Abstract: The invention relates to a drug delivery system for contraception including a steroidal estrogenic compound, a steroidal progestogenic compound or a combination thereof for the purposes of contraception in a subject, and provides for an ultra-low dose delivery of a steroidal estrogenic compound which minimizes or eliminates a burst release effect. The invention also relates to a method of contraception using the drug delivery system and method of manufacturing the drug delivery system.

Abstract: One embodiment provides for a method including determining, by at least one processor, sequence-sequence distances for a biological sequence collection. The at least one processor generates a matrix Mij of the sequence-sequence distances, where i and j are positive integers. The at least one processor further generates clusters for the matrix Mij by performing hierarchical clustering. A self-consistent taxonomy is created from the clusters. A visual heat map display of the matrix Mij is selectively controlled using metadata, zoom input and opacity input.

Abstract: One embodiment provides for a method including determining, by at least one processor, sequence-sequence distances for a biological sequence collection. The at least one processor generates a matrix Mij of the sequence-sequence distances, where i and j are positive integers. The at least one processor further generates clusters for the matrix Mij by performing hierarchical clustering. A self-consistent taxonomy is created from the clusters. A visual heat map display of the matrix Mij is selectively controlled using metadata, zoom input and opacity input.

Abstract: Techniques are provided for predicting antibiotic resistance from functional omics data and recommending complementary combinations of antibiotics. According to an embodiment, computer implemented method can comprise identifying, by a system operatively coupled to at least one processor, one or more proteins that have one or more functional domains associated with at least one code selected from a coding system for a set of phenotypes, and modelling, by the system, the one or more proteins as a functional capacity vector. In some implementations, the method can further include selecting the coding system and/or the at least one code based on a phenotype of interest. The method can further comprise employing, by the system, the functional capacity vector to identify one or more antibiotic compounds to which an organism within the set of phenotypes is resistant or susceptible, and/or to predict complementary antibiotic combinations.

Abstract: Systems and methods for receiving customer payment details and generating outgoing payment details on-demand. A network-connected interface can receive customer payment details for payment of an incoming amount. A data store can store a plurality of transaction tracking records including a unique key code and an allocatable amount. A payment gateway can receive authorization data for payment of the incoming amount. An outgoing payment generator can respond to an outgoing payment request comprising an offered key code and an outgoing payment amount if the offered key code matches an existing transaction tracking record in the data store. Outgoing payment details can be generated if the outgoing amount is less than or equal to the allocatable amount. Embodiments can route the transaction such that the customer payment details are passed through to the supplier. Embodiments can make routing and generation decisions based on transaction preferences.

Abstract: Account data (e.g., balance information) for accounts at a plurality of financial institutions (or government agencies) is stored (and updated) in a central database system and accessed using a personal identifier, such as a social security number. Risk data may be generated for accounts based on the account data. The account data and risk data are accessed in response to either an account search request (e.g., from a government entity and relating to a benefits program or a subpoena) or an account verification request (e.g. from a mortgage company and relating to a mortgage application).

Abstract: Account data (e.g., balance information) for accounts at a plurality of financial institutions (or government agencies) is stored (and updated) in a central database system and accessed using a personal identifier, such as a social security number. Risk data may be generated for accounts based on the account data. The account data and risk data are accessed in response to either an account search request (e.g., from a government entity and relating to a benefits program or a subpoena) or an account verification request (e.g. from a mortgage company and relating to a mortgage application).

Abstract: One embodiment provides for a method including determining, by at least one processor, sequence-sequence distances for a biological sequence collection. The at least one processor generates a matrix Mij of the sequence-sequence distances, where i and j are positive integers. The at least one processor further generates clusters for the matrix Mij by performing hierarchical clustering. A self-consistent taxonomy is created from the clusters. A visual heat map display of the matrix Mij is selectively controlled using metadata, zoom input and opacity input.

Abstract: A series of images of a body part of a user is received. The series of images of the body part of the user are captured over a predetermined time period. A feature of the body part is extracted from the series of images, in which a change in appearance of the extracted feature over the predetermined time period is indicative of a potential health condition of the user. The extracted feature is compared to one or more reference images from a knowledge base to determine a difference between the extracted feature and the one or more reference images. The one or more reference images correlate a particular body feature to a particular potential health condition. A potential health condition of the user is detected based upon the comparing. A notification is sent based upon the detected potential health condition.

Abstract: Account data (e.g., balance information) for accounts at a plurality of financial institutions (or government agencies) is stored (and updated) in a central database system and accessed using a personal identifier, such as a social security number. Risk data may be generated for accounts based on the account data. The account data and risk data are accessed in response to either an account search request (e.g., from a government entity and relating to a benefits program or a subpoena) or an account verification request (e.g. from a mortgage company and relating to a mortgage application).

Abstract: Account data (e.g., balance information) for accounts at a plurality of financial institutions (or government agencies) is stored (and updated) in a central database system and accessed using a personal identifier, such as a social security number. Risk data may be generated for accounts based on the account data. The account data and risk data are accessed in response to either an account search request (e.g., from a government entity and relating to a benefits program or a subpoena) or an account verification request (e.g. from a mortgage company and relating to a mortgage application).

Abstract: Systems and methods for detecting aberrant behavior in a testing environment involve receiving real-time audio-visual data from a detection device and executing an application stored in memory that, when executed by a processor, detect aberrant data within the real-time audio-visual data and reacting automatically to the aberrant data.

Abstract: Methods and apparatus for x-ray imaging with focal spot deflection are provided. The apparatus includes an x-ray tube having a cathode configured to emit electrons and an anode having a target with a target surface defining a target angle. The emitted electrons are deflected onto the target surface with the target surface substantially aligned with a z-axis parallel to a gantry rotation axis.

Abstract: Methods and apparatus for x-ray imaging with focal spot deflection are provided. The apparatus includes an x-ray tube having a cathode configured to emit electrons and an anode having a target with a target surface defining a target angle. The emitted electrons are deflected onto the target surface with the target surface substantially aligned with a z-axis parallel to a gantry rotation axis.

Abstract: A method and system are provided for access to distributed data. The system includes a first entity (201-203) storing client data (221-223), the first entity (201-203) requiring access information (220) to access the client data (221-223). A storage device (200), held by the client, provides the access information (220) to access the client data (221-223). A second entity (204) is capable of accessing the stored client data (221-223) from the first entity (201-203) when provided with the access information (220) from the client. A plurality of first entities (201-203) may store client data (221-223) for a single client and the storage device (200) may include a list of the locations and access information (220) for all the first entities (201-203). The storage device (200) may be, for example, a smart card or USB key.

Abstract: Embodiments herein present a system, method, etc. for an efficient super cluster implementation for solving connected problems in a distributed environment. More specifically, the system adapts computing latency to communication latency, wherein the system comprises VPPs wrapped within OCW layers. The VPPs represent a subset of an overall computer task; and, the OCW layers are adapted to enclose the VPPs. Specifically, the number of OCWs that enclose a VPP correspond to the number of computing iterations that may be locally executed by the VPP during an inter-VPP communication cycle. In addition, each VPP comprises collections of OPCs, wherein the OPCs comprise data, methods, and pointers to neighbors. The OPCs are indexed separately based on whether the OPC is part of an OCW layer.

Abstract: Embodiments herein present a virtual memory technique for efficiently solving connected problems in a distributed environment. An exemplary method begins by selectively loading computing task segments into a first node, wherein the number of computing task segments is the maximum number of computing task segments that will fit within the first node. The computing task segments are enclosed within wrappers, wherein the wrappers are streamed into the first node at a maximum rate that a disk can read and write data. Further, the wrappers comprise priority wrappers that must be computed in order to process the computing task segments; and thus, the priority wrappers are loaded into the first node first. In addition, the computing task segments comprise computing task segment block collections, wherein the method creates a list of computing task segment block collection jobs that must be completed in order to process one of the computing task segments.

Abstract: A message pathway selection system dynamically selects an optimum message pathway for transmitting messages. The system dynamically optimizes a message pathway according to various criteria such as, for example, efficiency, economy, data requirements, auditing requirements, security, data size, etc. The system can direct a message to bypass an infrastructure messaging server, using a direct message pathway. The system can also switch from an infrastructure messaging server to a direct method. The system can also utilize an infrastructure messaging pathway either as an alternative or in parallel with the direct message pathway. The system allows an application to use a single communication system for both a direct mode and an infrastructure mode of data transfer. The present system can bypass the infrastructure message pathway, thus reducing message latency, number of messages sent, and improving overall bandwidth.

Abstract: Provided is a method or producing a transgenic animal having modified resistance to a disease. One embodiment of the method is performed by introducing a retrovirus into a cell of the animal or a cell which is capable of producing the animal, wherein the retrovirus comprises a polynucleotide sequence which encodes and is capable of expressing a protein which modifies the disease resistance of the animal, and wherein when the cell is a cell which is capable of producing the animal, producing the animal from the cell.

Abstract: The disclosed massive multi-player on-line gaming environment and method eliminate the coordination and synchronization problems between servers by assigning each game user to a specific client proxy server for game duration and utilizing a space information distribution center to indicate client specific changes in game space. Such configuration eliminates the need to use “grey” areas around partitioning boundaries and servers having to “own” client objects thereby improving massive multi-player on-line gaming scalability.