Abstract: A medical device that includes a handle including a plurality of actuators. The handle defines a longitudinal axis extending through a distal end of the handle. The device includes a shaft extending from the handle and an end effector at a distal end of the shaft. A first actuator of the plurality of actuators is configured to actuate the end effector in response to translation of the first actuator relative to the handle along an axis parallel to the longitudinal axis. A second actuator of the plurality of actuators is configured to deflect the end effector relative to the shaft in response to pivoting the second actuator about an axis transverse to the longitudinal axis. A third actuator of the plurality of actuators is configured to rotate the end effector relative to the shaft in response to rotation of the third actuator relative to the handle about the longitudinal axis.

Abstract: A method for coupling a first medical device component to a second medical device component comprising altering the first medical device component from a natural state to an altered state, by reducing a cross-sectional dimension of the first medical device, fitting a first portion of the first medical device component in the altered state into a first opening of the second medical device component, wherein the first medical device component includes second portions not within the first opening of the second medical device component, and allowing the second portions of the first medical device component to revert back to the natural state.

Abstract: A method for coupling a first medical device component to a second medical device component includes altering the first medical device component from a natural state to an altered state, by reducing a cross-sectional dimension of the first medical device. The method further includes fitting a first portion of the first medical device component in the altered state into a first opening of the second medical device component. The first medical device component includes second portions not within the first opening of the second medical device component. The method further includes allowing the second portions of the first medical device component to revert back to the natural state.

Abstract: A closure device includes a first ring structure having a first distal portion and a first medial portion and a second ring structure having a second distal portion and a second medial portion. The first and second distal portions are movable between an open position, where the first and second distal portions form an angle relative to one another for receiving target tissue therebetween, and a closed position, where the first and second distal portions are drawn toward one another for gripping the target tissue. The device also includes an anvil about which the first and second medial portions are formed. Either one of proximal motion of the anvil relative to the first and second rings or proximal motion of the medial portions relative to the anvil causes the first and second distal portions to move into either one of the open position or the closed position.

Abstract: The present disclosure relates to compression clips, and more specifically, to compression clips delivered to a target site through an endoscope for use in tissue resection, for example, within the gastrointestinal tract. In examples, clips are configured to be actuatable in response to a compressive force to transition between an open configuration and a closed configuration. In an embodiment, a tissue clipping device may include a first member with a plurality of arms. Each of the arms may extend from a first end to a second end, and the first end of each arm may be received within the first member. The arms may be movable between the open configuration and the closed configuration. A second member may be slidably disposed with respect to the first member.

Abstract: A closure device includes a first ring structure having a first distal portion and a first medial portion and a second ring structure having a second distal portion and a second medial portion. The first and second distal portions are movable between an open position, where the first and second distal portions form an angle relative to one another for receiving target tissue therebetween, and a closed position, where the first and second distal portions are drawn toward one another for gripping the target tissue. The device also includes an anvil about which the first and second medial portions are formed. Either one of proximal motion of the anvil relative to the first and second rings or proximal motion of the medial portions relative to the anvil causes the first and second distal portions to move into either one of the open position or the closed position.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to endoscopic medical devices with distally actuated axial displacement configured to impart in-plane or rotational ultrasonic reciprocation to an end effector.

Abstract: The present disclosure relates to compression clips, and more specifically, to compression clips delivered to a target site through an endoscope for use in tissue resection, for example, within the gastrointestinal tract. In examples, clips are configured to be actuatable in response to a compressive force to transition between an open configuration and a closed configuration. In an embodiment, a tissue clipping device may include a first member with a plurality of arms. Each of the arms may extend from a first end to a second end, and the first end of each arm may be received within the first member. The arms may be movable between the open configuration and the closed configuration. A second member may be slidably disposed with respect to the first member.

Abstract: The disclosure relates generally to devices and methods for treating a tissue defect, for example, by suturing. In some embodiments, a suturing device may include an elongate member having a working channel, a suture channel, and a suture arm extending from the elongate member. The suturing device may further include a needle passer located within the working channel, the needle passer operable to deliver a needle between the elongate member and a distal end of the suture arm for suturing a target tissue, and a suture extending through the suture channel, wherein the suture is coupled to the needle. The suturing device may further include a plurality of imaging devices, wherein a first imaging device is positioned along a distal face of the elongate member, and wherein a second imaging device is positioned along the suture arm.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to endoscopic medical devices with distally actuated axial displacement configured to impart in-plane or rotational ultrasonic reciprocation to an end effector.

Abstract: A medical device may comprise a handle portion; an insertion portion having a proximal end portion at the handle portion, wherein the insertion portion includes a lumen therein and a distal end having a distal opening in communication with the lumen; and a member disposed within the lumen, the member having a distal end portion with an imaging device. The member may be configured to transition between a first configuration and a second configuration. In the first configuration, the imaging device may face distally, and, in the second configuration, the imaging device may face proximally. Extending the distal end portion of the member distally past the distal opening may cause the member to transition from the first configuration to the second configuration.

Abstract: A valve for use in an endoscope may comprise a proximal valve stem member having a first lumen extending from a proximal opening at a proximalmost end of the proximal valve stem member to a distal opening at a distalmost end of the proximal valve stem member. A distal valve stem member may have a second lumen with a proximal opening at a proximalmost end of the distal valve stem member. The proximalmost end of distal valve stem member may be received within the distal opening of the first lumen. The distal valve stem may be movable relative to the proximal valve stem.

Abstract: The present disclosure relates generally to devices and methods for treating a tissue defect, for example, by suturing. In some embodiments, a suturing device may include an elongate member having a working channel, a suture channel, and a suture arm extending from the elongate member. The suturing device may further include a needle passer located within the working channel, the needle passer operable to deliver a needle between the elongate member and a distal end of the suture arm for suturing a target tissue, and a suture extending through the suture channel, wherein the suture is coupled to the needle. The suturing device may further include a plurality of imaging devices, wherein a first imaging device is positioned along a distal face of the elongate member, and wherein a second imaging device is positioned along the suture arm.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to single-use endoscopic medical devices with integrated and purpose-built functionality.

Abstract: A medical device may comprise a handle portion; an insertion portion having a proximal end portion at the handle portion, wherein the insertion portion includes a lumen therein and a distal end having a distal opening in communication with the lumen; and a member disposed within the lumen, the member having a distal end portion with an imaging device. The member may be configured to transition between a first configuration and a second configuration. In the first configuration, the imaging device may face distally, and, in the second configuration, the imaging device may face proximally. Extending the distal end portion of the member distally past the distal opening may cause the member to transition from the first configuration to the second configuration.

Abstract: A valve for use in an endoscope may comprise a proximal valve stem member having a first lumen extending from a proximal opening at a proximalmost end of the proximal valve stem member to a distal opening at a distalmost end of the proximal valve stem member. A distal valve stem member may have a second lumen with a proximal opening at a proximalmost end of the distal valve stem member. The proximalmost end of distal valve stem member may be received within the distal opening of the first lumen. The distal valve stem may be movable relative to the proximal valve stem.

Abstract: This disclosure relates to the field of luminal surgery. Specifically, the present disclosure relates to medical devices that expand within a body lumen for accessing a target tissue. In an aspect, an expandable device for a body lumen may include a filament comprising a proximal end, a distal end, and a length. The device may include a plurality of segments. Each segment may comprise a middle portion comprising a longitudinal axis extending axially therethrough, a projection portion extending from an end of the middle portion along the longitudinal axis, and a receptive portion extending from an opposing end of the middle portion away from the longitudinal axis, the receptive portion configured to receive the projection portion of an adjacent one of the plurality of segments. An aperture may be disposed through the projection portion, the middle portion, and the receptive portion.

Abstract: Medical stent designs are disclosed. An example stent includes a tubular scaffold having a proximal end and a distal end. The tubular scaffold includes a first filament extending between the proximal end and the distal end, the first filament including a first biodegradable region positioned adjacent to a second biodegradable region. Further, the first biodegradable region includes a first biodegradable material, the first biodegradable material having a first rate of degradation. The second biodegradable region includes a second biodegradable material, the second biodegradable material having a second rate of degradation, wherein the first rate of degradation is different from the second rate of degradation.

Abstract: A medical device having multiple degrees of freedom independent of each other. The medical device includes a handle, an end effector, and a tubular section extending between the handle and the end effector. The end effector is configured to be rotated about a first axis extending through the tubular section without rotating the tubular section. And, the tubular section is configured to be rotated about the first axis with the end effector.

Abstract: A medical device system includes an insertion device and a medical device. The insertion device includes an insertion device handle, including a port on a handle body. The insertion device also includes an insertion device shaft extending from the insertion device handle. The insertion device shaft includes a working channel connected to the port. The medical device includes a medical device handle, including a movable handle portion and a stationary handle portion. The movable handle portion includes a ball portion movably positioned within a cavity in the stationary handle portion. The medical device also includes a medical device shaft. The medical device shaft is configured to be delivered through the port in the insertion device handle and through the working channel in the insertion device shaft. Movement of the movable handle portion relative to the stationary handle portion controls movement of a distal portion of the medical device shaft.