Abstract: A container for holding endodontic instruments that may include a base, a foam pad, a retainer, and a lid. The base may include a well with a bottom and sidewalls extending upwardly from the bottom to an open-ended top. The foam pad may be configured to hold one or more endodontic instruments inserted through the pad, and dimensioned to cover the open-ended top of the well. The retainer may be configured to clamp the foam pad over the open-ended top of the well so that the pad is tautly maintained in a holding position, whereby the foam pad is configured to hold at least a portion of an endodontic instrument within the well. The lid may be coupled to the base, and movable between an open position and a closed position that covers the foam pad.