Patents by Inventor James Jaquith

James Jaquith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IAP bir domain binding compounds
    Publication number: 20080069812
    Abstract: Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I or II or a salt thereof, in which R1, R2, R3, R100, R200, R300, A, A1, BG, Q and Q1 are substituents described herein. Also disclosed is the use of compounds of Formula I and II to treat proliferative disorders such as cancer.
    Type: Application
    Filed: March 16, 2007
    Publication date: March 20, 2008
    Applicant: AEGERA THERAPEUTICS, INC.
    Inventors: Alain Boudreault, James Jaquith
  • IAP BIR domain binding compounds
    Publication number: 20080014207
    Abstract: Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I: or a salt thereof, in which R1, R2, R100, R200, A, A1, B, B1, BG, n, Q and Q1 are substituents described. Also disclosed is the use of compounds of Formula 1 to treat proliferative disorders.
    Type: Application
    Filed: December 1, 2006
    Publication date: January 17, 2008
    Applicant: AEGERA THERAPEUTICS, INC.
    Inventors: Alain Laurent, Kim Hewitt, Stephen Morris, Patrick Bureau, Alain Boudreault, Scott Jarvis, James Jaquith
  • Imidazo[2,1-b]-1,3,4-thiadiazole sulfonamides
    Publication number: 20070265319
    Abstract: This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: May 7, 2007
    Publication date: November 15, 2007
    Applicant: AEGERA THERAPEUTICS, INC.
    Inventors: James Jaquith, Alain Boudreault, Stephen Morris, Jon Durkin, John Gillard, Kimberley Hewitt
  • Imidazo[2,1-b]-1,3,4-thiadiazole sulfonamides
    Publication number: 20070238766
    Abstract: This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: May 7, 2007
    Publication date: October 11, 2007
    Applicant: AEGERA THERAPEUTICS, INC.
    Inventor: James Jaquith
  • Imidazo[2,1-b]-1,3,4-thiadiazole sulfonamides
    Publication number: 20070238768
    Abstract: This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: May 7, 2007
    Publication date: October 11, 2007
    Applicant: AEGERA THERAPEUTICS, INC.
    Inventors: James Jaquith, Alain Boudreault, Stephen Morris, Jon Durkin, John Gillard, Kimberley Hewitt
  • IAP BIR domain binding compounds
    Publication number: 20070219140
    Abstract: Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I: or a salt thereof, in which R1, R2, R100, R200, A, A1, B, B1, BG, n, Q and Q1 are substitutents described. Also disclosed is the use of compounds of Formula 1 to treat proliferative disorders.
    Type: Application
    Filed: December 4, 2006
    Publication date: September 20, 2007
    Applicant: AEGERA THERAPEUTICS, INC.
    Inventors: Alain Laurent, Kim Hewitt, Stephen Morris, Patrick Bureau, Alain Boudreault, Scott Jarvis, James Jaquith
  • Acylated and non-acylated imidazo[2,1-b]-1,3,4,-thiadiazole-2-sulfonamides, and uses thereof
    Publication number: 20070112043
    Abstract: This invention relates to novel compounds of Formula (I): and the use of compounds of Formula (I) in the treatment of neuronal disorders of the central and peripheral nervous systems and for the treatment of proliferative diseases, such as cancer.
    Type: Application
    Filed: June 14, 2004
    Publication date: May 17, 2007
    Inventors: James Jaquith, John Gillard
  • IAP BIR domain binding compounds
    Publication number: 20070093429
    Abstract: Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I: or a salt thereof, in which R1, R2, R100, R200, A, A1, B, B1, BG, n, Q and Q1 are substituents described. Also disclosed is the use of compounds of Formula 1 to treat proliferative disorders.
    Type: Application
    Filed: December 4, 2006
    Publication date: April 26, 2007
    Applicant: AEGERA THERAPEUTICS, INC.
    Inventors: Alain Laurent, Kim Hewitt, Stephen Morris, Patrick Bureau, Alain Boudreault, Scott Jarvis, James Jaquith
  • Imidazo[2,1-b]-1,3,4-thiadiazole sulfonamides
    Publication number: 20070088059
    Abstract: This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: April 6, 2006
    Publication date: April 19, 2007
    Inventors: James Jaquith, Gerald Villeneuve, Alain Boudreault, Stephen Morris, Jon Durkin, John Gillard, Kimberley Hewitt, H. Marsh
  • Imidazo[2,1-b]-1,3,4-thiadiazole sulfonamides
    Publication number: 20070021476
    Abstract: This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: April 5, 2006
    Publication date: January 25, 2007
    Inventors: James Jaquith, Gerald Villeneuve, Alain Boudreault, Stephen Morris, Jon Durkin, John Gillard, Kimberley Hewitt, H. Marsh
  • Imidazo[2,1-b]-1,3,4-thiadiazole sulfonamides
    Publication number: 20070021416
    Abstract: This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: April 6, 2006
    Publication date: January 25, 2007
    Inventors: James Jaquith, Gerald Villeneuve, Alain Boudreault, Stephen Morris, Jon Durkin, John Gillard, Kimberley Hewitt, H. Marsh
  • BIR domain binding compounds
    Publication number: 20060264379
    Abstract: The present invention is directed towards an isomer, an enantiomer, a diastereoisomer, or a tautomer of a pyrrolidine compound represented by Formula I: in which the substituents R1, R1a, R2, R2a, R3, A and Q are defined herein; or a prodrug, or a salt thereof, and which bind to IAP BIR domains.
    Type: Application
    Filed: May 16, 2006
    Publication date: November 23, 2006
    Inventors: Scott Jarvis, Alain Boudreault, Patrick Bureau, James Jaquith, Alain Laurent, Delphine Labit
  • Neuroprotective benzo 1 3 oxathiol 2 ones
    Publication number: 20060234987
    Abstract: This invention relates to benzo[1,3]oxathiol-2-ones, derivatives, and precursors thereof, and their use as neuroprotective agents in the treatment and prevention of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: July 29, 2004
    Publication date: October 19, 2006
    Inventor: James Jaquith
  • Neuroprotective and anti-proliferative compounds
    Publication number: 20060199835
    Abstract: This invention features compounds of formula (I), (II) and (III), which are useful in the treatment of proliferative disorders characterized by loss of growth or cellular differentiation control including, but not limited to, cancer and inflammation. Formulas (I), (II), (III) have functional groups designated as A1, A2, B1, B2, X1—X9 and R1—R8 as defined further.
    Type: Application
    Filed: August 11, 2004
    Publication date: September 7, 2006
    Inventors: James Jaquith, John Gillard, Alain Laurent
  • Imidazo(2,1-b)-1,3,4-thiadiazole sulfoxides and sulfones
    Publication number: 20060135571
    Abstract: This invention relates to novel imidazo[2,1-b]-1,3,4-thiadiazole sulfoxide and sulfone compounds of Formula (I) and the use of compounds of Formula (I) in the treatment of neuronal disorders of the central and peripheral nervous systems and for the treatment of proliferative diseases such as cancer.
    Type: Application
    Filed: June 14, 2004
    Publication date: June 22, 2006
    Inventors: James Jaquith, John Gillard, Patrick Bureau, Scott Jarvis
  • Imidazo [2,1-b]-1,3,4-thiadiazole suflonamides
    Publication number: 20050069492
    Abstract: This invention relates to compounds of Formula (I) and the use of compounds of Formula (I) as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
    Type: Application
    Filed: December 16, 2002
    Publication date: March 31, 2005
    Inventors: James Jaquith, Gerald Villeneuve, Alain Boudreault, Stephen Morris, Jon Durkin, John Gillard, Kimberly Hewitt, H. Marsh