number: 6969760
    Abstract: The invention relates generally to the Jak family of kinases. This includes the DNA and amino acid sequences for Jak 3 kinases. Additionally, the invention concerns expression vectors comprising DNA sequences encoding a Jak 3 kinase and host cell containing such expression vectors.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: November 29, 2005
    Assignee: St. Jude Children's Research Hospital
    Inventors: James Ihle, Bruce A. Witthuhn, Frederick W. Quelle, Ollie Silvennoinen
  • JAK KINASES AND REGULATION OF CYTOKINE SIGNAL TRANSDUCTION
    Publication number: 20040205835
    Abstract: Provided are methods for regulating the cellular response to cytokines by inhibiting or enhancing of at least one Jak kinase activity which mediates the response; assays for identifying inhibitors of Jak kinase activity or cytokine-induced Jak kinase activation useful in the methods of the invention are also provided; antibodies raised against peptide fragments of at least one epitope specific for a Jak kinase without interfering with kinase activity; polypeptides for Jak kinases; and nucleic acid encoding therefor.
    Type: Application
    Filed: September 17, 1999
    Publication date: October 14, 2004
    Inventors: JAMES IHLE, BRUCE A. WITTHUHN, FREDERICK W. QUELLE, OLLIE SILVENNOINEN
  • Jak kinases and regulation of cytokine signal transduction
    Patent number: 6210654
    Abstract: Provided are methods for regulating the cellular response to cytokines by inhibiting or enhancing of at least one Jak kinase activity which mediates the response; assays for identifying inhibitors of Jak kinase activity or cytokine-induced Jak kinase activation useful in the methods of the invention are also provided; antibodies raised against peptide fragments of at least one epitope specific for a Jak kinase without interfering with kinase activity; polypeptides for Jak kinases; and nucleic acid encoding therefor.
    Type: Grant
    Filed: October 8, 1997
    Date of Patent: April 3, 2001
    Assignee: St. Jude Children's Hospital
    Inventors: James Ihle, Bruce A. Witthuhn, Frederick W. Quelle, Ollie Silvennoinen
  • Jak kinases and regulations of cytokine signal transduction
    Patent number: 6136595
    Abstract: The invention relates generally to the Jak family of kinases. This includes the DNA and amino acid sequences for Jak 3 kinases. Additionally, the invention concerns expression vectors comprising DNA sequences encoding a Jak 3 kinase and host cell containing such expression vectors.
    Type: Grant
    Filed: June 18, 1996
    Date of Patent: October 24, 2000
    Assignee: St. Jude Children's Research Hospital
    Inventors: James Ihle, Bruce A. Witthuhn, Ollie Silvennoinen