Abstract: This invention relates to novel isothiazolopyridinones of the formula: ##SPC1##Wherein Y is hydrogen, (C.sub.1 --C.sub.12)alkyl, aralkyl of up to 11 carbon atoms, (C.sub.1 -C.sub.4)alkylcarbonyl, (C.sub.6 -C.sub.10)arylcarbonyl, aralkyl-carbonyl of up to 11 carbon atoms, (C.sub.2 -C.sub.3)hydroxyalkyl, a group of the formula: ##EQU1## wherein R.sup.4 is hydrogen, (C.sub.1 -C.sub.4)alkyl or phenyl and R.sup.5 and R.sup.6 are individually (C.sub.1 -C.sub.4)alkyl or taken together with the nitrogen atom to which they are attached, form a 5 or 6 membered azacyclic ring, which can include as additional hetero atoms, O, S or N or any combination of these wherein the total number of hetero atoms does not exceed 3; or a carbamoyl group of the formula: ##EQU2## wherein R.sup.7 is (C.sub.1 -C.sub.18)alkyl, (C.sub.6 -C.sub.10)aryl or aralkyl of up to 11 carbon atoms; R.sup.1 and R.sup.3 are individually hydrogen, (C.sub.1 -C.sub.4)alkyl, phenyl or benzyl; and R.sup.2 is hydrogen or (C.sub.1 -C.sub.