Patents by Inventor James J. Harter

James J. Harter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Highly efficient production and isolation of viral particles utilizing tentacle anion exchange
    Patent number: 6080571
    Abstract: This invention is directed to a continuous process for producing viral particles comprising providing in a perfused growth medium a population of viable virally infected non-lytic cells, and removing medium containing said cells at a rate to maintain the steady-state log-phase growth of cells remaining in said perfused growth medium. The invention is also directed to a process for purifying retroviral particles comprising passing a solution comprising the retroviral particles and contaminants through an anion exchange resin, and eluting the retroviral particles from the resin.
    Type: Grant
    Filed: April 15, 1997
    Date of Patent: June 27, 2000
    Assignee: The Immune Response Corporation
    Inventors: Christopher P. Prior, David M. Weber, Richard S. Gore, James J. Harter
  • Production and purification of retroviral particles using tentacle anion exchange
    Patent number: 5661023
    Abstract: This invention is directed to a continuous process for producing viral particles by providing in a perfused growth medium a population of viable virally infected non-lytic cells, and removing medium containing said cells at a rate to maintain the steady-state log-phase growth of cells remaining in the perfused growth medium. The invention is also directed to a process for purifying retroviral particles by passing a solution comprising the retroviral particles and contaminants through an anion exchange resin, and eluting the retroviral particles from the resin. The preferred exchange resin is a tentacle anion exchange resin.
    Type: Grant
    Filed: March 11, 1996
    Date of Patent: August 26, 1997
    Assignee: The Immune Response Corporation
    Inventors: Michael E. Hrinda, Christopher P. Prior, Jonathan J. Mitschelen, Thomas W. Irish, David M. Weber, Richard S. Gore, James J. Harter, Pierre M. Bay, George C. Tarr