Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a subject in vivo. This disclosure also relates to recombinant adeno associated virus (rAAV) capsid proteins comprising one or more amino acid substitutions in the 5-fold region of the rAAV capsid that result in decreased reactivity to neutralizing antibodies, and their use as gene delivery vehicles.

Abstract: A hand washing station includes a basin assembly having a rear configured for mounting to a wall surface and a front opposite the rear. The basin assembly includes a basin having a trough positioned proximate to the rear of the basin assembly and recessed from an adjacent surface of the basin located forward of the trough, with the trough having a front wall extending downward from the adjacent surface and a bottom wall extending rearward from the front wall. The basin assembly also includes a drain within the trough, formed by a slot extending through the front wall. A drain adapter is mounted on the trough below the basin and includes a passage in communication with the drain and extending through the drain adapter to an outlet for connection to a drain pipe, where the drain adapter receives water exiting the drain and outputs the water to the drain pipe.

Abstract: A hand washing station may include a basin assembly having a basin with a drain and a rear wall at a rear of the basin and extending upward from a bottom to a top of the basin, and at least one spout for a water dispenser, a soap dispenser, and/or a hand dryer. The spout(s) may be fixed to the rear wall and extend from the rear wall, and may use a combination of fixed and removable fasteners for such fixing. The basin assembly may also include a flange extending rearwardly at the top of the rear wall for mounting to a top of a pony wall. The station may be configured to install in a variety of different positions and configurations, such as in a pony wall configuration or with a cabinet located below the basin. A drain adapter may also be provided to aid with compact installation.

Abstract: The present disclosure provides AAV capsid proteins comprising a modification in the amino acid sequence and virus vectors comprising the modified AAV capsid protein. The disclosure also provides methods of administering the virus vectors and virus capsids of the disclosure to a cell or to a subject in vivo. This disclosure also relates to recombinant adeno associated virus (rAAV) capsid proteins comprising one or more amino acid substitutions in the 5-fold region of the rAAV capsid that result in decreased reactivity to neutralizing antibodies, and their use as gene delivery vehicles.

Abstract: Disclosed is a water filtration medium capable of removing heavy metals from ground water and surface supplies. This medium comprises a gamma form of manganese dioxide that has been comminuted and divided into fractions according to mesh size, including fractions of 10 to 40 mesh, 40 to 100 mesh, and 100 to 325 mesh. The particles in a given mesh size are treated with a reducing agent such as ferrous sulfate and then washed with water to remove iron precipitates and fines. The washed particles are treated with a solution of sodium hydrosulfite and sodium bisulfite. The treated particles are then neutralized with sodium hydroxide to remove remaining acidity. The neutralized particles are washed again in order to remove spent chemicals and undissolved metals. The particles are then dried prior to use as a filtration medium. Also disclosed is a disposable cartridge for housing the filtration medium, a method of using the medium, and a means for preparing the medium.

Abstract: Asymmetric polyacetylene polymer membranes having both improved selectivity and improved flux are provided by a process which comprises forming a solution containing from about 1 to about 5% by weight of a polyacetylene polymer in any suitable solvent therefor, forming the solution into a thin film and quenching the film in an aqueous bath in the presence of from about 0.002 to about 0.4% by weight of the quench bath of surfactant with an HLB value of 11 to 15. Additionally, the polyacetylene polymer solution contains a swelling agent at about 1% to about 10% by weight of polyacetylene polymer solution.

Abstract: Anisotropic gas separation membranes are treated to alter the microporosity of their thin, dense layer or composite coating--the layer or coating which provides selectivity in separations employing such membranes. The treatment increases the selectivity of a membrane with minimal decrease in its flux. The process comprises applying a polar activator to the membrane followed by exposing the membrane to microwave frequency radiation for a period of time sufficient to compact the thin layer of the membrane. The polar activator may be incorporated in the membrane during fabrication or applied as an after-treatment.

Abstract: Hollow synthetic fibers useful in reverse osmosis, ultrafiltration, gas separation and the like, having high hydraulic permeability to the solvent and capable of operation at pressures from 600 psi and up, are prepared by forming a solution of a fiber-forming polymer in a suitable solvent, adding to the solution a second polymer soluble in the solvent but with limited compatibility with the first polymer when their total concentration increases on coagulation, extruding the resulting solution through an orifice equipped for coaxial extrusion so that coagulating fluid within tube flow results, precipitating with a liquid which is miscible with the solvent for the fiber-forming material, is a non-solvent for the first polymer and a solvent for the second, contacting the extruded solution with the precipitating liquid either coaxially through the extrusion device or by passing the extrudate through the precipitating liquid, and finally washing the resulting hollow fiber free of residual solvents and non-solvents