Patents by Inventor James Kirkham

James Kirkham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of pyrrole acid derivatives
    Patent number: 12606524
    Abstract: This invention relates to the synthesis of compounds that can be used to treat bacterial infections in combination with other antibacterial agents, and more specifically in combination with a class of antibacterial agents known as carbapenems. The compounds resulting from the novel methods of the present invention are enzyme inhibitors and more particularly are metallo-?-lactamase inhibitors.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: April 21, 2026
    Assignee: INFEX Therapeutics Limited
    Inventors: Andrew Wilkinson, Ian Cooper, David Orr, Jonathan Finlayson, Adam Bunt, James Kirkham, David Lyth, Kevin Blades
  • ANTI-VIRAL COMPOUNDS
    Publication number: 20260078094
    Abstract: This invention relates to compounds that can be used to treat viral infections. The compounds are papain-like protease (PLpro) inhibitors.
    Type: Application
    Filed: September 13, 2023
    Publication date: March 19, 2026
    Inventors: James Kirkham, Ian Cooper, Adam Bunt, Kevin Blades, David Orr, Andrew Wilkinson, David Lyth, Oliver Smith
  • 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors
    Patent number: 12544359
    Abstract: This invention relates to compounds of formula (I) and methods of treatment using the compounds. The compounds of the invention can be used in combination with antibacterial agents to treat bacterial infections. More specifically, the compounds of formula (I) can be used in combination with a class of antibacterial agents known as carbapenems. The novel compounds of the present invention are enzyme inhibitors and more particularly are metallo-?-lactamase inhibitors.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: February 10, 2026
    Assignee: INFEX Therapeutics Limited
    Inventors: Andrew Wilkinson, Ian Cooper, David Orr, Jonathan Finlayson, Adam Bunt, Pia Appelqvist, Hans Wallberg, Fredrik Wångsell, James Kirkham
  • ANTI-VIRAL COMPOUNDS
    Publication number: 20240383852
    Abstract: This invention relates to compounds that can be used to treat viral infections. The compounds are papain-like protease (PLpro) inhibitors.
    Type: Application
    Filed: March 11, 2022
    Publication date: November 21, 2024
    Inventors: James Kirkham, Ian Cooper, Adam Bunt, Kevin Blades, David Orr, Andrew Wilkinson, Paul Schofield
  • SYNTHESIS OF PYRROLE ACID DERIVATIVES
    Publication number: 20230286915
    Abstract: This invention relates to the synthesis of compounds that can be used to treat bacterial infections in combination with other antibacterial agents, and more specifically in combination with a class of antibacterial agents known as carbapenems. The compounds resulting from the novel methods of the present invention are enzyme inhibitors and more particularly are metallo-?-lactamase inhibitors.
    Type: Application
    Filed: October 6, 2021
    Publication date: September 14, 2023
    Inventors: Andrew Wilkinson, lan Cooper, David Orr, Jonathan Finlayson, Adam Bunt, James Kirkham, David Lyth, Kevin Blades
  • 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS
    Publication number: 20230018460
    Abstract: This invention relates to compounds of formula (I) and methods of treatment using the compounds. The compounds of the invention can be used in combination with antibacterial agents to treat bacterial infections. More specifically, the compounds of formula (I) can be used in combination with a class of antibacterial agents known as carbapenems. The novel compounds of the present invention are enzyme inhibitors and more particularly are metallo-?-lactamase inhibitors.
    Type: Application
    Filed: November 19, 2020
    Publication date: January 19, 2023
    Inventors: Andrew Wilkinson, Ian Cooper, David Orr, Jonathan Finlayson, Adam Bunt, Pia Appelqvist, Hans Wallberg, Fredrik Wångsell, James Kirkham
  • Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds
    Patent number: 10487093
    Abstract: This invention relates to antibacterial drug compounds containing a bicyclic core, typically a bicycle in which one of the rings is an oxazolidinone. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the compounds in treating bacterial infections and in methods of treating bacterial infections.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: November 26, 2019
    Assignee: Redx Pharma PLC
    Inventors: Ian Cooper, Amanda Lyons, David Orr, James Kirkham, Kevin Blades
  • HETEROCYCLIC COMPOUNDS, IN PARTICULAR 2-OXO-4,4,5,5,6,6,7,7-OCTAHYDROBENZOXAZOLE DERIVATIVES, AND THEIR USE AS ANTIBACTERIAL COMPOUNDS
    Publication number: 20190055266
    Abstract: This invention relates to antibacterial drug compounds containing a bicyclic core, typically a bicycle in which one of the rings is an oxazolidinone. It also relates to pharmaceutical formulations of antibacterial drug compounds. It also relates to uses of the compounds in treating bacterial infections and in methods of treating bacterial infections.
    Type: Application
    Filed: February 8, 2017
    Publication date: February 21, 2019
    Inventors: Ian Cooper, Amanda Lyons, David Orr, James Kirkham, Kevin Blades