Patents by Inventor James J. Crawford
James J. Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11045903Abstract: A device for distributing gas near a weld location includes a cap, a funnel, an inlet, and an aperture. The cap includes a sidewall and an annular lip, and defines a reservoir between the sidewall and the annular lip. The annular lip includes a proximal-most edge. The cap defines an opening, and defines a longitudinal axis. The funnel is disposed adjacent a distal end of the cap. The inlet is disposed in mechanical cooperation with the cap. The aperture is disposed through the sidewall of the cap and is in fluid communication with the inlet. The aperture is disposed distally of the proximal-most edge of the annular lip. Gas is configured to flow through the inlet, through the aperture and into the reservoir. The reservoir is configured to allow the gas to uniformly overflow the proximal-most edge of the annular lip and flow distally through the opening defined by the cap.Type: GrantFiled: November 27, 2018Date of Patent: June 29, 2021Assignee: COVIDIEN LPInventors: Curtis S. German, James J. Crawford, Michael T. Pike
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Patent number: 11008312Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, n, p, q A, B, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.Type: GrantFiled: April 30, 2019Date of Patent: May 18, 2021Assignee: Genentech, Inc.Inventors: Sarah M. Bronner, James J. Crawford, Andrew Cridland, Patrick Cyr, Benjamin Fauber, Emanuela Gancia, Alberto Gobbi, Christopher Hurley, Jonathan Killen, Wendy Lee, Olivier Rene, Monique Bodil Van Niel, Stuart Ward, Paul Winship, Jason Zbieg
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Publication number: 20200179036Abstract: An electrosurgical instrument includes first and second jaw members each including an outer jaw housing, a tissue-treating plate, and a longitudinally-extending knife channel. The electrosurgical instrument also includes a knife actuator and a knife assembly operably coupled to the knife actuator. The knife assembly includes an elongated tube defining a longitudinal lumen and an elongated shaft having a proximal portion coupled to the knife actuator and a distal portion configured to be received through the longitudinal lumen. The distal portion of the elongated shaft includes an enlarged distal end portion configured to prevent movement of the elongated shaft relative to the elongated tube. The knife assembly also includes a knife blade having a pair of opposing lateral sides and a sharpened distal end configured to cut tissue. The elongated tube is configured to be coupled to one of the pair of opposing lateral sides of the knife blade.Type: ApplicationFiled: December 4, 2019Publication date: June 11, 2020Inventors: Allen E. Honegger, James J. Crawford
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Publication number: 20200181154Abstract: Pyrazole carboxamide compounds of Formula I are provided, with various substituents, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.Type: ApplicationFiled: February 12, 2020Publication date: June 11, 2020Applicant: Genentech, Inc.Inventors: Roland J. BILLEDEAU, James J. CRAWFORD, Saul JAIME-FIGUEROA, Wendy LEE, Francisco Javier LOPEZ-TAPIA, Sung-Sau SO
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Publication number: 20190263794Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, n, p, q A, B, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.Type: ApplicationFiled: April 30, 2019Publication date: August 29, 2019Applicant: Genentech, Inc.Inventors: Sarah M. Bronner, James J. Crawford, Andrew Cridland, Patrick Cyr, Benjamin Fauber, Emanuela Gancia, Alberto Gobbi, Christopher Hurley, Jonathan Killen, Wendy Lee, Olivier Rene, Monique Bodil Van Niel, Stuart Ward, Paul Winship, Jason Zbieg
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Publication number: 20190194209Abstract: Pyrazole carboxamide compounds of Formula I are provided, with various substituents, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.Type: ApplicationFiled: February 28, 2019Publication date: June 27, 2019Applicant: Genentech, Inc.Inventors: Roland J. BILLEDEAU, James J. CRAWFORD, Saul JAIME-FIGUEROA, Wendy LEE, Francisco Javier LOPEZ-TAPIA, Sung-Sau SO
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Publication number: 20190168338Abstract: A device for distributing gas near a weld location includes a cap, a funnel, an inlet, and an aperture. The cap includes a sidewall and an annular lip, and defines a reservoir between the sidewall and the annular lip. The annular lip includes a proximal-most edge. The cap defines an opening, and defines a longitudinal axis. The funnel is disposed adjacent a distal end of the cap. The inlet is disposed in mechanical cooperation with the cap. The aperture is disposed through the sidewall of the cap and is in fluid communication with the inlet. The aperture is disposed distally of the proximal-most edge of the annular lip. Gas is configured to flow through the inlet, through the aperture and into the reservoir. The reservoir is configured to allow the gas to uniformly overflow the proximal-most edge of the annular lip and flow distally through the opening defined by the cap.Type: ApplicationFiled: November 27, 2018Publication date: June 6, 2019Inventors: CURTIS S. GERMAN, JAMES J. CRAWFORD, MICHAEL T. PIKE
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Patent number: 10280144Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, A, X, Y, Z, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.Type: GrantFiled: November 1, 2017Date of Patent: May 7, 2019Assignee: Genentech, Inc.Inventors: Benjamin Fauber, James J. Crawford, Sarah M. Bronner, Monique Bodil van Niel, Andrew Cridland, Emanuela Gancia, Christopher Hurley, Jonathan Killen, Stuart Ward
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Publication number: 20180072683Abstract: Compounds of formula I: or pharmaceutical salts thereof, wherein m, A, X, Y, Z, R1, R2, R3, R4 and R5are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.Type: ApplicationFiled: November 1, 2017Publication date: March 15, 2018Applicant: Genentech, Inc.Inventors: Benjamin Fauber, James J. Crawford, Sarah M. Bronner, Monique Bodil van Niel, Andrew Cridland, Emanuela Gancia, Christopher Hurley, Jonathan Killen, Stuart Ward
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Publication number: 20180057500Abstract: Pyrazole carboxamide compounds of Formula I are provided, with various substituents, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.Type: ApplicationFiled: August 29, 2017Publication date: March 1, 2018Applicant: Genentech, Inc.Inventors: Roland J BILLEDEAU, James J. CRAWFORD, Saul JAIME-FIGUEROA, Wendy LEE, Francisco Javier LOPEZ-TAPIA, Sung-Sau SO
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Publication number: 20150031674Abstract: Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.Type: ApplicationFiled: July 25, 2014Publication date: January 29, 2015Applicant: GENENTECH, INC.Inventors: Joachim Rudolph, Lewis J. Gazzard, James J. Crawford, Chudi Ndubaku, Joy Drobnick, Wendy Lee
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Publication number: 20140323477Abstract: Compounds having the formula I, or a pharmaceutically acceptable salt thereof, wherein R1, R2, X1, X2, and Ar are as defined herein, are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders using such compounds.Type: ApplicationFiled: April 30, 2014Publication date: October 30, 2014Applicant: GENENTECH, INC.Inventors: James J. CRAWFORD, Wendy LEE, Joachim RUDOLPH
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Patent number: 8754077Abstract: 8-Fluorophthalazin-1(2h)-one compounds of Formula I where one or two of X1, X2, and X3 are N, are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.Type: GrantFiled: January 13, 2014Date of Patent: June 17, 2014Assignee: F. Hoffmann-La Roche AGInventors: James J. Crawford, Daniel F. Ortwine, BinQing Wei, Wendy B. Young
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Patent number: 8646164Abstract: An automated device facilitates the assembly a surgical instrument that includes a knife with a high aspect ratio. The automated device includes a fixture for restraining a subassembly of the surgical instrument that includes the knife. A blade grip on the device is movable relative to the fixture, and is configured to urge the knife into a restrained position in the subassembly suitable for the subsequent assembly of an additional instrument component. A grip actuator is provided to move the blade grip.Type: GrantFiled: March 30, 2009Date of Patent: February 11, 2014Assignee: Covidien LPInventors: James S. Cunningham, James J. Crawford, Paul Guerra
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Patent number: 8484833Abstract: An automated device facilitates the assembly a surgical instrument that includes a knife with a high aspect ratio. The automated device includes a fixture for restraining a subassembly of the surgical instrument that includes the knife. A blade grip on the device is movable relative to the fixture, and is configured to urge the knife into a restrained position in the subassembly suitable for the subsequent assembly of an additional instrument component. A grip actuator is provided to move the blade grip.Type: GrantFiled: September 10, 2009Date of Patent: July 16, 2013Assignee: Covidien LPInventors: James S. Cunningham, James J. Crawford, Paul Guerra
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Publication number: 20090320268Abstract: An automated device facilitates the assembly a surgical instrument that includes a knife with a high aspect ratio. The automated device includes a fixture for restraining a subassembly of the surgical instrument that includes the knife. A blade grip on the device is movable relative to the fixture, and is configured to urge the knife into a restrained position in the subassembly suitable for the subsequent assembly of an additional instrument component. A grip actuator is provided to move the blade grip.Type: ApplicationFiled: September 10, 2009Publication date: December 31, 2009Inventors: James S. Cunningham, James J. Crawford, Paul Guerra
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Publication number: 20090248052Abstract: An automated device facilitates the assembly a surgical instrument that includes a knife with a high aspect ratio. The automated device includes a fixture for restraining a subassembly of the surgical instrument that includes the knife. A blade grip on the device is movable relative to the fixture, and is configured to urge the knife into a restrained position in the subassembly suitable for the subsequent assembly of an additional instrument component. A grip actuator is provided to move the blade grip.Type: ApplicationFiled: March 30, 2009Publication date: October 1, 2009Inventors: James S. Cunningham, James J. Crawford, Paul Guerra
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Patent number: 5994844Abstract: A video lighthead mountable to a video camera and having a dimmer control that varies the intensity of the light output from the lighthead using pulse width modulation techniques. A photo sensor measures the intensity of light reflected from a subject in front of the lighthead. The intensity of light output from the lighthead is adjusted by control circuitry in response to changes in measured reflected light intensity to maintain a constant level of illumination. The adjustment is carried out by modifying the duty cycle of a pulse width modulation circuit. The duty cycle adjustment of the pulse width modulation is also used to compensate for supply voltage variations in order to maintain constant light output.Type: GrantFiled: December 12, 1997Date of Patent: November 30, 1999Assignee: Frezzolini ELectronics, Inc.Inventors: James J. Crawford, Kevin J. Crawford
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Patent number: 5721756Abstract: A digital data receiver includes tunable analog components having variable parameters that are responsive to the bit error rate (BER) of the decoded digital data. The analog components include a quadrature generator having a tunable phase shifter, an analog filter having a tunable bandwidth, a tunable magnitude equalizer circuit, a tunable group delay equalizer circuit, and an amplifier having an adjustable gain. The tunable components are controlled by tuning control signals that incorporate digitally-produced fine tuning signals. The digital tuning signals are altered in accordance with realtime changes in the BER.Type: GrantFiled: March 26, 1996Date of Patent: February 24, 1998Assignee: Sicom, Inc.Inventors: John Michael Liebetreu, Eric Martin Brombaugh, Ronald Duane McCallister, James J. Crawford
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Patent number: D486259Type: GrantFiled: March 28, 2003Date of Patent: February 3, 2004Assignee: Frezzolini Electronics Inc.Inventors: James J. Crawford, Kevin Crawford