Patents by Inventor James K. Kranz

James K. Kranz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biopharmacuetical Compositions and Related Methods
    Publication number: 20220289859
    Abstract: The invention described herein provides compositions comprising anti-BCMA antigen binding proteins and related methods for treating BCMA mediated diseases or disorders.
    Type: Application
    Filed: July 31, 2020
    Publication date: September 15, 2022
    Inventors: James K. Kranz, Michael Joseph Molloy, Joseph V. Rinella, Jr., Elizabeth Rae Schmidt, Hillary Amber Schuessler, Tejash Shah
  • Assay for evaluating affinity and specificity of ligand-albumin binding
    Patent number: 8476081
    Abstract: A method for identifying a ligand or compound which binds to albumin comprises the steps of contacting a reaction mixture comprising a site-specific probe and albumin in the presence and the absence of the ligand or compound and measuring either dissociation constant KD, inhibitor concentration IC50 or fluorescence displacement; whereby a change in KD, IC50 and/or fluorescence in the presence of the ligand or compound is indicative of the ligand or compound binds to albumin.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: July 2, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: James K. Kranz, Gabrielle C. Todd, Matthew J. Todd
  • ASSAY FOR EVALUATING AFFINITY AND SPECIFICITY OF LIGAND-ALBUMIN BINDING
    Publication number: 20110124120
    Abstract: A method for identifying a ligand or compound which binds to albumin comprises the steps of contacting a reaction mixture comprising a site-specific probe and albumin in the presence and the absence of the ligand or compound and measuring either dissociation constant KD, inhibitor concentration IC50 or fluorescence displacement; whereby a change in KD, IC50 and/or fluorescence in the presence of the ligand or compound is indicative of the ligand or compound binds to albumin.
    Type: Application
    Filed: September 20, 2010
    Publication date: May 26, 2011
    Inventors: James K. Kranz, Gabrielle C. Todd, Matthew J. Todd