Patents by Inventor James K. J. Diss

James K. J. Diss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSIS AND TREATMENT OF CANCER: I
    Publication number: 20100273866
    Abstract: A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or SCN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or SCN9A.
    Type: Application
    Filed: June 7, 2010
    Publication date: October 28, 2010
    Applicant: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: James K. J. Diss, Raoul C. Coombes, Mustafa B. A. Djamgoz, Scott P. Fraser
  • Diagnosis and treatment of cancer:I
    Publication number: 20090074665
    Abstract: A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or SCN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or SCN9A.
    Type: Application
    Filed: February 13, 2008
    Publication date: March 19, 2009
    Applicant: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: James K. J. Diss, Raoul C. Coombes, Mustafa B. A. Djamgoz, Scott P. Fraser
  • Diagnosis and treatment of cancer: I
    Patent number: 7393657
    Abstract: A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or 5CN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or 5CN9A.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: July 1, 2008
    Assignee: Imperial College Innovations Limited
    Inventors: James K. J. Diss, Raoul C. Coombes, Mustafa B. A. Djamgoz, Scott P. Fraser
  • Diagnosis and treatment of cancer:I
    Publication number: 20040146877
    Abstract: A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or 5CN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or 5CN9A.
    Type: Application
    Filed: March 4, 2004
    Publication date: July 29, 2004
    Inventors: James K.J. Diss, Raoul c. Coombes, Mustafa B.A. Djamgoz, Scott P. Fraser