Abstract: Co-administration of a channel blocking epithelial sodium channel (ENaC) blocker in conjunction with a mineralocorticoid receptor inhibitor makes it possible to achieve desired lowering of blood pressure with use in the range of 20% to 75% or less of the presently used dosage of the mineralocorticoid receptor inhibitor (MRI), thus avoiding many of the deleterious side effects usually associated with administration of an MRI. As little as 10% of the usual dosage of MRI may, in some cases, be efficacious. The most commonly used ENaC blocker now in use is amiloride. The most commonly used inhibitors of the mineralocorticoid receptor are precursors of canrenone.

Abstract: Co-administration of a channel blocking epithelial sodium channel (ENaC) blocker in conjunction with a mineralocorticoid receptor inhibitor makes it possible to achieve desired lowering of blood pressure with use in the range of 20% to 75% or less of the presently used dosage of the mineralocorticoid receptor inhibitor (MRI), thus avoiding many of the deleterious side effects usually associated with administration of an MRI. As little as 10% of the usual dosage of MRI may, in some cases, be efficacious. The most commonly used ENaC blocker now in use is amiloride. The most commonly used inhibitors of the mineralocorticoid receptor are precursors of canrenone.

Abstract: A golf club grip cleaner (10) is provided, which comprises (a) a cleaning housing (12) provided with a rotatably mounted cleaning tubular chamber (22) sealed at its bottom end with a cap (30), the tubular means provided with a plurality of cleaning brushes (26) mounted on the inside surrface thereof; (b) a power transducer housing (14) provided with a water inlet (32) and a water outlet (34) and a waterwheel (48) mounted on a shaft (52), the waterwheel activated by the flow of water introduced at the water inlet means; (c) a support platform (16) for supporting the cleaning housing above the power transducer housing; and a universal coupling joint (56) for translating the flow of water past the waterwheel to the cleaning tubular chamber. The cleaner permits the efficient and rapid cleaning of golf club grips.

Abstract: Pelagic species of game fish, such as marlin and tuna, are raised from an embryonic, or larval, stage to a juvenile stage by a process and apparatus employing a biologically closed, physically open system. The system is kept biologically closed by first filtering and sterilizing sea water and then growing nutrients for the fish therein. The system is kept physically open by flowing a constant fresh source of sea water through the system to carry nutrient to the fish and to carry waste products out.