Patents by Inventor James J. Mulé

James J. Mulé has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CREATING BIOENGINEERED LYMPH NODES
    Publication number: 20120244181
    Abstract: The invention provides compositions and methods of treating various conditions, including tumors, with compositions comprising dendritic cells expressing exogenous chemokines.
    Type: Application
    Filed: November 16, 2010
    Publication date: September 27, 2012
    Inventor: James J. Mule
  • CHEMOKINE GENE-MODIFIED CELLS FOR CANCER IMMUNOTHERAPY
    Publication number: 20110059137
    Abstract: Described herein are methods of cancer immunotherapy, particularly compositions comprising genetically-modified cells that express macrophage colony stimulating factor (GM-CSF), CD40 ligand (CD40L), and chemokine C—C motif ligand 21 (CCL21), wherein the population of cells comprises bystander cells and target cancer cells, and methods of making these compositions and treating cancer using these compositions.
    Type: Application
    Filed: March 19, 2009
    Publication date: March 10, 2011
    Applicants: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTUTE, INC, UNIVERSITY OF SOUTH FLORIDA
    Inventors: Scott Joseph Antonia, James J. Mule
  • ENHANCED DENDRITIC CELLS FOR CANCER IMMUNOTHERAPY
    Publication number: 20110059054
    Abstract: Described herein are methods of cancer immunotherapy, particularly methods of preparing a population of enhanced dendritic cells and methods of treating cancer using the enhanced dendritic cells.
    Type: Application
    Filed: March 10, 2009
    Publication date: March 10, 2011
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: James J. Mule, Shari A. Pilon-Thomas, Norimasa Matsushita, Annabelle Grolleau-Julius