Patents by Inventor James K. Chen

James K. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Regulators of the hedgehog pathway, compositions and uses related thereto
    Patent number: 7476661
    Abstract: The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function mutations.
    Type: Grant
    Filed: January 23, 2006
    Date of Patent: January 13, 2009
    Assignee: John Hopkins University School of Medicine
    Inventors: Philip A. Beachy, James K. Chen, Anssi Jussi Nikolai Taipale
  • Regulators of the hedgehog pathway, compositions and uses related thereto
    Publication number: 20080255059
    Abstract: The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function mutations.
    Type: Application
    Filed: March 28, 2008
    Publication date: October 16, 2008
    Applicant: The Johns Hopkins University
    Inventors: Philip A. Beachy, James K. Chen, Anssi Jussi Nikolai Taipale
  • Regulators of the hedgehog pathway, compositions and uses related thereto
    Patent number: 7098196
    Abstract: The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function mutations.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: August 29, 2006
    Assignee: Johns Hopkins University School of Medicine
    Inventors: Philip A. Beachy, James K. Chen, Anssi J. Taipale