Abstract: A secondary battery is provided for cycling between a charged and a discharged state, the secondary battery including a battery enclosure, an electrode assembly, carrier ions, a non-aqueous liquid electrolyte within the battery enclosure, and a set of electrode constraints. The set of electrode constraints includes a primary constraint system having first and second primary growth constraints and at least one primary connecting member, the first and second primary growth constraints separated from each other in the longitudinal direction, wherein the primary constraint array restrains growth of the electrode assembly in the longitudinal direction such that any increase in the Feret diameter of the electrode assembly in the longitudinal direction over 20 consecutive cycles of the secondary battery is less than 20%.

Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A surgical stringer includes a pair of bases, each of the pair of bases having a flat bottom surface, the pair of bases being rotatable with respect to one another, and a pair of poles, each of the pair of poles being coupled to a one of the pair of bases and extending orthogonally thereto, the distance between the pair of poles being variable.

Abstract: A surgical stringer includes a pair of bases, each of the pair of bases having a flat bottom surface, a pivot coupling the pair of bases together, the pair of bases being rotatable with respect to one another, and a pair of poles, each of the pair of poles being coupled to a one of the pair of bases and extending orthogonally thereto, the distance between the pair of poles being variable.

Abstract: A fenestration system includes a frame defining a sealing slot; a pane assembly assembled with the frame, the pane assembly defining an edge; a gap defined between the frame and the edge; and a fin seal defining a connector portion and a fin portion extending from the connector portion, the connector portion engaging the sealing slot, the fin portion extending across the gap and abutting the edge, the fin portion tapering in thickness between the connector portion and the edge.

Abstract: A speculum includes an insulating sleeve having a body, the body having a first side edge, a second side edge, a front edge and a back edge, and a metallic sheet having a first end, a second end, a front end and a back end, the back end being tailored to match a back edge of the sleeve, the metallic sheet being covered by the body of the sleeve.

Abstract: A speculum includes an insulating sleeve having a body, the body having a first side edge, a second side edge, a front edge and a back edge, and a metallic sheet having a first end, a second end, a front end and a back end, the back end being tailored to match a back edge of the sleeve, the metallic sheet being covered by the body of the sleeve.

Abstract: Example aspects of a fenestration system and a method for insulating a fenestration system are disclosed. The fenestration system can comprise a frame comprising a first frame side, the first frame side comprising an interior wall, the interior wall defining a sealing slot; and a seal comprising a connector portion engaging the sealing slot and an extension portion extending from the connector portion.

Abstract: A surgical stringer includes a pair of bases, each of the pair of bases having a flat bottom surface, a pivot coupling the pair of bases together, the pair of bases being rotatable with respect to one another, and a pair of poles, each of the pair of poles being coupled to a one of the pair of bases and extending orthogonally thereto, the distance between the pair of poles being variable.

Abstract: A speculum includes an insulating sleeve having a body, the body having a first side edge, a second side edge, a front edge and a back edge, and a metallic sheet having a first end, a second end, a front end and a back end, the back end being tailored to match a back edge of the sleeve, the metallic sheet being covered by the body of the sleeve.

Abstract: A simplified and improved pistonless cylinder based on an Aramid fiber reinforced elastomer tubular which is highly stiff in radial direction against radial expansion and elastic in axial extension, so as to form a completely sealed and extendable pressure chamber and to be able to perform as well as, or better than, most of the conventional hydraulic cylinders in terms of load bearing capacities, maximum stroke distances and service durability. This simplified cylinder employs no piston, piston rod, sealing seals or oil based hydraulic fluid, and utilizes non-metal materials to construct the majority of the parts for its extendable pressure chamber; therefore, this new cylinder can achieve significant weight and fabrication cost reduction. In addition, this new pistonless cylinder uses ordinary liquids, e.g., fresh water or seawater, as its hydraulic fluid, and can work directly as a hydraulic or pneumatic cylinder interchangeably without a need for much, if any, modification.

Abstract: A simplified and improved pistonless cylinder based on an Aramid fiber reinforced elastomer tubular which is highly stiff in radial direction against radial expansion and elastic in axial extension, so as to form a completely sealed and extendable pressure chamber and to be able to perform as well as, or better than, most of the conventional hydraulic cylinders in terms of load bearing capacities, maximum stroke distances and service durability. This simplified cylinder employs no piston, piston rod, sealing seals or oil based hydraulic fluid, and utilizes non-metal materials to construct the majority of the parts for its extendable pressure chamber; therefore, this new cylinder can achieve significant weight and fabrication cost reduction. In addition, this new pistonless cylinder uses ordinary liquids, e.g., fresh water or seawater, as its hydraulic fluid, and can work directly as a hydraulic or pneumatic cylinder interchangeably without a need for much, if any, modification.

Abstract: This document provides methods and materials involved in treating bladder cancer. This document also provides methods and materials involved in identifying bladder cancer patients likely or unlikely to respond to treatment (e.g., BCG therapy).

Abstract: This invention discloses a new type of force bearing cylinder which does not use any piston and its related parts for pushing/pulling its stroke. The pistonless cylinder uses ordinary liquids, e.g., fresh water or seawater, as its hydraulic fluid. The pistonless cylinder can work as a hydraulic or pneumatic cylinder interchangeably without a need for any modification, and is basically maintenance free during its service life. As one example of its applications, the disclosed pistonless cylinder can be used for deepwater pile grippers in offshore platform installation.

Abstract: This document provides methods and materials involved in treating bladder cancer. This document also provides methods and materials involved in identifying bladder cancer patients likely or unlikely to respond to treatment (e.g., BCG therapy).

Abstract: This documents provided methods and materials involved in treating bladder cancer. This document also provides methods and materials involved in identifying bladder cancer patients likely or unlikely to respond to treatment (e.g., BCG therapy).

Abstract: This documents provided methods and materials involved in treating bladder cancer. This document also provides methods and materials involved in identifying bladder cancer patients likely or unlikely to respond to treatment (e.g., BCG therapy).

Abstract: Gene knock-in mice having a targeted insertion of the human diphtheria toxin receptor within the eosinophil peroxidase locus are described. Administering diphtheria toxin to such animals results in the loss of eosinophils in the animal. Accordingly, the knock-in mice and nucleic acid constructs featured in the document can be used to generate eosinophil-deficient transgenic animals that are useful for studying pathologies and treatments relating to tissues and organ systems that typically contain eosinophils.

Abstract: Methods for the treatment of sepsis are disclosed.

Abstract: The present invention provides a container for dispensing individual paper products that includes a housing having side walls defining an interior area for receiving a plurality of paper products, wherein one of the side walls defines a slot. The housing further includes a means for urging paper products having a first portion external to the housing and a second portion extending through the slot into the interior area of the housing. The container may be included in a system for dispensing individual paper products that further includes a cartridge containing paper products within the container. The cartridge defines a dispensing opening and a second slot wherein the second portion of the means for urging paper products extends through the second slot into the interior area of the cartridge to contact the paper products and urge the paper products toward the dispensing opening.