Abstract: The temperature of a patient is a significant predictor of death in heart failure patients. Temperature provides a window into the physiology of the patient's underlying condition and may be used as an early marker for CHF exacerbations. The patient's temperature is taken to form a time series of temperature values. In accordance with some embodiments, the time series of temperature values is converted to the frequency domain by, for example, a discrete Fourier Transform. The frequency domain representation then is analyzed for a marker indicative of the worsening condition of the patient. In accordance with other embodiments, the patient's time series of temperature values is analyzed for a marker using, for example, Cosinor analysis. In yet other embodiments, both the time and frequency domain temperature data is analyzed for markers of the patient's worsening medical condition.

Abstract: An electrical circuit is presented that includes an anode conductor formed from a first wire and a cathode conductor formed from a second wire. The first wire and the second wire each comprised of a predetermined diameter. At least a portion of the predetermined diameter of the wires is compressed or extruded to provide an increased surface area. The conductors are disposed about an electrolyte material of an energy generating device, e.g., a fuel cell. The increased surface area of the leads increases a total collected energy of the fuel cell without increasing the conductor mass or tensile strength such that weight and other characteristics of the fuel cell are not adversely impacted as compared to conventional fuel cell arrangements.

Abstract: An electrical circuit is presented that includes an anode conductor formed from a first wire lead and a cathode conductor formed from a second wire lead. The first wire lead and the second wire lead are each comprised of wire having a predetermined diameter. At least a portion of the predetermined diameter of at least one of the first and the second wire leads is compressed to provide an increased surface area. In one embodiment, the anode and the cathode conductors are disposed about an electrolyte material of an energy generating device, e.g., a fuel cell. The increased surface area of the at least one first and the second leads increases a total collected energy of the fuel cell without increasing the conductor mass or tensile strength such that weight and other characteristics of the fuel cell are not adversely impacted as compared to conventional fuel cell arrangements.

Abstract: The temperature of a patient is a significant predictor of death in heart failure patients. Temperature provides a window into the physiology of the patient's underlying condition and may be used as an early marker for CHF exacerbations. The patient's temperature is taken to form a time series of temperature values. In accordance with some embodiments, the time series of temperature values is converted to the frequency domain by, for example, a discrete Fourier Transform. The frequency domain representation then is analyzed for a marker indicative of the worsening condition of the patient. In accordance with other embodiments, the patient's time series of temperature values is analyzed for a marker using, for example, Cosinor analysis. In yet other embodiments, both the time and frequency domain temperature data is analyzed for markers of the patient's worsening medical condition.