Abstract: This invention relates to the synthesis of compounds that can be used to treat bacterial infections in combination with other antibacterial agents, and more specifically in combination with a class of antibacterial agents known as carbapenems. The compounds resulting from the novel methods of the present invention are enzyme inhibitors and more particularly are metallo-?-lactamase inhibitors.

Abstract: This invention relates to compounds of formula (I) and methods of treatment using the compounds. The compounds of the invention can be used in combination with antibacterial agents to treat bacterial infections. More specifically, the compounds of formula (I) can be used in combination with a class of antibacterial agents known as carbapenems. The novel compounds of the present invention are enzyme inhibitors and more particularly are metallo-?-lactamase inhibitors.

Abstract: This invention relates to antibacterial drug compounds containing a bicyclic core, typically a bicycle in which one of the rings is an oxazolidinone. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the compounds in treating bacterial infections and in methods of treating bacterial infections.

Abstract: This invention relates to antibacterial drug compounds containing a bicyclic core, typically a bicycle in which one of the rings is an oxazolidinone. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the compounds in treating bacterial infections and in methods of treating bacterial infections.

Abstract: A hand held and hand operated apparatus for analysis of the relationship between numerical values and displayed greyscale of pixels making up an image matrix. The apparatus has a pair of relatively movable members that are located relative to each other to display a greyscale in comparison relationship to window and level scales used to provide rapid analysis of a greyscale distribution of a given image. The members comprise a first cylindrical member concentrically accommodating a cylindrical sleeve. The first member has viewing ports ruled with scales representing values of selected window and level. The sleeve has the greyscale which can be selectively longitudinally and rotatably positioned relative to a viewing port to provide analysis information concerning the greyscale distribution of an image, such as the image on an X-ray film or displayed on a CRT.