Abstract: New methods and machine implemented systems measure patient health symptoms and clinical endpoints, communicate prescribed exercise programs to patients, coach or encourage patients to exert themselves within a predetermined protocol or beyond accustomed levels (in treatment of Parkinson's disease), or below accustomed levels (in treatment of cardiac rehabilitation), track patient compliance to exercise instructions, record and commutate data for physician review and for system optimization wherein databases of exercise programs may be modified to comport with measured patient success. Measurements of patient exercises and health changes are also used to provide refined diagnosis and status of disease. Individual exercise programs may be modified in response to physician input and/or patient progress. The continues loop feedback between a patient and the system optimizes the use of exercise as a treatment for disease.

Abstract: A multi-stage dilution device, comprising a first stage dilution apparatus (A), and a second stage dilution apparatus (B), each of the stage dilution device comprising: (i) a housing (1) having a diluent inlet (7); (ii) a sample inlet (2) having a sample introducer within the housing (1) adapted to introduce the sample at an introducer point (4) within the housing (1); and, (iii) a mixing conduit (5) mounted at least partially within the housing (1), the mixing conduit (5) having an inlet section comprising a mouth (10), and a fluid outlet (8), and a throat section (9) capable of producing a pressure drop within the mixing conduit (5), the pressure drop being sufficient to draw sample through the sample inlet (2); the introducer point (4) of the sample inlet (2) being proximate the mixing conduit inlet; and wherein the fluid output (8) of the first stage dilution apparatus (A) is in communication with the sample inlet (2) of the second stage dilution apparatus (B).

Abstract: A powered hand held device having an improved power supply with both a low power source in parallel with a high power source from ultracapacitors. The ultracapacitor power is used by the device motor during certain peak power demands which require high power to the device motor. An improved hand held tube cutter tool is provided both with and without the improved power arrangement, and includes a rotating cutter head assembly with an adjustable roller assembly providing a superior tube cut.