Patents by Inventor James Kevin Presnail

James Kevin Presnail has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240084319
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
    Type: Application
    Filed: April 27, 2023
    Publication date: March 14, 2024
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E.I. DU PONT DE NEMOURS AND COMPANY
    Inventors: XU HU, JAMES KEVIN PRESNAIL, NINA RICHTMAN, LISA PROCYK
  • Publication number: 20240002842
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: disclosed herein, (but not including the forward and reverse primers.) or active variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiments, the pest is D. virgifera virgifera, D. barberi, D. virgifera zeae, D. speciosa, D.
    Type: Application
    Filed: August 22, 2022
    Publication date: January 4, 2024
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: XU HU, JAMES KEVIN PRESNAIL, NINA RICHTMAN, SCOTT DIEHN, MICHELLE VAN ALLEN, LISA PROCYK
  • Patent number: 11627742
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabarotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 1-236 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is D. virgifera virgifera, D. barberi, D. speciosa, or D. undecimpunctata howardi.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: April 18, 2023
    Assignee: CORTEVA AGRISCIENCE LLC
    Inventors: Karen E Broglie, Kevin Andrew Kriss, Albert L Lu, Mani Muthalagi, James Kevin Presnail
  • Publication number: 20220267792
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
    Type: Application
    Filed: April 29, 2022
    Publication date: August 25, 2022
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: XU HU, BLISS MARIE KERNODLE, MOLLIE MARY MCMAHON, ADANE KASSA, XIPING NIU, JAMES KEVIN PRESNAIL, ALBERT L. LU, NINA RICHTMAN, JONATHAN WILLIAM ROBESON
  • Publication number: 20210321626
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 1-236 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is D. virgifera virgifera, D. barberi, D. speciosa, or D.
    Type: Application
    Filed: April 17, 2021
    Publication date: October 21, 2021
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: KAREN E BROGLIE, KEVIN ANDREW KRISS, ALBERT L LU, MANI MUTHALAGI, JAMES KEVIN PRESNAIL
  • Patent number: 11058119
    Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: July 13, 2021
    Inventors: Denny Joseph Bruck, Frederick C. Burns, II, James Kevin Presnail
  • Publication number: 20210145009
    Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
    Type: Application
    Filed: January 25, 2021
    Publication date: May 20, 2021
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: DENNY JOSEPH BRUCK, FREDERICK C. BURNS, II, JAMES KEVIN PRESNAIL
  • Patent number: 11006633
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 1-236 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is D. virgifera virgifera, D. barberi, D. speciosa, or D. undecimpunctata howardi.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: May 18, 2021
    Inventors: Karen E. Broglie, Kevin Kriss, Albert Lu, Mani Muthalagi, James Kevin Presnail
  • Patent number: 10932471
    Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: March 2, 2021
    Inventors: Denny Joseph Bruck, Frederick C. Burns, II, James Kevin Presnail
  • Patent number: 10876132
    Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with one or more nucleic acid sequence encoding insecticidal protein(s) and one or more silencing element(s). In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The molecular and breeding stacks find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: December 29, 2020
    Assignees: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Scott Henry Diehn, Xu Hu, Albert L. Lu, Lu Liu, James Kevin Presnail, Gary A. Sandahl, Ute Schellenberger, Gusui Wu
  • Publication number: 20200231985
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
    Type: Application
    Filed: April 3, 2020
    Publication date: July 23, 2020
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: XU HU, BLISS MARIE KERNODLE, MOLLIE MARY MCMAHON, ADANE KASSA, XIPING NIU, JAMES KEVIN PRESNAIL, ALBERT L LU, NINA RICHTMAN, JONATHAN WILLIAM ROBESON
  • Publication number: 20200196609
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabarotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 1-236 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is D. virgifera virgifera, D. barberi, D. speciosa, or D. undecimpunctata howardi.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: KAREN E BROGLIE, KEVIN ANDREW KRISS, ALBERT L LU, MANI MUTHALAGI, JAMES KEVIN PRESNAIL
  • Publication number: 20200172918
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
    Type: Application
    Filed: February 13, 2020
    Publication date: June 4, 2020
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: XU HU, JAMES KEVIN PRESNAIL, NINA RICHTMAN, LISA PROCYK
  • Patent number: 10647995
    Abstract: The present invention relates generally to methods of molecular biology and gene silencing to control pests.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: May 12, 2020
    Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Xu Hu, Bliss Marie Kernodle, Molly Mary McMahon, Adane Kassa, Xiping Niu, James Kevin Presnail, Albert L. Lu, Nina Richtman, Jonathan William Robeson
  • Publication number: 20190271004
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity).
    Type: Application
    Filed: May 14, 2019
    Publication date: September 5, 2019
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: RAFAEL HERRMANN, MICHAEL LASSNER, ALBERT L. LU, MARK EDWARD NELSON, JAMES KEVIN PRESNAIL, JANET RICE
  • Publication number: 20190071690
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest, decrease the expression of a target sequence in the pest. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 6-12, 18-40 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
    Type: Application
    Filed: November 16, 2018
    Publication date: March 7, 2019
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Brian McGonigle, James Kevin Presnail, Navdeep Mutti
  • Patent number: 10190134
    Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest, decrease the expression of a target sequence in the pest. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: 6-12, 18-40 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 29, 2019
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Brian McGonigle, James Kevin Presnail, Navdeep Singh Mutti
  • Publication number: 20180338500
    Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
    Type: Application
    Filed: August 1, 2018
    Publication date: November 29, 2018
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: DENNY JOSEPH BRUCK, FREDERICK C. BURNS, II, JAMES KEVIN PRESNAIL
  • Publication number: 20180220658
    Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
    Type: Application
    Filed: April 10, 2018
    Publication date: August 9, 2018
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: DENNY JOSEPH BRUCK, FREDERICK C. BURNS, II, JAMES KEVIN PRESNAIL
  • Patent number: 9993006
    Abstract: Entomopathogenic fungal strains, compositions, and methods of using the strains for reducing overall insect damage.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: June 12, 2018
    Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Denny Joseph Bruck, Frederick C Burns, II, James Kevin Presnail