Patents by Inventor James Joye
James Joye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9050074Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: December 17, 2012Date of Patent: June 9, 2015Assignee: Boston Scientific Scimed, Inc.Inventors: James Joye, Richard S. Williams, Ronald William
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Patent number: 8333758Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: January 5, 2010Date of Patent: December 18, 2012Assignee: Boston Scientific ScimedInventors: James Joye, Richard S. Williams, Ronald Williams
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Patent number: 8177779Abstract: Devices, systems, and methods controllably cool blood vessels and other body lumens. The blood vessel will often be treated for atherosclerotic or other diseases by inflating a balloon so as to engage the surrounding luminal wall. Controlled cooling of the balloon effected by a change in phase of a cryogenic fluid within the balloon typically a change from a liquid phase to a gas phase can be provided with a controlled, gradual inflation of the balloon. A single control system can be used for any of a variety of alternative selectable balloon catheters having significantly differing cooling fluid flow characteristics.Type: GrantFiled: December 2, 2005Date of Patent: May 15, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: James Joye, Richard S. Williams, Glen Reuschling
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Patent number: 8029449Abstract: Methods, apparatus, and kits detect and/or treat vulnerable plaque of a blood vessel. A temperature differential can be sensed along a lumen surface with temperature sensors on a balloon filled with warm gas. Treatment methods include controlled and safe cryogenic cooling of vulnerable plaque to inhibit release of retained fluid within the vulnerable plaque so as to inhibit acute coronary syndrome and to help maintain patency of a body lumen.Type: GrantFiled: August 24, 2010Date of Patent: October 4, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: James Joye, Kristine Tatsutani, Joseph J. Williams
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Publication number: 20110125141Abstract: The present invention provides cryotherapy treatment of dissections in a blood vessel of a patient. The present invention further provides cryotherapy treatment of side branch occlusion in a bifurcated blood vessel. One method for treating potential or existing dissections in a blood vessel comprises cooling the blood vessel to a temperature and for a time sufficient to remodel the blood vessel such that dissections of the blood vessel are reduced. Another method for treating side branch occlusion in a bifurcated blood vessel, the bifurcated blood vessel having a side branch and a main branch, the main branch having plaque disposed thereon, comprises cooling an inner surface of the main branch to a temperature and for a time sufficient to inhibit plaque shift from the main branch into the side branch.Type: ApplicationFiled: December 29, 2010Publication date: May 26, 2011Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: James Joye, Kristine Tatsutani
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Patent number: 7862557Abstract: The present invention provides cryotherapy treatment of dissections in a blood vessel of a patient. The present invention further provides cryotherapy treatment of side branch occlusion in a bifurcated blood vessel. One method for treating potential or existing dissections in a blood vessel comprises cooling the blood vessel to a temperature and for a time sufficient to remodel the blood vessel such that dissections of the blood vessel are reduced. Another method for treating side branch occlusion in a bifurcated blood vessel, the bifurcated blood vessel having a side branch and a main branch, the main branch having plaque disposed thereon, comprises cooling an inner surface of the main branch to a temperature and for a time sufficient to inhibit plaque shift from the main branch into the side branch.Type: GrantFiled: June 14, 2004Date of Patent: January 4, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: James Joye, Kristine Tatsutani
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Publication number: 20100318075Abstract: Methods, apparatus, and kits detect and/or treat vulnerable plaque of a blood vessel. A temperature differential can be sensed along a lumen surface with temperature sensors on a balloon filled with warm gas. Treatment methods include controlled and safe cryogenic cooling of vulnerable plaque to inhibit release of retained fluid within the vulnerable plaque so as to inhibit acute coronary syndrome and to help maintain patency of a body lumen.Type: ApplicationFiled: August 24, 2010Publication date: December 16, 2010Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: JAMES JOYE, KRISTINE TATSUTANI, JOSEPH J. WILLIAMS
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Patent number: 7780608Abstract: Methods, apparatus, and kits detect and/or treat vulnerable plaque of a blood vessel. A temperature differential can be sensed along a lumen surface with temperature sensors on a balloon filled with warm gas. Treatment methods include controlled and safe cryogenic cooling of vulnerable plaque to inhibit release of retained fluid within the vulnerable plaque so as to inhibit acute coronary syndrome and to help maintain patency of a body lumen.Type: GrantFiled: September 16, 2005Date of Patent: August 24, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: James Joye, Kristine Tatsutani, Joseph J. Williams
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Publication number: 20100106148Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: ApplicationFiled: January 5, 2010Publication date: April 29, 2010Inventors: James Joye, Richard S. Williams, Ronald Williams
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Patent number: 7641679Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: October 17, 2005Date of Patent: January 5, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: James Joye, Richard S. Williams, Ronald Williams
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Publication number: 20080065019Abstract: The catheter apparatus may be used to assist in creating a fistula between two adjacent blood vessels. The apparatus includes a catheter for inserting into a first blood vessel which lies adjacent to a second blood vessel, the catheter having a plurality of openings through which a physician may navigate a piercing tool. The physician maneuvers the tip of the catheter to a position within the first blood vessel adjacent to a portion of the first blood vessel wall in which the physician intends to create an opening. The physician may then rotate the piercing tool within the catheter and extend the piercing tool through one opening at a time, without rotating the catheter, until the physician chooses an opening that is properly aimed at the second blood vessel. Such a configuration allows for a wide arc of potential firing space.Type: ApplicationFiled: April 13, 2007Publication date: March 13, 2008Inventors: Richard Heuser, James Joye
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Publication number: 20070203515Abstract: An apparatus is provided for assisting in creating a fistula between a first blood vessel having a first diameter and a second blood vessel. The apparatus includes a catheter with a resizable portion disposed near the distal end of the catheter. The catheter is traversed through the first vessel to a position adjacent to a location intended for a fistula connecting the first vessel to the second vessel. The resizable portion in a nominal configuration has a diameter which is less than the first diameter, allowing traversal through the first vessel. The resizable portion is manipulable to an active configuration having a diameter substantially equal to the first diameter, stabilizing the catheter within the first vessel. The resizable portion may be at least partially radiopaque, and may cover all but a free arc of the outer surface, allowing an unobstructed path for a piercing tool to pass.Type: ApplicationFiled: April 13, 2007Publication date: August 30, 2007Inventors: Richard Heuser, James Joye
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Publication number: 20070203572Abstract: The bifurcated stent apparatus for use by a physician includes a main stent for inserting into a bifurcated blood vessel and a side stent. The main stent has an opening on the side which is the same diameter as the side stent. The main stent may be is configured to receive a first end of the side stent, to create a bifurcated stent. Alternatively, the side stent and the main stent may form a single integrated unit. The side stent includes a one-way valve on the second end. The one-way valve may be opened or closed, depending on whether the physician desires that fluid pass through. While closed, the valve may be configured to allow passage of various cardiovascular instruments, including but not limited to guidewires, catheters, balloons, or any other device used in blood vessel operations, while not allowing the passage of any fluids.Type: ApplicationFiled: April 16, 2007Publication date: August 30, 2007Inventors: Richard Heuser, James Joye
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Publication number: 20070185567Abstract: A stent assembly is provided for preserving and/or dilating a fistula between a first blood vessel and a second blood vessel. The system comprises an expandable stent having a proximal end, a distal end and a stabilizing device adjacent its distal end. The stabilizing portion may have nominal and active configurations. In the nominal configuration, the stabilizing portion may have a diameter less than the diameter of the first or second blood vessels. In the active configuration, the stabilizing portion may have a diameter substantially equal to the diameter of the second blood vessel, thus preserving the diameter of the second blood vessel. Additionally or alternatively, the stent may be divided into three or more sections, with at least one section exhibiting more robust strength. The section with more strength may be positioned within the fistula, thereby preserving the connection between the first blood vessel and the second blood vessel.Type: ApplicationFiled: April 16, 2007Publication date: August 9, 2007Inventors: Richard Heuser, James Joye
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Publication number: 20060212028Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: ApplicationFiled: October 17, 2005Publication date: September 21, 2006Applicant: Cryovascular Systems, Inc.Inventors: James Joye, Richard Williams, Ronald Williams
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Patent number: 7081112Abstract: The invention provides techniques and devices for treating atherosclerotic disease using controlled cryogenic cooling, often in combination with angioplusty. The efficacy of endolusninal cryogenic cooling is enhanced by cooling of target tissues using an insulated cryogenic balloon, the lnsulation ideally comprising a fluid which undergoes a phase change at a predetermined temperature. A combination cryogenic/angioplasty catheter avoids exchange procedures between dilation of a stenotic region within a vessel wall and the application of cryogenic cooling. The combination angioplasty/cryogenic cooling catheter may cool the diseased blood vessel before, during, and/or after dilation. Controlled cooling of the vessel wall may change its mechanical properties, weakening the vessel and allowing it to be expanded at a much lower pressure than with conventional uncooled angioplasty.Type: GrantFiled: August 7, 2002Date of Patent: July 25, 2006Assignee: Cryovascular Systems, Inc.Inventors: James Joye, Kristine Tatsutani, Ronald Williams, Richard S. Williams
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Patent number: 7060062Abstract: Devices, systems, and methods controllably cool blood vessels and other body lumens. The blood vessel will often be treated for atherosclerotic or other diseases by inflating a balloon so as to engage the surrounding luminal wall. Controlled cooling of the balloon effected by a change in phase of a cryogenic fluid within the balloon typically a change from a liquid phase to a gas phase can be provided with a controlled, gradual inflation of the balloon. A single control system can be used for any of a variety of alternative selectable balloon catheters having significantly differing cooling fluid flow characteristics.Type: GrantFiled: June 4, 2003Date of Patent: June 13, 2006Assignee: Cryo Vascular Systems, Inc.Inventors: James Joye, Richard S. Williams, Glen Reuschling
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Publication number: 20060084962Abstract: Devices, systems, and methods controllably cool blood vessels and other body lumens. The blood vessel will often be treated for atherosclerotic or other diseases by inflating a balloon so as to engage the surrounding luminal wall. Controlled cooling of the balloon effected by a change in phase of a cryogenic fluid within the balloon typically a change from a liquid phase to a gas phase can be provided with a controlled, gradual inflation of the balloon. A single control system can be used for any of a variety of alternative selectable balloon catheters having significantly differing cooling fluid flow characteristics.Type: ApplicationFiled: December 2, 2005Publication date: April 20, 2006Applicant: CryoVascular Systems, Inc.Inventors: James Joye, Richard Williams, Glen Reuschling
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Publication number: 20060015092Abstract: Methods, apparatus, and kits detect and/or treat vulnerable plaque of a blood vessel. A temperature differential can be sensed along a lumen surface with temperature sensors on a balloon filled with warm gas. Treatment methods include controlled and safe cryogenic cooling of vulnerable plaque to inhibit release of retained fluid within the vulnerable plaque so as to inhibit acute coronary syndrome and to help maintain patency of a body lumen.Type: ApplicationFiled: September 16, 2005Publication date: January 19, 2006Applicant: CryoVascular Systems, Inc.Inventors: James Joye, Kristine Tatsutani, Joseph Williams
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Patent number: 6972015Abstract: Improved systems, devices, and methods for delivering cryogenic cooling fluid to cryosurgical probes such as cryosurgical endovascular balloon catheters take advantage of the transients during the initiation and termination of cryogenic fluid flow to moderate the treatment temperatures of tissues engaged by the probe. A flow limiting element along a cryogenic fluid path intermittently interrupts the flow of cooling fluid, often cycling both the fluid flow and treatment temperature. This can maintain the tissue treatment temperature within a predetermined range which is above the treatment temperature provided by a steady flow of cryogenic fluid. In another aspect, room temperature single-use cooling fluid cartridges are filled with a sufficient quantity of cryosurgical fluid to effect a desired endovascular cryosurgical treatment.Type: GrantFiled: February 23, 2004Date of Patent: December 6, 2005Assignee: CryoVascular Systems, Inc.Inventors: James Joye, Richard S. Williams, Ronald Williams